| Protein: | gi|7303012, gi|2... |
| Organism: | Drosophila melanogaster |
| Length: | 1086 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7303012, gi|2....
| Description | E-value | Query Range |
Subject Range |
|
|
1023.0 | [0..1] | [1086..1] |
|
Region A: Residues: [1-419] |
1 11 21 31 41 51
| | | | | |
1 MSAKAITEAS GKDILNRHLN THGAGAATCR FSTVNSTTDW SKLAVDHPWL LTTPLVCKPD 60
61 QLIKRRGKLG LIGVKKNFEQ VKQWIGERLN KDQKIGNAVG KLRNFIIEPF VPHTDAEEMY 120
121 VCIYSHRAAD TILFYHQGGV DIGDVDAKAV KLDVPVNSSL SLADVKSKLL KEVKDAGTKE 180
181 RIAKFVSALY TTYVDLYFTY LEINPLVVTA DNLYILDLAA KLDSTADFIC RPKWGEIDYP 240
241 PPFGRDAYPE EAYIADLDAK SGASLKLTIL NRNGRIWTMV AGGGASVIYS DTICDLGGAS 300
301 ELANYGEYSG APSEQQTYEY AKTILNLMTS SPKHPDGKVL ITGGGIANFT NVAATFQGII 360
361 TALREFQPKL VEHNVSIFVR RAGPNYQEGL RKMRDFGSTL GIPLHVFGPE THMTAICGM
|
| Detection Method: |  |
| Confidence: | 102.0 |
| Match: | 1jkjB |
| Description: | Succinyl-CoA synthetase, beta-chain, C-terminal domain; Succinyl-CoA synthetase, beta-chain, N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| succinate-CoA ligase activity | 11.5979130191209 | bayes_pls_golite062009 |
| CoA-ligase activity | 10.4192804448897 | bayes_pls_golite062009 |
| acid-thiol ligase activity | 10.243481928473 | bayes_pls_golite062009 |
| ligase activity, forming carbon-sulfur bonds | 9.48706872092269 | bayes_pls_golite062009 |
| succinate-CoA ligase (ADP-forming) activity | 9.35325976720833 | bayes_pls_golite062009 |
| succinate-CoA ligase (GDP-forming) activity | 6.10836030777262 | bayes_pls_golite062009 |
| ATP citrate synthase activity | 6.07828121800931 | bayes_pls_golite062009 |
| citrate (pro-3S)-lyase activity | 5.30284195415066 | bayes_pls_golite062009 |
| CoA carboxylase activity | 4.07446700881636 | bayes_pls_golite062009 |
| acetyl-CoA carboxylase activity | 3.99316522494514 | bayes_pls_golite062009 |
| ligase activity, forming carbon-carbon bonds | 3.81289459554571 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 3.35963055171077 | bayes_pls_golite062009 |
| carbamoyl-phosphate synthase activity | 2.72598634080471 | bayes_pls_golite062009 |
| carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity | 2.64774423341735 | bayes_pls_golite062009 |
| biotin carboxylase activity | 2.54447190719035 | bayes_pls_golite062009 |
| ligase activity | 2.30626698552338 | bayes_pls_golite062009 |
| oxo-acid-lyase activity | 2.241458285404 | bayes_pls_golite062009 |
| catalytic activity | 1.90735517755117 | bayes_pls_golite062009 |
| phosphoribosylaminoimidazole carboxylase activity | 1.73669882098773 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer | 1.34604636411023 | bayes_pls_golite062009 |
| phosphoribosylamine-glycine ligase activity | 1.23437256414757 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 1.10474980073192 | bayes_pls_golite062009 |
| carbon-nitrogen ligase activity, with glutamine as amido-N-donor | 1.04673851330289 | bayes_pls_golite062009 |
| nucleotide binding | 0.604878609358233 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.6001056330562 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.585676018122244 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.585256446905581 | bayes_pls_golite062009 |
| acetyltransferase activity | 0.354495767382723 | bayes_pls_golite062009 |
| glutathione synthase activity | 0.158287661667506 | bayes_pls_golite062009 |
|
Region A: Residues: [420-720] |
1 11 21 31 41 51
| | | | | |
1 ALGKRPIPQT ASVEFSTANF LLPGGQQAQA DLKAASDASE ALGSGSADEA DSAGISGAQR 60
61 NGSSLNRKFF SNTTKAIVWG MQQRAVQRDE PSVVAMVYPF TGDHKQKYYW GHKEILIPVY 120
121 KKMSDAIHKH KEVDVMVNFA SMRSAYESTL EVLEFPQIRT VAIIAEGIPE NMTRKLIIEA 180
181 DKKGVAIIGP ATVGGVKPGC FKIGNTGGML DNILHSKLYR PGSVAYVSRS GGMSNELNNI 240
241 ISKATDGVIE GIAIGGDRYP GSTFMDHILR YQADPETKLI VLLGEVGGTE EYDVCAALKD 300
301 G
|
| Detection Method: | |
| Confidence: | 93.69897 |
| Match: | 1jkjA |
| Description: | Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain; Succinyl-CoA synthetase, alpha-chain, C-terminal domain |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| succinate-CoA ligase activity | 4.98013776954984 | bayes_pls_golite062009 |
| CoA-ligase activity | 4.35815624912718 | bayes_pls_golite062009 |
| acid-thiol ligase activity | 4.2282982893826 | bayes_pls_golite062009 |
| ligase activity, forming carbon-sulfur bonds | 3.82878743369312 | bayes_pls_golite062009 |
| malate dehydrogenase activity | 3.73899222825747 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 3.18548497718796 | bayes_pls_golite062009 |
| succinate-CoA ligase (ADP-forming) activity | 3.05087440872447 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 2.56635944108218 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 2.56237767568509 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.3793692436067 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.15364185593759 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.85842298395473 | bayes_pls_golite062009 |
| catalytic activity | 1.79741889688267 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.74270988861575 | bayes_pls_golite062009 |
| fatty acid synthase activity | 1.23679054027553 | bayes_pls_golite062009 |
| methylenetetrahydrofolate dehydrogenase activity | 0.974298363844148 | bayes_pls_golite062009 |
| oxidoreductase activity | 0.9367410227151 | bayes_pls_golite062009 |
| methenyltetrahydrofolate cyclohydrolase activity | 0.696602339330799 | bayes_pls_golite062009 |
| 3-oxoacyl-[acyl-carrier-protein] reductase activity | 0.604742541607263 | bayes_pls_golite062009 |
| DNA binding | 0.525227236870065 | bayes_pls_golite062009 |
| nucleic acid binding | 0.459537641913493 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.444544079187632 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.444104594263908 | bayes_pls_golite062009 |
| malic enzyme activity | 0.431922445809582 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on CH-OH group of donors | 0.418775403210681 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.386364402115347 | bayes_pls_golite062009 |
| nucleotide binding | 0.327349935545314 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 0.32207755075663 | bayes_pls_golite062009 |
| transcription regulator activity | 0.152651308844322 | bayes_pls_golite062009 |
| malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity | 0.120195861875768 | bayes_pls_golite062009 |
| alcohol dehydrogenase (NAD) activity | 0.00644214957417527 | bayes_pls_golite062009 |
|
Region A: Residues: [721-1086] |
1 11 21 31 41 51
| | | | | |
1 RITKPLVAWC IGTCASMFTS EVQFGHAGSC ANSDRETATA KNKGLRDAGA YVPDSFDTLG 60
61 ELIHHVYGEL VKTGRVVPKE EVPPPTVPMD YSWARELGLI RKPASFMTSI CDERGQELIY 120
121 AGMPISEVLS KDVGIGGVIS LLWFQRCLPS YVCKFFEMCL MVTADHGPAV SGAHNTIVCA 180
181 RAGKDLVSSV VSGLLTIGDR FGGALDGSAR QFSEAYDTNL HPMEFVNKMR KEGKLILGIG 240
241 HRVKSINNPD VRVKIIKEFV LENFPACPLL KYALEVEKIT TNKKPNLILN VDGVIATAFV 300
301 DMLRNSGSFT SEEAQEYINV GAINSLFVLG RSIGFIGHYM DQKRLKQGLY RHPWDDISYV 360
361 IPEQYN
|
| Detection Method: | |
| Confidence: | 100.0 |
| Match: | 1k3pA |
| Description: | Citrate synthase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| citrate (Si)-synthase activity | 5.74736490002685 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer | 5.63245943049967 | bayes_pls_golite062009 |
| oxo-acid-lyase activity | 3.68894211625793 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups | 2.88522337475651 | bayes_pls_golite062009 |
| catalytic activity | 2.51855037019879 | bayes_pls_golite062009 |
| transferase activity | 2.22659761972612 | bayes_pls_golite062009 |
