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Protein Overview: CKL4_ARATH

General Information:
Name(s) found: CKL4_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|62996998|gb|AAY24543.1| casein kinase 1-like protein 4 [Arabidopsis thaliana] [NCBI NR]
  • gi|51971985|dbj|BAD44657.1| protein kinase - like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|51970832|dbj|BAD44108.1| protein kinase - like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|51969158|dbj|BAD43271.1| protein kinase - like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|26452831|dbj|BAC43495.1| putative protein kinase [Arabidopsis thaliana] [NCBI NR]
  • gi|25084133|gb|AAN72183.1| protein kinase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|22329008|ref|NP_194615.2| ckl4 (Casein Kinase I-like 4); ATP binding / kinase/ protein kinase/ protein serine/threonine kinase [Arabidopsis thaliana] [NCBI NR]
  • gi|20466530|gb|AAM20582.1| protein kinase-like protein [Arabidopsis thaliana] [NCBI NR]
  • Protein CASEIN KINASE I-LIKE 4 OS=Arabidopsis thaliana GN=CKL4 PE=1 SV=1 [Swiss-Prot]
  • putative protein kinase [Arabidopsis thaliana]gi|20466530|gb|AAM20582.1| protein kinase-like protein [Arabidopsis thaliana]gi|51971985|dbj|BAD44657.1| protein kinase - like protein [Arabidopsis thaliana]gi|51970832|dbj|BAD44108.1| protein kinase - like [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Casein kinase [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: CKL4 | CKL4 (Casein Kinase I-like 4); casein kinase I/ kinase | chr4:14246365-14249203 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • casein kinase 1-like protein 4 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ATP binding / casein kinase I/ kinase/ protein kinase/ protein serine/threonine kinase/ protein-tyrosine kinase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • protein kinase - like protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • protein kinase-like protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative protein kinase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ckl4 | casein kinase I-like 4 | chr4:14246359-14249197 FORWARD LENGTH=414 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • Casein kinase 1-like protein 4 OS=Arabidopsis thaliana GN=ckl4 PE=2 SV=1 [ARATH-contam.fasta]
  • Casein kinase 1-like protein 4 OS=Arabidopsis thaliana GN=CKL4 PE=2 SV=1 [ARATH.fasta.20160308]
    • Organism: Arabidopsis thaliana
    Length: 414 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IDA]
    Biological Process: protein amino acid phosphorylation [IEA]
    Molecular Function: ATP binding [IEA]
    protein kinase activity [IEA]
    protein serine/threonine kinase activity [IEA]
    kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERIIGGKYK LGRKIGGGSF GEIFLATHID TFEIVAVKIE NSKTKHPQLL YEAKLYRTLE  60
   61 GGSGIPRIRW FGVDGTENAL VMDLLGPSLE DLFVYCGRKF SPKTVLMLAD QMLTRIEYVH 120
  121 SKGYLHRDIK PDNFLMGLGR KANQVYLIDF GLAKRYRDAN TNRHIPYREN KNLTGTARYA 180
  181 SCNTHLGIEQ GRRDDLESLG YVLLYFLRGS LPWQGLKAVD KKQKYDKICE KKISTPIEVL 240
  241 CKSHPVEFAS YFHYCHTLTF DQRPDYGFLK RLFRDLFSRE GYEFDYIYDW TIIKYQQSQK 300
  301 TRSQSQAVPG SSNARAIPMD TSNHRGGTKI SHEAQVSDRV RPANASGPSP QINTAVGRSL 360
  361 GFDQVHKNMN MPSSTSLSPA GTSKRNVRPE TSNSGFGSGN KTGGWTSPFM SPGK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..315] PSI-BLAST 74.045757 Casein kinase-1, CK1
    2 View Details [316..414] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.49988294224815 bayes_pls_golite062009
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • kinase activity
    		•  5.3287080791198 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.96052051118534 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • transferase activity
    		•  3.97138602499442 bayes_pls_golite062009
  • acetylcholine receptor activator activity
    		•  3.57683141337465 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • tau-protein kinase activity
    		•  2.37138140221719 bayes_pls_golite062009
  • protein binding
    		•  2.276111749106 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.79921740914853 bayes_pls_golite062009
  • signal transducer activity
    		•  1.79921740914853 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  1.70788499622067 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  1.68012041942855 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.62406554698532 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.50957095777834 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  1.3898059094397 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.38496328649031 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  1.27291233344322 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  1.06443287817895 bayes_pls_golite062009
  • insulin receptor substrate binding
    		•  0.98689034826741 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.913893847407112 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.81943579965027 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.794058505655489 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.775404673285876 bayes_pls_golite062009
  • receptor activity
    		•  0.775180603313375 bayes_pls_golite062009
  • DNA binding
    		•  0.714163549867672 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.568332175782799 bayes_pls_golite062009
  • transcription factor activity
    		•  0.563262875317016 bayes_pls_golite062009
  • phosphoinositide 3-kinase binding
    		•  0.55685381596176 bayes_pls_golite062009
  • peptidase activity
    		•  0.540289770145252 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.499492353295369 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
    		•  0.48345772948903 bayes_pls_golite062009
  • enzyme binding
    		•  0.46284745266176 bayes_pls_golite062009
  • kinase binding
    		•  0.443916188551908 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
    		•  0.37115026509016 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  0.35402045013148 bayes_pls_golite062009
  • axon guidance receptor activity
    		•  0.330635248803668 bayes_pls_golite062009
  • protein kinase binding
    		•  0.285611963740145 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.265003282584135 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.185857185005548 bayes_pls_golite062009
  • growth factor binding
    		•  0.153144089598532 bayes_pls_golite062009
  • actin filament binding
    		•  0.10870608219756 bayes_pls_golite062009
  • protein kinase C activity
    		•  0.0795689006739899 bayes_pls_golite062009
  • phosphatase binding
    		•  0.01281873906014 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle