YRC Public Data Repository - Protein Structure Prediction

Protein:	YNJD_ECOLI
Organism:	Escherichia coli
Length:	217 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YNJD_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|113726386, gi... - gi\|150395538\|ref\|YP_001326005.1\| spermidine/putrescine ABC transporter ATPase subunit [Sinorhizobium...	291.0	[0..2]	[215..23]
gi\|159794850, gi... - pir\|\|A71243 probable maltose/maltodextrin transport ATP-binding protein - Pyrococcus horikoshii, gi\|... gi\|14590136, gi\|... - gi\|3256589\|dbj\|BAA29272.1\| 362aa long hypothetical maltose/maltodextrin transport ATP-binding protei...	290.0	[0..2]	[216..4]
gi\|221236171, gi... - gi\|221236171\|ref\|YP_002518608.1\| spermidine/putrescine transport ATP-binding protein potA [Caulobact... gi\|25384753 - pir\|\|D87637 hypothetical protein CC3134 [imported] - Caulobacter crescentus gi\|16127364, gi\|... - gi\|16127364\|ref\|NP_421928.1\| spermidine/putrescine ABC transporter, ATP-binding protein [Caulobacter...	290.0	[0..1]	[215..14]
gi\|15073645 - gi\|15073645\|emb\|CAC45287.1\| Probable putrescine transport ATP-binding protein [Sinorhizobium melilot... gi\|15964468 - gi\|15964468\|ref\|NP_384821.1\| putrescine ABC transporter ATP-binding protein [Sinorhizobium meliloti ...	290.0	[0..2]	[215..24]
gi\|86607737 - gi\|86607737\|ref\|YP_476499.1\| sulfate ABC transporter, ATP-binding protein [Cyanobacteria bacterium Y... gi\|86556279, gi\|... - gi\|86607737\|ref\|YP_476499.1\| sulfate ABC transporter, ATP-binding protein [Synechococcus sp. JA-2-3B...	288.0	[0..2]	[216..3]
gi\|119720457, gi... - gi\|119720457\|ref\|YP_920952.1\| spermidine/putrescine ABC transporter ATPase subunit [Thermofilum pend...	288.0	[0..2]	[216..4]
gi\|5457621, gi\|1... - gi\|5457621\|emb\|CAB49112.1\| Sugar transport, ABC transporter ATP-binding protein [Pyrococcus abyssi G... gi\|5457621, gi\|7... - pir\|\|A75208 sugar transport ATP-binding protein. PAB2232 - Pyrococcus abyssi (strain Orsay), gi\|5457...	288.0	[0..2]	[216..4]
gi\|89349159, gi\|... - gi\|89362113\|ref\|ZP_01199924.1\| Spermidine/putrescine ABC transporter ATP-binding subunit [Xanthobact...	287.0	[0..1]	[215..29]
gi\|116250536, gi... - gi\|116250536\|ref\|YP_766374.1\| putrescine ABC transporter ATP-binding protein [Rhizobium leguminosaru...	287.0	[0..2]	[215..23]
gi\|77459466, gi\|... - gi\|77459466\|ref\|YP_348973.1\| spermidine/putrescine ABC transporter ATP-binding subunit [Pseudomonas ...	286.0	[0..1]	[216..16]

