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Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer. Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: citrate (Si)-synthase activity
Acc: GO:0004108
Aspect: Molecular Function
Desc: Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group.
Synonyms:
  • citrate condensing enzyme activity
  • citrate oxaloacetate-lyase ((pro-3S)-CH2COO-rightacetyl-CoA)
  • citrate oxaloacetate-lyase [(pro-3S)-CH2COOrightacetyl-CoA]
  • citrate oxaloacetate-lyase, CoA-acetylating activity
  • citrogenase activity
  • citrate synthetase activity
  • (R)-citric synthase activity
  • oxaloacetate transacetase activity
  • acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming]
  • oxalacetic transacetase activity
  • citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA) activity
  • citric synthase activity
  • condensing enzyme activity
  • citrate synthase activity
  • citric-condensing enzyme activity
Proteins in PDR annotated with:
   This term: 32 [Search]
   Term or descendants: 32 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004108 - citrate (Si)-synthase activity (interactive image map)
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