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Catalysis of the reaction between succinate and CoA to form succinyl-CoA. Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate. Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA. Catalysis of the ligation of an acid and a thiol via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: succinate-CoA ligase (ADP-forming) activity
Acc: GO:0004775
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate.
Synonyms:
  • succinate thiokinase activity
  • A-STK (adenin nucleotide-linked succinate thiokinase)
  • succinyl-CoA synthetase activity
  • succinate:CoA ligase (ADP-forming) activity
  • succinyl coenzyme A synthetase
  • succinic thiokinase
  • succinyl coenzyme A synthetase (adenosine diphosphate-forming) activity
  • A-SCS
  • succinyl-CoA synthetase (ADP-forming) activity
Proteins in PDR annotated with:
   This term: 45 [Search]
   Term or descendants: 45 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004775 - succinate-CoA ligase (ADP-forming) activity (interactive image map)
YRC Informatics Platform - Version 3.0
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