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Protein Overview: SPS22

General Information:
Name(s) found: SPS22 / YCL048W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Protein of unknown function, redundant with Sps2p for the organization of the beta-glucan layer of the spore wall [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 463 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [ISSLink to PubMed article]
    Biological Process: cellular cell wall organization [ISSLink to PubMed article]
    ascospore wall assembly [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRITRKSCL FAIIFASLFV THALGAAIDP PRRPHNVKPF HNGNLELQRR ANEPFFEIDV  60
   61 KSLNTNSPIS ELCKKDLHVI ESSHDLFHLQ NQCEFILGSL KVTNYDSNIL DLNSLRAIGG 120
  121 DLIIQDSPEL IRIQAGNLNK IEGLFQLQGL TSLVSVEIPT LKFCQSLEWK VVPILNYVSM 180
  181 DSQNIEIIKD IVISDTSLAN IENFNKVQEI DTFNINNNRF LETIHSNVKT IRGQFSVHAN 240
  241 AKELELEMPH LREVENITIR DTSLVYLPQL TKVKSSLEFI ENYFYELNLN NLQKIGGTLG 300
  301 IINNVNLIKV NLENLTDIQG GLMIADNESL EDITFLPNLK QIGGAIFFEG SFKDIMFDSL 360
  361 KLVKGSAFIK SSSNVLDCNK WTNPSNGRSI IRGGKFTCIS GKKENTLNVK QDGTIIEKGY 420
  421 KDLTQEGEDS KKRVISKYAN SANPSMQLDP LLFGTCLVAM LLF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) RRN6 SLM5 SPS22

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run BOI1 Sample boi1 with gst from october 2005 McCusker D, et al (2007)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..166] PSI-BLAST 23.522879 Type 1 insulin-like growth factor receptor extracellular domain; Type 1 insulin-like growth factor receptor Cys-rich domain
    2 View Details [167..411] PSI-BLAST 8.0 Leucine rich effector protein YopM
    3 View Details [412..463] deduced N/A Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor activity
    		•  1.64987101746707 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.34503183418293 bayes_pls_golite062009
  • binding
    		•  1.08525898490902 bayes_pls_golite062009
  • protein binding
    		•  0.669091045213589 bayes_pls_golite062009
  • signal transducer activity
    		•  0.499118819144462 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.499118819144462 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle