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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Cdc10. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 6 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARC1
  • cytoplasm
  • methionyl glutamyl tRNA synthetase complex
  • tRNA aminoacylation for protein translation
  • tRNA export from nucleus
  • tRNA binding
  • CDC10
  • cellular bud neck septin ring
  • axial cellular bud site selection
  • bipolar cellular bud site selection
  • cell morphogenesis
  • conjugation with cellular fusion
  • cellular cell wall organization
  • cytokinesis
  • cell morphogenesis involved in conjugation with cellular fusion
  • ascospore wall assembly
  • GTPase activity
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • CDC11
  • cellular bud neck septin ring
  • prospore membrane
  • ascospore wall
  • mating projection base
  • axial cellular bud site selection
  • cell morphogenesis
  • conjugation with cellular fusion
  • cellular cell wall organization
  • cytokinesis
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • CDC12
  • cellular bud neck septin ring
  • cytoplasm
  • axial cellular bud site selection
  • bipolar cellular bud site selection
  • cell morphogenesis
  • conjugation with cellular fusion
  • cellular cell wall organization
  • cytokinesis
  • GTPase activity
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • CDC3
  • cellular bud neck septin ring
  • prospore membrane
  • ascospore wall
  • mating projection base
  • axial cellular bud site selection
  • cell morphogenesis
  • cellular cell wall organization
  • cytokinesis
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • LPD1
  • mitochondrial pyruvate dehydrogenase complex
  • mitochondrial oxoglutarate dehydrogenase complex
  • mitochondrion
  • glycine cleavage complex
  • mitochondrial nucleoid
  • acetyl-CoA biosynthetic process from pyruvate
  • leucine catabolic process
  • valine catabolic process
  • L-serine biosynthetic process
  • isoleucine catabolic process
  • glycine catabolic process
  • oxoglutarate dehydrogenase (succinyl-transferring) activity
  • pyruvate dehydrogenase (acetyl-transferring) activity
  • glycine dehydrogenase (decarboxylating) activity
  • dihydrolipoyl dehydrogenase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cellular bud neck septin ring 2.8932E-11 6 9 4 6292
    cleavage apparatus septin structure 2.8932E-11 6 9 4 6292
    cellular bud neck septin structure 2.8932E-11 6 9 4 6292
    septin cytoskeleton 3.1295E-10 6 15 4 6292
    septin ring 3.1295E-10 6 15 4 6292
    cell division site part 4.0114E-9 6 27 4 6292
    cell division site 4.0114E-9 6 27 4 6292
    cell cortex part 7.4599E-7 6 96 4 6292
    cell cortex 1.2451E-6 6 109 4 6292
    cellular bud neck 2.4513E-6 6 129 4 6292
    cellular bud 6.7281E-6 6 166 4 6292
    site of polarized growth 7.0577E-6 6 168 4 6292
    cytoskeletal part 1.4423E-5 6 201 4 6292
    mating projection base 1.5882E-5 6 7 2 6292
    cytoskeleton 1.92E-5 6 216 4 6292
    spore wall 3.399E-5 6 10 2 6292
    ascospore wall 3.399E-5 6 10 2 6292
    prospore membrane 1.2867E-4 6 19 2 6292
    intracellular immature spore 1.2867E-4 6 19 2 6292
    ascospore-type prospore 1.2867E-4 6 19 2 6292
    non-membrane-bounded organelle 4.2731E-4 6 959 5 6292
    intracellular non-membrane-bounded organelle 4.2731E-4 6 959 5 6292
    cell projection part 6.4156E-4 6 42 2 6292
    cell projection 8.7368E-4 6 49 2 6292
    mating projection 8.7368E-4 6 49 2 6292
    mitochondrial oxoglutarate dehydrogenase complex 2.8585E-3 6 3 1 6292
    oxoglutarate dehydrogenase complex 2.8585E-3 6 3 1 6292
    cytoplasmic part 3.7539E-3 6 2482 6 6292
    methionyl glutamyl tRNA synthetase complex 3.8098E-3 6 4 1 6292
    fungal-type cell wall 3.9607E-3 6 105 2 6292
    cell wall 4.0352E-3 6 106 2 6292
    external encapsulating structure 4.0352E-3 6 106 2 6292
    pyruvate dehydrogenase complex 5.7102E-3 6 6 1 6292
    glycine cleavage complex 5.7102E-3 6 6 1 6292
    mitochondrial pyruvate dehydrogenase complex 5.7102E-3 6 6 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    axial cellular bud site selection 5.426E-9 6 29 4 6292
    cellular bud site selection 2.5985E-7 6 74 4 6292
    cytokinesis, site selection 2.5985E-7 6 74 4 6292
    cell cycle cytokinesis 3.5663E-7 6 80 4 6292
    establishment of cell polarity 4.3463E-7 6 84 4 6292
    establishment or maintenance of cell polarity 4.5598E-7 6 85 4 6292
    cell budding 5.7469E-7 6 90 4 6292
    asexual reproduction 5.7469E-7 6 90 4 6292
    cytokinetic process 6.2811E-7 6 92 4 6292
    cytokinesis 1.389E-6 6 112 4 6292
    cell morphogenesis 2.1601E-6 6 125 4 6292
    cellular component morphogenesis 3.2129E-6 6 138 4 6292
    cell division 3.9173E-6 6 145 4 6292
    cell wall organization 7.9341E-6 6 173 4 6292
    external encapsulating structure organization 7.9341E-6 6 173 4 6292
    cellular cell wall organization 7.9341E-6 6 173 4 6292
    cell wall organization or biogenesis 1.6526E-5 6 208 4 6292
    cellular cell wall organization or biogenesis 1.6526E-5 6 208 4 6292
    reproduction of a single-celled organism 1.9555E-5 6 217 4 6292
    anatomical structure morphogenesis 3.8238E-5 6 257 4 6292
    anatomical structure development 4.0034E-5 6 260 4 6292
    cellular developmental process 5.0692E-5 6 276 4 6292
    reproduction 1.0008E-4 6 328 4 6292
    developmental process 1.0373E-4 6 331 4 6292
    conjugation with cellular fusion 1.4656E-4 6 125 3 6292
    conjugation 1.5008E-4 6 126 3 6292
    multi-organism process 2.1868E-4 6 143 3 6292
    bipolar cellular bud site selection 4.1945E-4 6 34 2 6292
    cell cycle process 4.8022E-4 6 490 4 6292
    cell cycle 6.2738E-4 6 525 4 6292
    sexual reproduction 9.229E-4 6 233 3 6292
    valine catabolic process 9.5359E-4 6 1 1 6292
    valine metabolic process 9.5359E-4 6 1 1 6292
    isoleucine catabolic process 9.5359E-4 6 1 1 6292
    L-serine metabolic process 1.9064E-3 6 2 1 6292
    L-serine biosynthetic process 1.9064E-3 6 2 1 6292
    leucine catabolic process 1.9064E-3 6 2 1 6292
    acetyl-CoA biosynthetic process from pyruvate 1.9064E-3 6 2 1 6292
    isoleucine metabolic process 2.8585E-3 6 3 1 6292
    acetyl-CoA biosynthetic process 3.8098E-3 6 4 1 6292
    branched chain family amino acid catabolic process 3.8098E-3 6 4 1 6292
    glycine catabolic process 5.7102E-3 6 6 1 6292
    glycine metabolic process 7.6075E-3 6 8 1 6292
    leucine metabolic process 7.6075E-3 6 8 1 6292
    serine family amino acid catabolic process 7.6075E-3 6 8 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    phosphatidylinositol binding 4.8208E-11 6 10 4 6292
    phosphoinositide binding 1.5057E-8 6 37 4 6292
    phospholipid binding 2.8093E-8 6 43 4 6292
    lipid binding 5.2331E-8 6 50 4 6292
    structural constituent of cytoskeleton 6.6487E-8 6 53 4 6292
    structural molecule activity 1.1393E-4 6 339 4 6292
    dihydrolipoyl dehydrogenase activity 9.5359E-4 6 1 1 6292
    GTPase activity 1.3526E-3 6 61 2 6292
    binding 1.819E-3 6 1294 5 6292
    oxoglutarate dehydrogenase (succinyl-transferring) activity 1.9064E-3 6 2 1 6292
    pyruvate dehydrogenase (acetyl-transferring) activity 3.8098E-3 6 4 1 6292
    pyruvate dehydrogenase activity 3.8098E-3 6 4 1 6292
    oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 4.7604E-3 6 5 1 6292
    tRNA binding 4.7604E-3 6 5 1 6292
    glycine dehydrogenase (decarboxylating) activity 5.7102E-3 6 6 1 6292
    oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 5.7102E-3 6 6 1 6292
    oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 6.6592E-3 6 7 1 6292

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