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Predicted Domain #1

Region A:
Residues: [1-217]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLCVKNVSLR LPESRLLTNV NFTVDKGDIV TLMGPSGCGK STLFSWMIGA LAEQFSCTGE  60
   61 LWLNEQRIDI LPTAQRQIGI LFQDALLFDQ FSVGQNLLLA LPATLKGNAR RNAVNDALER 120
  121 SGLEGAFHQD PATLSGGQRA RVALLRALLA QPKALLLDEP FSRLDVALRD NFRQWVFSEV 180
  181 RALAIPVVQV THDLQDVPAD SSVLDMAQWS ENYNKLR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.69897
Match:	1v43A
Description:	Crystal Structure of ATPase subunit of ABC Sugar Transporter
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
anion transmembrane-transporting ATPase activity	4.71935767060308	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	4.35344629015015	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.4837867129694	bayes_pls_golite062009
ion transmembrane transporter activity	3.35436118751376	bayes_pls_golite062009
phosphate transmembrane-transporting ATPase activity	3.20894563245332	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	3.19399273923292	bayes_pls_golite062009
phosphate transmembrane transporter activity	3.14373643903738	bayes_pls_golite062009
anion transmembrane transporter activity	3.13913638619234	bayes_pls_golite062009
transporter activity	3.10463051760206	bayes_pls_golite062009
cation transmembrane transporter activity	3.08390071341252	bayes_pls_golite062009
transmembrane transporter activity	2.95886887664984	bayes_pls_golite062009
hydrolase activity	2.95296098606221	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	2.9271291809464	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.89122312915795	bayes_pls_golite062009
branched-chain aliphatic amino acid transmembrane transporter activity	2.88795687640992	bayes_pls_golite062009
pyrophosphatase activity	2.81593838944939	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.79724985811732	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.79347973548337	bayes_pls_golite062009
amine-transporting ATPase activity	2.69529191205818	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.67957846350199	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	2.67815672695824	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	2.63419811368692	bayes_pls_golite062009
primary active transmembrane transporter activity	2.61775212528604	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	2.61467977505707	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	2.57552435627908	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	2.57107347424517	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	2.57054427875021	bayes_pls_golite062009
active transmembrane transporter activity	2.50494515048649	bayes_pls_golite062009
ATPase activity	2.44176688200537	bayes_pls_golite062009
ATPase activity, coupled	2.43862163407966	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.40292717311506	bayes_pls_golite062009
amine transmembrane transporter activity	2.29486577878686	bayes_pls_golite062009
metal ion transmembrane transporter activity	2.26365379756656	bayes_pls_golite062009
molybdate ion transmembrane transporter activity	2.04724145339382	bayes_pls_golite062009
molybdate transmembrane-transporting ATPase activity	2.04724145339382	bayes_pls_golite062009
substrate-specific transporter activity	1.91091452720653	bayes_pls_golite062009
amino acid transmembrane transporter activity	1.59627719545436	bayes_pls_golite062009
binding	1.55526868300981	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	1.23799860254751	bayes_pls_golite062009
GTPase activity	1.05341575831759	bayes_pls_golite062009
cation channel activity	0.997064416395892	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
peptide-transporting ATPase activity	0.911425383309011	bayes_pls_golite062009
potassium channel activity	0.843657228494419	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	0.767424210804186	bayes_pls_golite062009
peptide transporter activity	0.73541731084591	bayes_pls_golite062009
voltage-gated cation channel activity	0.688632087597536	bayes_pls_golite062009
protein binding	0.652462335312432	bayes_pls_golite062009
voltage-gated channel activity	0.562664200036023	bayes_pls_golite062009
voltage-gated ion channel activity	0.559798751382976	bayes_pls_golite062009
protein transporter activity	0.496445561359492	bayes_pls_golite062009
catalytic activity	0.458437698837681	bayes_pls_golite062009
ATP binding	0.41092997612902	bayes_pls_golite062009
adenyl ribonucleotide binding	0.385813421701492	bayes_pls_golite062009
adenyl nucleotide binding	0.377870145186619	bayes_pls_golite062009
guanyl nucleotide binding	0.373350189511011	bayes_pls_golite062009
guanyl ribonucleotide binding	0.363151049799385	bayes_pls_golite062009
GTP binding	0.343113158179248	bayes_pls_golite062009
gated channel activity	0.299411774392227	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	0.248918847596573	bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism	0.219473333671469	bayes_pls_golite062009
ion channel activity	0.154779598791225	bayes_pls_golite062009
amino acid-transporting ATPase activity	0.147644650870465	bayes_pls_golite062009
passive transmembrane transporter activity	0.134817721656507	bayes_pls_golite062009
channel activity	0.134817721656507	bayes_pls_golite062009
substrate-specific channel activity	0.126911677161968	bayes_pls_golite062009
cation-transporting ATPase activity	0.0536898657672154	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: