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Protein Overview: GID7

General Information:
Name(s) found: GID7 / YCL039W [SGD]
Description(s) found:
Found 21 descriptions.
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  • Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains six WD40 repeats; computational analysis suggests that Gid7p and Moh1p have similar functions [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 745 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: negative regulation of gluconeogenesis [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHTNKIAYV LNNDTEETAS PSSVGCFDKK QLTKLLIHTL KELGYDSAAN QLLLESGGYQ  60
   61 NESNHIQTFF KLIKTGQFHL INWQIVCSLP LAHSSPLRSE WLQRLLIPTP TPATTSLFDH 120
  121 MLLQLQYLQQ LMSSVNSSTC SDAEIATLRN YVEIMILVNR QIFLEFFHPV TNSASHKGPH 180
  181 TALPVLYLRK ILKNFIEIWD SLLVSNDQFL NEENIFNPET TLRELSTYLT NPKLTAQLNL 240
  241 ERDHLIDAIS KYIDPNELVP KGRLLHLLKQ AIKYQQSQDI FNIIDPDDDA SFSSPPHRIN 300
  301 LLQDNFSHDL TVTFQEWKTI QDTTDEIWFL TFSPNGKYLA SATSESSRGY FITVYDVEQD 360
  361 FKIYKTCVSL SQSVLYLMFS PDSRYLVACP FSEDVTIYDM NATSLPDASA TDSFLLYPST 420
  421 RLSPMDSFKL DTTTYPDDTE SSASSSSRPA NANSNQSRVW CCDAFHTAER AGWMVVGSPD 480
  481 REAIVHSLTT KESLFSLKGR TCIALGHDEN ISGRKSIDPA KVLYKPTSSN GNWQYVEDDE 540
  541 TFPRVHDVKI SYDDKYVLLM THQGVIDVYD FSGFPSKEEL SKQTVDPKNF LIPRIARLDV 600
  601 GKNMTCISLP LNTTHQGFHR QQISESQHLV LVSLQDNELQ MWDYKENILI QKYFGQKQQH 660
  661 FIIRSCFAYG NKLVMSGSED GKIYIWDRIR GNLVSVLSGH STVMSNSTKP MGKNCNVVAS 720
  721 NPADKEMFAS GGDDGKIKIW KISRN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) FYV10 GID7 GID8 RMD5 VID28 VID30
    View Details Krogan NJ, et al. (2006) FYV10 GID7 GID8 RMD5 VID24 VID28 VID30 YDL176W
    View Details Ho Y, et al. (2002) CCT2 CCT3 CTF19 FYV10 GID7 GID8 HXT7 MOH1 RMD5 SHS1 TFP1 UME1 VID24 VID28 VID30

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ASF1 3829 - low filter Green EM, et al (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data GID7 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..177] deduced N/A No confident structure predictions are available.
    2 View Details [178..570] PSI-BLAST 82.045757 beta1-subunit of the signal-transducing G protein heterotrimer
    3 View Details [571..745] PSI-BLAST 97.39794 Tup1, C-terminal domain


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle