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Protein Overview: VID28

General Information:
Name(s) found: VID28 / YIL017C [SGD]
Description(s) found:
Found 23 descriptions.
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  • Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); localized to the nucleus and the cytoplasm [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 921 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: ascospore formation [IMPLink to PubMed article]
    proteasomal ubiquitin-dependent protein catabolic process [IMPLink to PubMed articleLink to PubMed article]
    response to drug [IMPLink to PubMed article]
    negative regulation of gluconeogenesis [IMPLink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    vacuolar protein catabolic process [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVAYSLENL KKISNSLVGD QLAKVDYFLA PKCQIFQCLL SIEQSDGVEL KNAKLDLLYT  60
   61 LLHLEPQQRD IVGTYYFDIV SAIYKSMSLA SSFTKNNSST NYKYIKLLNL CAGVYPNCGF 120
  121 PDLQYLQNGF IQLVNHKFLR SKCKIDEVVT IIELLKLFLL VDEKNCSDFN KSKFMEEERE 180
  181 VTETSHYQDF KMAESLEHII VKISSKYLDQ ISLKYIVRLK VSRPASPSSV KNDPFDNKGV 240
  241 DCTRAIPKKI NISNMYDSSL LSLALLLYLR YHYMIPGDRK LRNDATFKMF VLGLLKSNDV 300
  301 NIRCVALKFL LQPYFTEDKK WEDTRTLEKI LPYLVKSFNY DPLPWWFDPF DMLDSLIVLY 360
  361 NEITPMNNPV LTTLAHTNVI FCILSRFAQC LSLPQHNEAT LKTTTKFIKI CASFAASDEK 420
  421 YRLLLLNDTL LLNHLEYGLE SHITLIQDFI SLKDEIKETT TESHSMCLPP IYDHDFVAAW 480
  481 LLLLKSFSRS VSALRTTLKR NKIAQLLLQI LSKTYTLTKE CYFAGQDFMK PEIMIMGITL 540
  541 GSICNFVVEF SNLQSFMLRN GIIDIIEKML TDPLFNSKKA WDDNEDERRI ALQGIPVHEV 600
  601 KANSLWVLRH LMYNCQNEEK FQLLAKIPMN LILDFINDPC WAVQAQCFQL LRNLTCNSRK 660
  661 IVNILLEKFK DVEYKIDPQT GNKISIGSTY LFEFLAKKMR LLNPLDTQQK KAMEGILYII 720
  721 VNLAAVNENK KQLVIEQDEI LNIMSEILVE TTTDSSSNGN DSNLKLACLW VLNNLLWNSS 780
  781 VSHYTQYAIE NGLEPGHSPS DSENPQSTVT IGYNESVAGG YSRGKYYDEP DGDDSSSNAN 840
  841 DDEDDDNDEG DDEGDEFVRT PAAKGSTSNV QVTRATVERC RKLVEVGLYD LVRKNITDES 900
  901 LSVREKARTL LYHMDLLLKV K

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) FYV10 GID7 GID8 RMD5 VID24 VID28 VID30 YDL176W
    View Details Krogan NJ, et al. (2006) FYV10 GID7 GID8 RMD5 VID24 VID28 VID30 YDL176W
    View Details Ho Y, et al. (2002) CCT2 CCT3 FYV10 GID7 GID8 HXT7 MOH1 RMD5 TFP1 VID28 VID30

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data VID28 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..340] deduced N/A No confident structure predictions are available.
    2 View Details [341..503] PSI-BLAST 7.0 Importin beta
    3 View Details [504..615] PSI-BLAST 62.0 Importin alpha
    4 View Details [616..668] PSI-BLAST 62.0 Importin alpha
    5 View Details [669..825] PSI-BLAST 62.0 Importin alpha
    6 View Details [826..921] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle