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Protein Overview: CCE1

General Information:
Name(s) found: CCE1 / YKL011C [SGD]
Description(s) found:
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  • pir||S19635 cruciform-cutting endonuclease 1 - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|6322841|ref|NP_012914.1| Mitochondrial cruciform cutting endonuclease, cleaves Holliday junctions formed during recombination of mitochondrial DNA; Cce1p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|485995|emb|CAA81846.1| CCE1 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|416770|sp|Q03702.1|CCE1_YEAST RecName: Full=Cruciform cutting endonuclease 1, mitochondrial; Flags: Precursor [NCBI NR]
  • gi|171175|gb|AAB02883.1| cruciform cutting endonuclease 1 [NCBI NR]
  • gi|1680475|gb|AAB24906.1|S53418_2 CCE1 gene product [Saccharomyces cerevisiae] [NCBI NR]
  • Cruciform cutting endonuclease 1, mitochondrial OS=Saccharomyces cerevisiae GN=CCE1 PE=1 SV=1 [Swiss-Prot]
  • CCE1 Cruciform-cutting endonuclease, mitochondrial [mips]
  • Mitochondrial cruciform cutting endonuclease, cleaves Holliday junctions formed during recombination of mitochondrial DNA [SGD]
  • CCE1, Chr XI from 419793-420854, reverse complement [yeast_orfs2]
  • Chr XI from 419793-420854, reverse complement [yeastorf3.fasta]
  • Chr XI from 420854-419793, reverse complement [yeastorf5.fasta]
  • (Q03702) Cruciform cutting endonuclease 1, mitochondrial precursor (EC 3.1.-.-) [4932.FASTACCERV.txt]
  • CCE1 SGDID:S0001494, Chr XI from 420859-419798, reverse complement, Verified ORF [yeastflysequest.fasta]
  • Cce1p [Saccharomyces cerevisiae]gi|485995|emb|CAA81846.1| CCE1 [Saccharomyces cerevisiae]gi|416770|sp|Q03702|CCE1_YEAST Cruciform cutting endonuclease 1, mitochondrial precursorgi|82963|pir||S19635 cruciform-cutting endonuclease 1 - yeast (Saccharomyce [nrdb_11152004_Chlamydomonas]
  • CCE1 SGDID:S000001494, Chr XI from 420859-419798, reverse complement, Verified ORF, "Mitochondrial cruciform cutting endonuclease, cleaves Holliday junctions formed during recombination of mitochondrial DNA" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • cruciform cutting endonuclease 1 [nr-271106-contam.fasta]
  • CCE1 gene product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Mitochondrial cruciform cutting endonuclease, cleaves Holliday junctions formed during recombination of mitochondrial DNA; Cce1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • CCE1 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Cruciform cutting endonuclease 1, mitochondrial precursor [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Cruciform cutting endonuclease 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CCE1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • CCE1 SGDID:S000001494, Chr XI from 421216-420155, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial cruciform cutting endonuclease, cleaves Holliday junctions formed during recombination of mitochondrial DNA" [yeast-030211-contam.fasta]
  • CCE1 SGDID:S000001494, Chr XI from 421216-420155, Genome Release 64-2-1, reverse complement, Verified ORF, "Mitochondrial cruciform cutting endonuclease; cleaves Holliday junctions formed during recombination of mitochondrial DNA; CCE1 has a paralog, MRS1, that arose from the whole genome duplication" [20141208_orf_trans.fasta]
  • TR4432|c0_g1_i1|g.3131 ORF TR4432|c0_g1_i1|g.3131 TR4432|c0_g1_i1|m.3131 type:complete len:354 (+) TR4432|c0_g1_i1:4776-5837(+) [Y12_S_cerevisiae-Sep2015-contam.fasta]
  • YKL011C SGDID:S000001494, Chr XI from 421216-420155, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial cruciform cutting endonuclease, cleaves Holliday junctions formed during recombination of mitochondrial DNA" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
  • asmbl_6424|g.4753 ORF asmbl_6424|g.4753 asmbl_6424|m.4753 type:complete len:354 (+) asmbl_6424:4808-5869(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta]
