YRC Public Data Repository - Protein Structure Prediction

Protein:	ran-1
Organism:	Caenorhabditis elegans
Length:	215 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ran-1.

Description	E-value	Query Range	Subject Range
rab-1 - RAS-related protein status:Confirmed UniProt:Q9UAQ6 protein_id:AAC69218.1	204.0	[0..1]	[203..1]
CRE16067, FL81_1... - RP15185 WBGene00061078 locus:Cre-rab-1 status:Confirmed, null gi\|157761211 - gi\|157761211\|ref\|XP_001672948.1\| Hypothetical protein CBG01077 [Caenorhabditis briggsae AF16] gi\|39588485, gi\|... - gi\|39588485\|emb\|CAE58008.1\| Hypothetical protein CBG01077 [Caenorhabditis briggsae], gi\|187038224\|em...	204.0	[0..1]	[203..1]
gi\|114675154 - gi\|114675154\|ref\|XP_001147785.1\| PREDICTED: similar to GTP-binding protein RAB11B [Pan troglodytes]	203.0	[0..3]	[205..135]
gi\|109081641 - gi\|109081641\|ref\|XP_001103732.1\| PREDICTED: similar to RAB11a, member RAS oncogene family [Macaca mu...	202.0	[0..3]	[206..93]
gi\|303734, gi\|738942 - gi\|738942\|prf\|\|2001457K GTP-binding protein, gi\|303734\|dbj\|BAA02118.1\| GTP-binding protein [Pisum sa... gi\|1098293, gi\|4... - pir\|\|S41430 GTP-binding protein, ras-like (clone vfa-ypt1) - fava bean, gi\|452359\|emb\|CAA82707.1\| g...	201.0	[0..3]	[205..2]
gi\|58261356, gi\|... - gi\|58261356\|ref\|XP_568088.1\| ras-related protein ypt1 [Cryptococcus neoformans var. neoformans JEC21... gi\|134090963, gi... - gi\|50256143\|gb\|EAL18870.1\| hypothetical protein CNBI1310 [Cryptococcus neoformans var. neoformans B-...	201.0	[0..1]	[202..1]
gi\|71019499, gi\|... - gi\|71019499\|ref\|XP_759980.1\| GTP-binding protein Ypt1 [Ustilago maydis 521], ref\|XP_401448.1\| YPT1_N...	201.0	[0..1]	[203..1]
gi\|148230336, gi... - gi\|27924279\|gb\|AAH45014.1\| Rab1-prov protein [Xenopus laevis], gi\|148230336\|ref\|NP_001080138.1\| RAB1... gi\|52345478, gi\|... - gi\|52345478\|ref\|NP_001004787.1\| RAB1A, member RAS oncogene family [Xenopus (Silurana) tropicalis], g...	200.0	[0..1]	[203..1]
RIC1_ORYSJ - Ras-related protein RIC1 OS=Oryza sativa subsp. japonica GN=RIC1 PE=2 SV=2 gi\|125526416 - gi\|125526416\|gb\|EAY74530.1\| hypothetical protein OsI_02420 [Oryza sativa Indica Group] RIC1_ORYSA - Ras-related protein RIC1 - Oryza sativa (Rice)	200.0	[0..3]	[204..2]

