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Catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6. Catalysis of the reaction: ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N1-(5-phospho-D-ribosyl)glycinamide. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: phosphoribosylamine-glycine ligase activity
Acc: GO:0004637
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N1-(5-phospho-D-ribosyl)glycinamide.
Synonyms:
  • glycinamide ribonucleotide synthetase activity
  • phosphoribosylglycineamide synthetase activity
  • 5-phospho-D-ribosylamine:glycine ligase (ADP-forming)
  • 2-amino-N-ribosylacetamide 5'-phosphate kinosynthase activity
  • 5'-phosphoribosylglycinamide synthetase activity
  • GARS activity
  • glycineamide ribonucleotide synthetase activity
  • GAR
  • GAR synthetase activity
  • phosphoribosylglycinamide synthetase activity
Proteins in PDR annotated with:
   This term: 20 [Search]
   Term or descendants: 20 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004637 - phosphoribosylamine-glycine ligase activity (interactive image map)
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