  • ID=asmbl_6445|g.4024 ORF ID=asmbl_6445|g.4024 ID=asmbl_6445|m.4024 type:complete len:354 (+) ID=asmbl_6445:4808-5869(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 353 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial inner membrane [IDALink to PubMed article]
    Biological Process: DNA recombination [TASLink to PubMed article]
    Molecular Function: endodeoxyribonuclease activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTAQKAKIL QLIDSCCQNA KSTQLKSLSF VIGAVNGTTK EAKRTYIQEQ CEFLEKLRQQ  60
   61 KIREGRINIL SMDAGVSNFA FSKMQLLNND PLPKVLDWQK INLEEKFFQN LKKLSLNPAE 120
  121 TSELVFNLTE YLFESMPIPD MFTIERQRTR TMSSRHILDP ILKVNILEQI LFSNLENKMK 180
  181 YTNKIPNTSK LRYMVCSSDP HRMTSYWCIP REETPTSSKK LKSNKHSKDS RIKLVKKILS 240
  241 TSILEGNSTS STKLVEFIGV WNNRIRNALT KKKSFKLCDI LEIQDNSGVR KDDDLADSFL 300
  301 HCLSWMEWLK NYESITELLN SKTLVKTQFG QVFEFCENKV QKLKFLQNTY NND

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) CCE1 CTF4 RAD14 RAD16 RNR3
    View Details Qiu et al. (2008) CCE1 NUC1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CCE1 NRG1 1 Unpublished Fields Lab Data
    View Screen CCE1 RPB8 1 Unpublished Fields Lab Data
    View Screen CCE1 MRP20 1 Unpublished Fields Lab Data
    View Screen CCE1 RRS1 1 Unpublished Fields Lab Data
    View Screen CCE1 BNA7 1 Unpublished Fields Lab Data
    View Screen CCE1 YOR343C 1 Unpublished Fields Lab Data
    View Screen CCE1 TIF35 1 Unpublished Fields Lab Data
    View Screen CCE1 SET6 1 Unpublished Fields Lab Data
    View Screen CCE1 MZM1 1 Unpublished Fields Lab Data
    View Screen CCE1 MAK3 1 Unpublished Fields Lab Data
    View Screen CCE1 IRC22 1 Unpublished Fields Lab Data
    View Screen CCE1 TDA6 1 Unpublished Fields Lab Data
    View Screen CCE1 SDA1 1 Unpublished Fields Lab Data
    View Screen CCE1 KRE6 1 Unpublished Fields Lab Data
    View Screen CCE1 URM1 1 Unpublished Fields Lab Data
    View Screen CCE1 RPB4 1 Unpublished Fields Lab Data
    View Screen CCE1 YKR033C 1 Unpublished Fields Lab Data
    View Screen CDC48 CCE1 1 Unpublished Fields Lab Data
    View Screen CCE1 YSR3 1 Unpublished Fields Lab Data
    View Screen MIG1 CCE1 1 Unpublished Fields Lab Data
    View Screen CCE1 HBS1 1 Unpublished Fields Lab Data
    View Screen CCE1 TRM7 1 Unpublished Fields Lab Data
    View Screen CCE1 CIN4 1 Unpublished Fields Lab Data
    View Screen CCE1 PHO2 1 Unpublished Fields Lab Data
    View Screen CCE1 YMR265C 1 Unpublished Fields Lab Data
    View Screen CCE1 CDC48 1 Unpublished Fields Lab Data
    View Screen CCE1 SSN8 1 Unpublished Fields Lab Data
    View Screen CCE1 YDR026C 1 Unpublished Fields Lab Data
    View Screen CCE1 HEM15 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CCE1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..353] PSI-BLAST 123.38764 Mitochondrial resolvase ydc2 N-terminal domain; Mitochondrial resolvase ydc2 catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nuclease activity
    		•  2.42408996498686 bayes_pls_golite062009
  • exonuclease activity
    		•  2.2254764376369 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.75713164321634 bayes_pls_golite062009
  • hydrolase activity
    		•  1.66727833471421 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.41033617404868 bayes_pls_golite062009
  • catalytic activity
    		•  1.25233849524628 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.19309748194103 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  1.1219517187744 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.72566997912926 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.717600245625866 bayes_pls_golite062009
  • endonuclease activity
    		•  0.635517699603511 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.568273228950698 bayes_pls_golite062009
  • binding
    		•  0.332806037334937 bayes_pls_golite062009
  • exodeoxyribonuclease activity
    		•  0.278838342302102 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
    		•  0.261428436029202 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.14466215642144 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.129994528216387 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.0662718964590603 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle