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View Structure Prediction Details

Protein: CCE1
Organism: Saccharomyces cerevisiae
Length: 353 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CCE1.

Description E-value Query
Range
Subject
Range
gi|190409811 - gi|190409811|gb|EDV13076.1| cruciform cutting endonuclease [Saccharomyces cerevisiae RM11-1a]
CCE1 - Mitochondrial cruciform cutting endonuclease, cleaves Holliday junctions formed during recombination...
gi|151941534 - gi|151941534|gb|EDN59897.1| cruciform cutting endonuclease [Saccharomyces cerevisiae YJM789]
CCE1_YEAST - Cruciform cutting endonuclease 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2...
0.0 [1..353] [1..353]
MRS1_SACPA - Mitochondrial RNA-splicing protein MRS1 OS=Saccharomyces paradoxus GN=MRS1 PE=4 SV=1
MRS1_SACDO - Mitochondrial RNA-splicing protein MRS1 OS=Saccharomyces douglasii GN=MRS1 PE=4 SV=1
4.0E-80 [9..319] [10..321]
cce1 - mitochondrial cruciform cutting endonuclease Cce1
CCE1_SCHPO - Cruciform cutting endonuclease 1, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 2484...
1.0E-65 [69..314] [42..250]

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Predicted Domain #1
Region A:
Residues: [1-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTAQKAKIL QLIDSCCQNA KSTQLKSLSF VIGAVNGTTK EAKRTYIQEQ CEFLEKLRQQ  60
   61 KIREGRINIL SMDAGVSNFA FSKMQLLNND PLPKVLDWQK INLEEKFFQN LKKLSLNPAE 120
  121 TSELVFNLTE YLFESMPIPD MFTIERQRTR TMSSRHILDP ILKVNILEQI LFSNLENKMK 180
  181 YTNKIPNTSK LRYMVCSSDP HRMTSYWCIP REETPTSSKK LKSNKHSKDS RIKLVKKILS 240
  241 TSILEGNSTS STKLVEFIGV WNNRIRNALT KKKSFKLCDI LEIQDNSGVR KDDDLADSFL 300
  301 HCLSWMEWLK NYESITELLN SKTLVKTQFG QVFEFCENKV QKLKFLQNTY NND

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 123.38764
Match: 1kcfA_
Description: Mitochondrial resolvase ydc2 N-terminal domain; Mitochondrial resolvase ydc2 catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nuclease activity 2.42408996498686 bayes_pls_golite062009
exonuclease activity 2.2254764376369 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.75713164321634 bayes_pls_golite062009
hydrolase activity 1.66727833471421 bayes_pls_golite062009
ribonuclease activity 1.41033617404868 bayes_pls_golite062009
catalytic activity 1.25233849524628 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.19309748194103 bayes_pls_golite062009
deoxyribonuclease activity 1.1219517187744 bayes_pls_golite062009
3'-5' exonuclease activity 0.72566997912926 bayes_pls_golite062009
DNA polymerase activity 0.717600245625866 bayes_pls_golite062009
endonuclease activity 0.635517699603511 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.568273228950698 bayes_pls_golite062009
binding 0.332806037334937 bayes_pls_golite062009
exodeoxyribonuclease activity 0.278838342302102 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.261428436029202 bayes_pls_golite062009
exoribonuclease activity 0.14466215642144 bayes_pls_golite062009
nucleic acid binding 0.129994528216387 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 0.0662718964590603 bayes_pls_golite062009

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