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Protein Overview: CCE1

General Information:
Name(s) found: CCE1 / YKL011C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Mitochondrial cruciform cutting endonuclease, cleaves Holliday junctions formed during recombination of mitochondrial DNA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 353 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial inner membrane [IDALink to PubMed article]
    Biological Process: DNA recombination [TASLink to PubMed article]
    Molecular Function: endodeoxyribonuclease activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTAQKAKIL QLIDSCCQNA KSTQLKSLSF VIGAVNGTTK EAKRTYIQEQ CEFLEKLRQQ  60
   61 KIREGRINIL SMDAGVSNFA FSKMQLLNND PLPKVLDWQK INLEEKFFQN LKKLSLNPAE 120
  121 TSELVFNLTE YLFESMPIPD MFTIERQRTR TMSSRHILDP ILKVNILEQI LFSNLENKMK 180
  181 YTNKIPNTSK LRYMVCSSDP HRMTSYWCIP REETPTSSKK LKSNKHSKDS RIKLVKKILS 240
  241 TSILEGNSTS STKLVEFIGV WNNRIRNALT KKKSFKLCDI LEIQDNSGVR KDDDLADSFL 300
  301 HCLSWMEWLK NYESITELLN SKTLVKTQFG QVFEFCENKV QKLKFLQNTY NND

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) CCE1 CTF4 RAD14 RAD16 RNR3
    View Details Qiu et al. (2008) CCE1 NUC1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CCE1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..353] PSI-BLAST 123.38764 Mitochondrial resolvase ydc2 N-terminal domain; Mitochondrial resolvase ydc2 catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nuclease activity
    		•  2.42408996498686 bayes_pls_golite062009
  • exonuclease activity
    		•  2.2254764376369 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.75713164321634 bayes_pls_golite062009
  • hydrolase activity
    		•  1.66727833471421 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.41033617404868 bayes_pls_golite062009
  • catalytic activity
    		•  1.25233849524628 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.19309748194103 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  1.1219517187744 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.72566997912926 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.717600245625866 bayes_pls_golite062009
  • endonuclease activity
    		•  0.635517699603511 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.568273228950698 bayes_pls_golite062009
  • binding
    		•  0.332806037334937 bayes_pls_golite062009
  • exodeoxyribonuclease activity
    		•  0.278838342302102 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
    		•  0.261428436029202 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.14466215642144 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.129994528216387 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.0662718964590603 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle