| Protein: | shark-PA |
| Organism: | Drosophila melanogaster |
| Length: | 939 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for shark-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
482.0 | [0..1] | [937..1] |
|
Region A: Residues: [1-355] |
1 11 21 31 41 51
| | | | | |
1 MSRDSDPMKW YHGNLSREAA DELLKQGYED GTFLVRESST AAGDFVLSLL CQGEVCHYQV 60
61 RRHGGEDAFF SIDDKVQTKI LHGLDTLVDY YQQAANGLPT KLTVPLIRDL PPHNTRSHGV 120
121 TNLLHRATSK NESKVVFELL KCGYRNFDAK NQDGQTALHL AALHSDEDIL KHLLNAKVQV 180
181 NSSDSFGCQP LHYAARSKPA SFIRTLISAQ ANVQGRNIDN GYVPLHEAAK HGNLEAVQEL 240
241 LLAEAPPLPR TSSGEFPFDL AKEAGQTAVE EFLLNYKLPP ANTTRDQWYH GTLTREEAVA 300
301 ILKKHAKELL AKQPEVDTSG CFLVRYSESP AASGLVLTLL CDQVVKNFRI SQADL
|
| Detection Method: |  |
| Confidence: | 49.221849 |
| Match: | 1n11A |
| Description: | Ankyrin-R |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cytoskeletal protein binding | 3.56691760558785 | bayes_pls_golite062009 |
| protein binding | 2.69918165732603 | bayes_pls_golite062009 |
| actin binding | 2.66339417940702 | bayes_pls_golite062009 |
| binding | 2.60916417202222 | bayes_pls_golite062009 |
| actin filament binding | 1.79702615462276 | bayes_pls_golite062009 |
| protein kinase activity | 1.44085162459605 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.24901082343235 | bayes_pls_golite062009 |
| signal transducer activity | 1.2375987667709 | bayes_pls_golite062009 |
| molecular transducer activity | 1.2375987667709 | bayes_pls_golite062009 |
| receptor activity | 1.22857731988464 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.22209007484238 | bayes_pls_golite062009 |
| kinase activity | 1.20122575201235 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.10325771560525 | bayes_pls_golite062009 |
| transcription factor binding | 0.84590123339816 | bayes_pls_golite062009 |
| transporter activity | 0.782432203646924 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.653190853243002 | bayes_pls_golite062009 |
| transcription regulator activity | 0.589753112911856 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.515634991066501 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.375391185084903 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.3210142108162 | bayes_pls_golite062009 |
| transcription activator activity | 0.295016294965448 | bayes_pls_golite062009 |
| transferase activity | 0.291085370218412 | bayes_pls_golite062009 |
| nucleic acid binding | 0.280340492381105 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.238966076323951 | bayes_pls_golite062009 |
| DNA binding | 0.139886855398905 | bayes_pls_golite062009 |
| transcription repressor activity | 0.108244697820437 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.0675641359654993 | bayes_pls_golite062009 |
| channel activity | 0.0675641359654993 | bayes_pls_golite062009 |
|
Region A: Residues: [356-463] |
1 11 21 31 41 51
| | | | | |
1 YQNGNKVQSG GSKFLYIDDG PYWPSVEHLI AHFMRFSYGL PVSLKYPVPP QPKPEVPSFA 60
61 TIPRSNMKPK AASPATPPTP VSPHSHHQHP HVPALTITKK KQKENSSS
|
| Detection Method: | |
| Confidence: | 3.17 |
| Match: | 1qcfA |
| Description: | Hemapoetic cell kinase Hck; Hemopoetic cell kinase Hck; Haemopoetic cell kinase Hck |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [464-939] |
1 11 21 31 41 51
| | | | | |
1 MFNTLRLTSP KKALFDMNSL RKNKSKGKRS DSESSVSGSL AGTEQELQAA APMLKSLSFS 60
61 TEFSTFNADG VTGSGAAAAG EVYNVPRNNT PIEIDLPPIA QKTEAEVEYF TKSDVAIERE 120
121 RAGQWIGNGY QPTMDVLSLL DQQIKAPAVA RLNSLGPNAS TESEMASYLH RKCSGTPSTP 180
181 SATEVEAAKL RFFIEPEKLV LDREIGHGEF GSVHSGWLLR KSGAGEESRL EVAIKMLSDE 240
241 HSNKQEFLRE ASVMMRLEHK CIVRLIGIAK GEMLMMVQEL APLGSMLQYI LDHGHEITAN 300
301 AELKVWASQI ACGMHYLESQ HFVHRDLAAR NILLTARHQA KISDFGMSRS LRPGSTEYQF 360
361 TQGGRWPIRW YAPESFNLGI FSHASDVWSF GVTIWEMFSL GAPPYGEISN VDAIKLVDSG 420
421 ERLPQPNLCP AYIYAVMQSC WKERPKDRPT FVYLTEFFAR DPDYQNLPEL VQTVHI
|
| Detection Method: | |
| Confidence: | 96.69897 |
| Match: | 2h8hA |
| Description: | No description for 2h8hA was found. |
| Term | Confidence | Notes |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.04467222534257 | bayes_pls_golite062009 |
| kinase activity | 4.85903980916957 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.63692708178478 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| JUN kinase kinase kinase kinase activity | 3.31264000585107 | bayes_pls_golite062009 |
| transferase activity | 3.26787750561728 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 2.9751846707539 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| actin binding | 2.42703012169921 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.38494443043195 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| actin filament binding | 1.68048469859634 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine kinase activity | 1.66669268613198 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| vinculin binding | 1.63216315345235 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| growth factor binding | 1.53863828216563 | bayes_pls_golite062009 |
| integrin binding | 1.44154155381408 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 1.10045286406485 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 1.10045286406485 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 0.95914323793919 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 0.91037901281763 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.75189004129952 | bayes_pls_golite062009 |
| transporter activity | 0.710766490066447 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.610230065465794 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.60324822483033 | bayes_pls_golite062009 |
| activin binding | 0.510364757301021 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.385603245903806 | bayes_pls_golite062009 |
| kinase binding | 0.26752427107238 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.152203945257581 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| MAP kinase kinase kinase kinase activity | 0.01826424351081 | bayes_pls_golite062009 |
| protein kinase binding | 0.00674998152095019 | bayes_pls_golite062009 |
