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Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the reaction: ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: glutathione synthase activity
Acc: GO:0004363
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione.
Synonyms:
  • GSH synthetase activity
  • glutathione synthetase activity
  • gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)
Proteins in PDR annotated with:
   This term: 21 [Search]
   Term or descendants: 21 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004363 - glutathione synthase activity (interactive image map)
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