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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Mhp1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

microtubule cytoskeleton 2.8118E-4 2 106 2 6292
cytoskeletal part 1.0156E-3 2 201 2 6292
cytoskeleton 1.1732E-3 2 216 2 6292
mating projection base 2.224E-3 2 7 1 6292
protein phosphatase type 1 complex 2.224E-3 2 7 1 6292
mRNA cleavage and polyadenylation specificity factor complex 4.7627E-3 2 15 1 6292
protein serine/threonine phosphatase complex 5.3968E-3 2 17 1 6292
mRNA cleavage factor complex 6.3477E-3 2 20 1 6292
microtubule 9.8303E-3 2 31 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

negative regulation of cellular component organization 2.0514E-5 2 29 2 6292
negative regulation of organelle organization 2.0514E-5 2 29 2 6292
cellular protein complex disassembly 3.744E-5 2 39 2 6292
protein complex disassembly 3.744E-5 2 39 2 6292
cellular macromolecular complex disassembly 3.9411E-5 2 40 2 6292
macromolecular complex disassembly 3.9411E-5 2 40 2 6292
cellular component disassembly 4.7798E-5 2 44 2 6292
regulation of organelle organization 6.6999E-5 2 52 2 6292
regulation of cellular component organization 1.4021E-4 2 75 2 6292
histone dephosphorylation 6.3568E-4 2 2 1 6292
negative regulation of cellular process 1.5726E-3 2 250 2 6292
negative regulation of microtubule polymerization or depolymerization 1.5888E-3 2 5 1 6292
regulation of microtubule depolymerization 1.5888E-3 2 5 1 6292
negative regulation of microtubule depolymerization 1.5888E-3 2 5 1 6292
negative regulation of biological process 1.6107E-3 2 253 2 6292
cellular macromolecular complex subunit organization 1.6882E-3 2 259 2 6292
microtubule depolymerization 1.9064E-3 2 6 1 6292
negative regulation of protein complex disassembly 2.224E-3 2 7 1 6292
negative regulation of cytoskeleton organization 2.5415E-3 2 8 1 6292
cell morphogenesis during vegetative growth 2.859E-3 2 9 1 6292
termination of RNA polymerase II transcription, poly(A)-independent 2.859E-3 2 9 1 6292
protein depolymerization 3.1764E-3 2 10 1 6292
regulation of protein complex disassembly 3.1764E-3 2 10 1 6292
termination of RNA polymerase II transcription, poly(A)-coupled 3.1764E-3 2 10 1 6292
macromolecular complex subunit organization 3.2108E-3 2 357 2 6292
regulation of microtubule polymerization or depolymerization 5.3968E-3 2 17 1 6292
regulation of microtubule cytoskeleton organization 5.3968E-3 2 17 1 6292
regulation of microtubule-based process 5.3968E-3 2 17 1 6292
microtubule polymerization or depolymerization 5.7138E-3 2 18 1 6292
termination of RNA polymerase II transcription 6.0308E-3 2 19 1 6292
regulation of cytoskeleton organization 6.3477E-3 2 20 1 6292
mitotic cell cycle spindle assembly checkpoint 6.6645E-3 2 21 1 6292
negative regulation of nuclear division 6.6645E-3 2 21 1 6292
negative regulation of mitosis 6.6645E-3 2 21 1 6292
negative regulation of mitotic metaphase/anaphase transition 6.6645E-3 2 21 1 6292
spindle assembly checkpoint 6.6645E-3 2 21 1 6292
transcription termination 6.6645E-3 2 21 1 6292
negative regulation of cell cycle 6.9813E-3 2 22 1 6292
response to heat 7.6148E-3 2 24 1 6292
spindle checkpoint 7.9314E-3 2 25 1 6292
regulation of mitotic metaphase/anaphase transition 7.9314E-3 2 25 1 6292
mitotic cell cycle spindle checkpoint 7.9314E-3 2 25 1 6292
mitotic cell cycle checkpoint 8.8811E-3 2 28 1 6292
protein amino acid dephosphorylation 8.8811E-3 2 28 1 6292
regulation of nuclear division 9.1975E-3 2 29 1 6292
regulation of mitosis 9.1975E-3 2 29 1 6292
response to temperature stimulus 9.8303E-3 2 31 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

protein serine/threonine phosphatase activity 8.248E-3 2 26 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle