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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Mec1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 4 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

methionyl glutamyl tRNA synthetase complex 2.5411E-3 4 4 1 6292
mitochondrial matrix 4.4983E-3 4 176 2 6292
mitochondrial lumen 4.4983E-3 4 176 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

acetyl-CoA catabolic process 3.1744E-5 4 15 2 6292
tricarboxylic acid cycle 3.1744E-5 4 15 2 6292
acetyl-CoA metabolic process 5.7381E-5 4 20 2 6292
coenzyme catabolic process 5.7381E-5 4 20 2 6292
cofactor catabolic process 6.9734E-5 4 22 2 6292
carboxylic acid metabolic process 5.6477E-4 4 333 3 6292
organic acid metabolic process 5.6477E-4 4 333 3 6292
oxoacid metabolic process 5.6477E-4 4 333 3 6292
cellular ketone metabolic process 6.3273E-4 4 346 3 6292
aerobic respiration 1.014E-3 4 83 2 6292
cellular respiration 1.3833E-3 4 97 2 6292
glutamyl-tRNA aminoacylation 1.9063E-3 4 3 1 6292
coenzyme metabolic process 2.1108E-3 4 120 2 6292
citrate metabolic process 2.5411E-3 4 4 1 6292
malate metabolic process 2.5411E-3 4 4 1 6292
propionate metabolic process 3.1756E-3 4 5 1 6292
energy derivation by oxidation of organic compounds 3.2394E-3 4 149 2 6292
cofactor metabolic process 3.4575E-3 4 154 2 6292
negative regulation of DNA replication initiation 4.4437E-3 4 7 1 6292
DNA replication checkpoint 4.4437E-3 4 7 1 6292
regulation of DNA replication initiation 5.0773E-3 4 8 1 6292
generation of precursor metabolites and energy 5.5024E-3 4 195 2 6292
negative regulation of DNA replication 5.7106E-3 4 9 1 6292
cellular amino acid metabolic process 5.7261E-3 4 199 2 6292
small molecule metabolic process 6.3905E-3 4 760 3 6292
cellular amine metabolic process 7.0945E-3 4 222 2 6292
glutamate biosynthetic process 8.2408E-3 4 13 1 6292
amine metabolic process 8.465E-3 4 243 2 6292
cellular amino acid and derivative metabolic process 8.465E-3 4 243 2 6292
DNA damage response, signal transduction 8.8726E-3 4 14 1 6292
DNA damage checkpoint 8.8726E-3 4 14 1 6292
regulation of DNA replication 9.5041E-3 4 15 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

aconitate hydratase activity 1.2712E-3 4 2 1 6292
glutamate-tRNA ligase activity 1.9063E-3 4 3 1 6292
L-malate dehydrogenase activity 2.5411E-3 4 4 1 6292
malate dehydrogenase activity 3.1756E-3 4 5 1 6292

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