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View Structure Prediction Details

Protein: CE28998
Organism: Caenorhabditis elegans
Length: 789 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE28998.

Description E-value Query
Range		 Subject
Range
gi|187028836, gi... - gi|39584805|emb|CAE67700.1| Hypothetical protein CBG13269 [Caenorhabditis briggsae], gi|187028836|em...
gi|157773863 - gi|157773863|ref|XP_001664997.1| hypothetical protein CBG13269 [Caenorhabditis briggsae AF16]
 504.0 [0..1] [789..1]

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Predicted Domain #1
Region A:
Residues: [1-789] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATKERKRRG KWDTYKAEEA PSLYSGNADK ETSSVPKAAS HNLNGENASS VMTDEFGAKD  60
   61 YRKDMPLKGD FTARPLWVAP DGHIFLESFS PVYKHARDFL IAISEPVCRP QHIHEYQLTA 120
  121 YSLYAAVSVG LQTKDIIEYL ERLSKSQLPK GVITFVQMCT VSYGKVKLVL KHNRYFVESR 180
  181 HSDVMQKLLK DSVIQSCILD DRVQPAQQTE LPAQEKIKFS HGNENEKGVE KDGAAADGTA 240
  241 AAATDGKVPA DIDEFYGKID GDDEEDAEIR NLQLLTFEIK QETIETVQKR CIELEYPLLA 300
  301 EYDFRNDTLN PNLGIDLKPS TTLRPYQEKS LRKMFGNSRA RSGVIVLPCG AGKTLVGVTA 360
  361 VTTVNKRCLV LANSNVSVEQ WRAQFKLWST IQDKQLVRFT REAKDPAPSG ADATKPVVCI 420
  421 STYSMVAYSG RRTLQAEEAM KFIEKQEWGL LLLDEVHTIP AKMFRRVLTI VQAHCKLGLT 480
  481 ATLVREDDKI TDLNFLIGPK IYEANWMELQ KAGHIAKVQC AEVWCPMTSA FYSYYLRSQI 540
  541 ARKLLLAVMN PNKFRICQFL IKFHERRNDK IIVFSDNVFA LKRYAIEMQK PFLYGETSQN 600
  601 ERMKILQNFQ YNPRVNTIFV SKVADTSFDL PEANVLIQIS AHGGSRRQEA QRLGRILRAK 660
  661 KHSTDQFNAF FYSLVSQDTV EMGYSRKRQR FLVNQGYAYK VVNNLPGMEL EDLKLASKES 720
  721 QLQLLQQVLA TSDADAEEED VKEELADGTI RISRREATMA SMSGGQGAQY HSKAKAIAER 780
  781 HPLFKRFRQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.69897
Match: 2eyqA
Description: Crystal structure of Escherichia coli transcription-repair coupling factor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 5.47805400577115 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 4.24230705019135 bayes_pls_golite062009
dATP binding 3.90236137621968 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 3.27883517727923 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 3.1445172484282 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.99059500119562 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
adenyl deoxyribonucleotide binding 2.90098016780049 bayes_pls_golite062009
purine deoxyribonucleotide binding 2.90098016780049 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
deoxyribonuclease activity 2.72222787956584 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
endodeoxyribonuclease activity 2.60873257753475 bayes_pls_golite062009
transporter activity 2.58140740499725 bayes_pls_golite062009
hydrolase activity 2.55157966585974 bayes_pls_golite062009
nucleic acid binding 2.51683451033161 bayes_pls_golite062009
transmembrane transporter activity 2.39695871109024 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
ATPase activity, coupled 2.18396165590908 bayes_pls_golite062009
DNA binding 2.12258000781149 bayes_pls_golite062009
transcription regulator activity 2.09345198747025 bayes_pls_golite062009
endonuclease activity 1.96689197136388 bayes_pls_golite062009
purine ribonucleotide binding 1.85943679361938 bayes_pls_golite062009
ribonucleotide binding 1.85937484083653 bayes_pls_golite062009
purine nucleotide binding 1.8521191028835 bayes_pls_golite062009
nucleotide binding 1.84603132945448 bayes_pls_golite062009
1.75135117904448 bayes_pls_golite062009
helicase activity 1.70242731830224 bayes_pls_golite062009
ATP binding 1.5859264197035 bayes_pls_golite062009
adenyl ribonucleotide binding 1.55520429131224 bayes_pls_golite062009
adenyl nucleotide binding 1.53158018507951 bayes_pls_golite062009
RNA helicase activity 1.42791449104435 bayes_pls_golite062009
RNA-dependent ATPase activity 1.39335733374328 bayes_pls_golite062009
ATP-dependent RNA helicase activity 1.36724390116598 bayes_pls_golite062009
substrate-specific transporter activity 1.29730375126024 bayes_pls_golite062009
structure-specific DNA binding 1.2539059700735 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
kinase activity 1.21578538537164 bayes_pls_golite062009
DNA-dependent ATPase activity 1.2155186842031 bayes_pls_golite062009
ATP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.18669029764243 bayes_pls_golite062009
protein kinase activity 1.12864835254143 bayes_pls_golite062009
double-stranded DNA binding 1.117585097627 bayes_pls_golite062009
transcription elongation regulator activity 1.11383295816593 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.906554174337376 bayes_pls_golite062009
transcription activator activity 0.889929694023098 bayes_pls_golite062009
transcription factor activity 0.887108427603557 bayes_pls_golite062009
motor activity 0.87979065815418 bayes_pls_golite062009
DNA helicase activity 0.72881469450553 bayes_pls_golite062009
RNA binding 0.715902454627085 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.579884353047732 bayes_pls_golite062009
single-stranded DNA binding 0.568457189190858 bayes_pls_golite062009
sequence-specific DNA binding 0.543891899378373 bayes_pls_golite062009
active transmembrane transporter activity 0.434775387083003 bayes_pls_golite062009
microtubule motor activity 0.35554075339843 bayes_pls_golite062009
ion transmembrane transporter activity 0.355466224802969 bayes_pls_golite062009
protein serine/threonine kinase activity 0.345873656782869 bayes_pls_golite062009
mismatched DNA binding 0.31144582840038 bayes_pls_golite062009
primary active transmembrane transporter activity 0.294474570607914 bayes_pls_golite062009
DNA strand annealing activity 0.283577486331079 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.282352478532746 bayes_pls_golite062009
four-way junction helicase activity 0.26252931460003 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.243902356228423 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.220608508617331 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.219533217661421 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.219157471322311 bayes_pls_golite062009
exodeoxyribonuclease V activity 0.185603938981231 bayes_pls_golite062009
nucleotidyltransferase activity 0.181509771587324 bayes_pls_golite062009
protein transporter activity 0.178442534411253 bayes_pls_golite062009
transferase activity 0.168270793917772 bayes_pls_golite062009
guanyl nucleotide binding 0.132012746266431 bayes_pls_golite062009
guanyl ribonucleotide binding 0.121792392568515 bayes_pls_golite062009
GTP binding 0.119757493758508 bayes_pls_golite062009
GTPase activity 0.105546189348878 bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism 0.0263010404932493 bayes_pls_golite062009
cation transmembrane transporter activity 0.0254369227200564 bayes_pls_golite062009
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