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Protein Overview: RRN6

General Information:
Name(s) found: RRN6 / YBL014C [SGD]
Description(s) found:
Found 22 descriptions.
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  • Component of the core factor (CF) rDNA transcription factor complex; CF is required for transcription of 35S rRNA genes by RNA polymerase I and is composed of Rrn6p, Rrn7p, and Rrn11p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 894 amino acids

    Gene Ontology:
    Cellular Component: RNA polymerase I transcription factor complex [TASLink to PubMed article]
    Biological Process: transcription from RNA polymerase I promoter [TASLink to PubMed article]
    Molecular Function: RNA polymerase I transcription factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEGQIPSSD VLGSQLGVGV QGASLYCPQE NYTTKKQENP QWLRPVDDTL AEDALDLHIV  60
   61 VKSLLCDTAI RYISDDKVLQ ESDADDDLIT SDIDEDTDNQ GDTSIVVNPV IPVVPKDVHF 120
  121 FKKVDVGNDS MFGVNCDTPV SFQDYIPSDL LRNLDDTLQE STNSSRPMQD AFFWDPTVAN 180
  181 RLDSQYIQTA SDLRNYRDGT EIIAYASGKT GSVLNIAVLT RQNTLHLNRH NNVTSIELHS 240
  241 PIKSIKIPGA SESIGRRSNL VGIITENSFQ IFRIESVHSR SCDVMVSSSE PLYFVEIDDL 300
  301 QVVDFAFNPW DLQQFAIIDI KGNWSIGRIP KNFNNNNKRK LQLIDNLHGT IFDPEELSSW 360
  361 KRIEWFSHFQ KILVFDRSKM IEIDFMNNWQ TEVVQAKAWS NIRDYKRIDD KNGILLTSRE 420
  421 IIIVGASESN DPVRRISWKH DLDPDDTTLR ITVQKVKKPD HILLVAFVYS MRHKRIYMHV 480
  481 FSHRKANLFQ SLGCSTVLEI PGGTPTGIET ILTLDHIDDE SRREEDADEN FELVVDFLVK 540
  541 LRNSSEVYYY ALSNTQNSEP NKQETPIIVD HPEWASLFNN ADEREKESIG ALVSQIKLKE 600
  601 RERISRVQNL IEHENSHDED KYLQDLGYRL SIATNELLES WQKTKDESIL SGSLSHSKLK 660
  661 NLLENSDSFA SIPEFSSLLD QFFQYYQDQD VTFIGFEKLL HLFLHEDVPG LDIFYNKLLQ 720
  721 CWVLVSPQAE LLTKEIVKDI IWSLARLEKP SLFEPIQNEI SRSLSGPYQD IISSWDMDDI 780
  781 NEEDESNEFN FDSQFSAPFN GRPPFNLNSQ SQIPTIKSSQ SSGLARRKRI LKTQSQKATP 840
  841 LSQSTQNLSV LPDSMTPAFT LMQPPSSQIS FVNDSQPRNS QKAKKKKKRI RGFG

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) RRN6 SLM5 SPS22
    View Details (MIPS) Mewes HW, et al. (2004) RRN11 RRN6 RRN7 SPT15
    View Details Krogan NJ, et al. (2006) RRN11 RRN6 RRN7
    View Details Qiu et al. (2008) RRN10 RRN11 RRN3 RRN5 RRN6 RRN7 RRN9 SPT15 TFB5 UAF30

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RRN6 and NOP56 Huh WK, et al. (2003)
    View Data RRN6 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..894] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle