| Protein: | Fps85D-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1325 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Fps85D-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
455.0 | [0..1] | [1318..1] |
|
Region A: Residues: [1-292] |
1 11 21 31 41 51
| | | | | |
1 MGFSSALQSR AAHEALIVRQ DAELRLMETM KRSIQMKAKC DKEYAISLTA VAQQGLKIDR 60
61 ADEMQGSLIS KSWRSYMDEL DHQAKQFKFN AEQLEVVCDK LTHLSQDKRK ARKAYQEEHA 120
121 KIAARLNHLT DEVVRKKSEY QKHLEGYKAL RTRFEENYIK APSRSGRKLD DVRDKYQKAC 180
181 RKLHLTHNEY VLSITEAIEV EKDFRNVLLP GLLEHQQSVQ ESFILLWRNI LQEAAQYGDL 240
241 TADKYKEIQK RIDTVIGSIN PTEEYGEFTE KYKTSPTTPL LFQFDETLIQ DI
|
| Detection Method: |  |
| Confidence: | 26.69897 |
| Match: | 2eflA |
| Description: | No description for 2eflA was found. |
|
Region A: Residues: [293-436] |
1 11 21 31 41 51
| | | | | |
1 PGKLQSSTLT VDNLTVDWLR NRLQELEGAV RDCQEKQMKM IEHVNGGSPV ANGSIISNGS 60
61 NTSNGIQSNK DSLCRQSKDL NALRCQEKQK QKLVDMIKCA LNEVGCEELP SGCDDDLTLE 120
121 QNFIENGYNN EQQRSNSTSS PGLG
|
| Detection Method: | |
| Confidence: | 5.0 |
| Match: | 2tmaA |
| Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [437-537] |
1 11 21 31 41 51
| | | | | |
1 IMNELMRRGG VLTLLRGRGR HFKRKSTPQP ATPMTRSRQG RFNKLQPRSQ SLGSLSVIRD 60
61 GNGPSPARYE PITNHRLRQA ASVHYLGEEI ATSSTNPPDL T
|
| Detection Method: | |
| Confidence: | 2.49 |
| Match: | 1wquA |
| Description: | Solution structure of the human FES SH2 domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [538-738] |
1 11 21 31 41 51
| | | | | |
1 RLRRTQCSML CLGEDEEPVV LASPAPLTQL TAAVLTNTNN NHIYADLELD KKKDTSPSPE 60
61 CKGEQIQPKK EQIRIEINQT APQNSIDAHL DRIDELNRVL DDRLKRTLQP SDDVNAIESA 120
121 EENHIQTRKL AKDPDSQTKR SSSSSSECRS SKDTSHSKKR SLSFSQKSIS NIFSNLKEFS 180
181 KSPLVRMGKN HILNEEQDAK R
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [739-799] |
1 11 21 31 41 51
| | | | | |
1 TQPSQHHHSS GSDCPTNSSS SSSNNNNNNK NTSSNSNHSA SQSTIITSTI TTTITTTTTT 60
61 T
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [800-1325] |
1 11 21 31 41 51
| | | | | |
1 PSKENSRLKF KVPKIQKKSK AIRNTFRSKL LNFQLKRSKP CKQCTKRRRI HPSKSVFDFA 60
61 KEFEVEQPAG SAADEQFCNC PPAGQKPVKP SVQISGHKDH PFESSSGELD ENSDRDIDND 120
121 EEEEDSASDD VLSMKDHCYC VPSLAASISL STNRPLYEEE WFHGVLPREE VVRLLNNDGD 180
181 FLVRETIRNE ESQIVLSVCW NGHKHFIVQT TGEGNFRFEG PPFASIQELI MHQYHSELPV 240
241 TVKSGAILRR PVCRERWELS NDDVVLLERI GRGNFGDVYK AKLKSTKLDV AVKTCRMTLP 300
301 DEQKRKFLQE GRILKQYDHP NIVKLIGICV QKQPIMIVME LVLGGSLLTY LRKNSNGLTT 360
361 RQQMGMCRDA AAGMRYLESK NCIHRDLAAR NCLVDLEHSV KISDFGMSRE EEEYIVSDGM 420
421 KQIPVKWTAP EALNFGKYTS LCDVWSYGIL MWEIFSKGDT PYSGMTNSRA RERIDTGYRM 480
481 PTPKSTPEEM YRLMLQCWAA DAESRPHFDE IYNVVDALIL RLDNSH
|
| Detection Method: | |
| Confidence: | 121.0 |
| Match: | 2h8hA |
| Description: | No description for 2h8hA was found. |
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 3.43994026029707 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| CD8 receptor binding | 3.34636716492159 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 2.9751846707539 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.52531786618214 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.46424348876434 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.37122853419919 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| SH2 domain binding | 2.08937039830657 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 1.9016235206634 | bayes_pls_golite062009 |
| actin binding | 1.87817875565699 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine kinase activity | 1.66669268613198 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| vinculin binding | 1.63216315345235 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| PTB domain binding | 1.56656184134104 | bayes_pls_golite062009 |
| growth factor binding | 1.53863828216563 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 1.42275431028856 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| tubulin binding | 1.13686658158825 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 1.10045286406485 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 1.10045286406485 | bayes_pls_golite062009 |
| cation channel activity | 1.04999722123563 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 0.98689034826741 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| JUN kinase kinase kinase kinase activity | 0.886904175966993 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| actin filament binding | 0.794152600084 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.75189004129952 | bayes_pls_golite062009 |
| microtubule binding | 0.734274677384472 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| insulin binding | 0.546269851452869 | bayes_pls_golite062009 |
| activin binding | 0.510364757301021 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| 3-phosphoinositide-dependent protein kinase binding | 0.372842462336059 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| phosphotyrosine binding | 0.311079584914389 | bayes_pls_golite062009 |
| channel activity | 0.287189255116606 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.287189255116606 | bayes_pls_golite062009 |
| kinase binding | 0.26752427107238 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.261869836686301 | bayes_pls_golite062009 |
| ion channel activity | 0.241519346930618 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| insulin receptor activity | 0.188254408239569 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 0.150740450460731 | bayes_pls_golite062009 |
| JUN kinase kinase kinase activity | 0.0613131034808199 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| cation binding | 0.046173055856133 | bayes_pls_golite062009 |
| metal ion binding | 0.046173055856133 | bayes_pls_golite062009 |
| ion binding | 0.0389662058697694 | bayes_pls_golite062009 |
| protein kinase binding | 0.00674998152095019 | bayes_pls_golite062009 |