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Predicted Domain #1

Region A:
Residues: [1-215]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGGDGIPTF KLVLVGDGGT GKTTFVKRHL TGEFEKKYVA TLGVEVHPLV FHTNRGQIRF  60
   61 NVWDTAGQEK FGGLRDGYYI QGQCAIIMFD VTARVTYKNV PNWHRDLARV CENIPIVLCG 120
  121 NKVDVKDRKV KAKTITFHRK KNLQYYDISA KSNYNFEKPF LWLARKLLGD PNLEFVAMPA 180
  181 LAPPEVQMDP AMIAEYEKDL DNAAKADLPD DDDDL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.045757
Match:	1byuA
Description:	Ran
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
microtubule motor activity	4.51968578934603	bayes_pls_golite062009
motor activity	4.04927796049806	bayes_pls_golite062009
signal recognition particle binding	3.10924684520019	bayes_pls_golite062009
transporter activity	3.10463051760206	bayes_pls_golite062009
transmembrane transporter activity	2.95886887664984	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.95079405147356	bayes_pls_golite062009
pyrophosphatase activity	2.87427509025394	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.85499564954033	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.85178667290149	bayes_pls_golite062009
DNA-dependent ATPase activity	2.72462789867829	bayes_pls_golite062009
tubulin binding	2.67743463093593	bayes_pls_golite062009
hydrolase activity	2.65461298232951	bayes_pls_golite062009
binding	2.64537357529343	bayes_pls_golite062009
primary active transmembrane transporter activity	2.61775212528604	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	2.61467977505707	bayes_pls_golite062009
microtubule binding	2.59155206524122	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	2.57552435627908	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	2.57107347424517	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	2.57054427875021	bayes_pls_golite062009
microfilament motor activity	2.51786963027655	bayes_pls_golite062009
nucleic acid binding	2.51683451033161	bayes_pls_golite062009
active transmembrane transporter activity	2.50494515048649	bayes_pls_golite062009
ATPase activity, coupled	2.43862163407966	bayes_pls_golite062009
cytoskeletal protein binding	2.4101693596493	bayes_pls_golite062009
ATPase activity	2.39535714892224	bayes_pls_golite062009
G-protein coupled receptor activity	2.3505608190884	bayes_pls_golite062009
actin binding	2.2973522188675	bayes_pls_golite062009
DNA helicase activity	2.2817164193758	bayes_pls_golite062009
DNA binding	2.12258000781149	bayes_pls_golite062009
transcription regulator activity	2.09345198747025	bayes_pls_golite062009
ribonucleoprotein binding	2.04103162399905	bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism	1.95782378818812	bayes_pls_golite062009
substrate-specific transporter activity	1.91091452720653	bayes_pls_golite062009
guanyl nucleotide binding	1.89320355239381	bayes_pls_golite062009
guanyl ribonucleotide binding	1.88721318481223	bayes_pls_golite062009
ATP-dependent DNA helicase activity	1.88455339138556	bayes_pls_golite062009
GTP binding	1.87900088157196	bayes_pls_golite062009
purine ribonucleotide binding	1.85943679361938	bayes_pls_golite062009
ribonucleotide binding	1.85937484083653	bayes_pls_golite062009
purine nucleotide binding	1.8521191028835	bayes_pls_golite062009
nucleotide binding	1.84603132945448	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	1.81972511638668	bayes_pls_golite062009
kinase activity	1.80889641165674	bayes_pls_golite062009
protein transporter activity	1.71214667007262	bayes_pls_golite062009
helicase activity	1.70242731830224	bayes_pls_golite062009
GTPase activity	1.6309422514633	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.60386625568858	bayes_pls_golite062009
ATP binding	1.5859264197035	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.56325751172863	bayes_pls_golite062009
adenyl ribonucleotide binding	1.55520429131224	bayes_pls_golite062009
adenyl nucleotide binding	1.53158018507951	bayes_pls_golite062009
RNA helicase activity	1.42791449104435	bayes_pls_golite062009
RNA-dependent ATPase activity	1.39335733374328	bayes_pls_golite062009
plus-end-directed microtubule motor activity	1.38366133153678	bayes_pls_golite062009
ATP-dependent RNA helicase activity	1.36724390116598	bayes_pls_golite062009
apolipoprotein receptor activity	1.31055516357904	bayes_pls_golite062009
syntaxin-13 binding	1.31055516357904	bayes_pls_golite062009
apolipoprotein A-I binding	1.31055516357904	bayes_pls_golite062009
apolipoprotein A-I receptor activity	1.31055516357904	bayes_pls_golite062009
protein-DNA loading ATPase activity	1.29640539057136	bayes_pls_golite062009
actin filament binding	1.28204719195916	bayes_pls_golite062009
transmembrane receptor activity	1.26314334516725	bayes_pls_golite062009
protein binding	1.22129154759482	bayes_pls_golite062009
receptor activity	1.20313362488821	bayes_pls_golite062009
ATP-dependent helicase activity	1.19311444180077	bayes_pls_golite062009
purine NTP-dependent helicase activity	1.19311444180077	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.14475274823167	bayes_pls_golite062009
signal transducer activity	1.13474466330485	bayes_pls_golite062009
molecular transducer activity	1.13474466330485	bayes_pls_golite062009
protein kinase activity	1.12864835254143	bayes_pls_golite062009
DNA clamp loader activity	1.12431517057397	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	1.11794390756322	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
ion transmembrane transporter activity	0.977237423302079	bayes_pls_golite062009
actin-dependent ATPase activity	0.92105578610354	bayes_pls_golite062009
transcription activator activity	0.889929694023098	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	0.889480122725603	bayes_pls_golite062009
transcription factor activity	0.887108427603557	bayes_pls_golite062009
transferase activity	0.871779313294914	bayes_pls_golite062009
structure-specific DNA binding	0.782430219754236	bayes_pls_golite062009
microtubule plus-end binding	0.673980113049624	bayes_pls_golite062009
steroid hormone receptor binding	0.647625526012423	bayes_pls_golite062009
double-stranded DNA binding	0.6071273686445	bayes_pls_golite062009
telomeric DNA binding	0.60010060632866	bayes_pls_golite062009
sterol transporter activity	0.57614280790431	bayes_pls_golite062009
cation transmembrane transporter activity	0.557919489256916	bayes_pls_golite062009
sequence-specific DNA binding	0.543891899378373	bayes_pls_golite062009
kinetochore binding	0.505370954958131	bayes_pls_golite062009
protein transmembrane transporter activity	0.46552249844591	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	0.444874730945263	bayes_pls_golite062009
	0.442119153778711	bayes_pls_golite062009
hormone receptor binding	0.351501100511918	bayes_pls_golite062009
protein serine/threonine kinase activity	0.345873656782869	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.325013574811283	bayes_pls_golite062009
peptide binding	0.304703625340488	bayes_pls_golite062009
nuclear hormone receptor binding	0.246160342138071	bayes_pls_golite062009
structural constituent of ribosome	0.208665086324262	bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity	0.12351419478929	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.123304946374679	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.0775601177068852	bayes_pls_golite062009
histone acetyltransferase activity	0.0320943071400439	bayes_pls_golite062009
lysine N-acetyltransferase activity	0.0320943071400439	bayes_pls_golite062009
RNA binding	0.0261282189186349	bayes_pls_golite062009
structural constituent of cytoskeleton	0.0111338193708552	bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	0.00571427458217011	bayes_pls_golite062009
macromolecule transmembrane transporter activity	0.00571427458217011	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: