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Protein Overview: RRN5

General Information:
Name(s) found: RRN5 / YLR141W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Protein involved in transcription of rDNA by RNA polymerase I; transcription factor, member of UAF (upstream activation factor) family along with Rrn9p and Rrn10p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 363 amino acids

    Gene Ontology:
    Cellular Component: RNA polymerase I upstream activating factor complex [TASLink to PubMed article]
    Biological Process: transcription from RNA polymerase I promoter [TASLink to PubMed article]
    Molecular Function: RNA polymerase I transcription factor activity [TASLink to PubMed article]
    rDNA binding [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEHQQLRKYV ELYNKEVEEF YNGAASGRPA EFHPSKVHVK SIHEKAGTAN AGVEISSVGV  60
   61 DWDSEEKNTF FWCLSRYSIH RVDEWRSLLP RKSAMEILGY YRLLRRASAS ARSRKAGDDG 120
  121 APIAYEMSAE WVALETKLSE TVMAITEGAA EVADEEGHCE GLIDYESWKR RWVAIYSHSR 180
  181 IAEIRPLPRH ALPLSRSATQ TLERCVSRYT RTLLWCTALA GMASRSVSAR AAESRGHKSL 240
  241 PTVVTRRQVE RALCTEARSR DLHVLPRRIV LTLRKWELDY PREGKLFRTK EMAHLFLQSQ 300
  301 LSRRDAPPVH QDENQENQEN QENQEQDNTA SEGESEAERD EIDEADLFRS ALHENQLLKW 360
  361 LSK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) RRN10 RRN5 RRN9
    View Details Qiu et al. (2008) RRN10 RRN11 RRN3 RRN5 RRN6 RRN7 RRN9 SPT15 UAF30

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RRN5 and NOP56 Huh WK, et al. (2003)
    View Data RRN5 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..363] deduced N/A No confident structure predictions are available.
    2 View Details [156..363] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle