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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Mgt1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 16 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
AHA1
  • cytoplasm
  • protein folding
  • response to stress
  • chaperone binding
  • chaperone activator activity
  • ATPase activator activity
  • AHP1
  • cytoplasm
  • response to oxidative stress
  • response to metal ion
  • thioredoxin peroxidase activity
  • ARF1
  • cytosol
  • Golgi-associated vesicle
  • ER to Golgi vesicle-mediated transport
  • Golgi to plasma membrane transport
  • telomere maintenance
  • intra-Golgi vesicle-mediated transport
  • GTPase activity
  • GND1
  • cytoplasm
  • mitochondrion
  • response to oxidative stress
  • pentose-phosphate shunt, oxidative branch
  • phosphogluconate dehydrogenase (decarboxylating) activity
  • GPG1
  • cellular_component
  • signal transduction
  • signal transducer activity
  • HEF3
  • cytosolic ribosome
  • translational elongation
  • ATPase activity
  • translation elongation factor activity
  • HTB1
  • nuclear nucleosome
  • chromatin assembly or disassembly
  • postreplication repair
  • DNA binding
  • LHS1
  • endoplasmic reticulum lumen
  • protein transport
  • response to unfolded protein
  • unfolded protein binding
  • MGE1
  • mitochondrial matrix
  • mitochondrion
  • presequence translocase-associated import motor
  • protein import into mitochondrial matrix
  • unfolded protein binding
  • MGT1
  • nucleus
  • DNA dealkylation involved in DNA repair
  • methylated-DNA-[protein]-cysteine S-methyltransferase activity
  • RIP1
  • mitochondrion
  • mitochondrial respiratory chain complex III
  • mitochondrial electron transport, ubiquinol to cytochrome c
  • aerobic respiration
  • ubiquinol-cytochrome-c reductase activity
  • SEC27
  • COPI vesicle coat
  • ER to Golgi vesicle-mediated transport
  • retrograde vesicle-mediated transport, Golgi to ER
  • molecular_function
  • SOF1
  • nuclear outer membrane
  • nucleolus
  • small nuclear ribonucleoprotein complex
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • snoRNA binding
  • TMA19
  • cytoplasm
  • mitochondrion
  • cytosol
  • ribosome
  • response to oxidative stress
  • translation
  • molecular_function
  • UBR1
  • proteasome complex
  • protein polyubiquitination
  • protein monoubiquitination
  • ubiquitin-protein ligase activity
  • YHR033W
  • cytoplasm
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    Golgi-associated vesicle 4.4702E-3 16 40 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    response to stress 1.1206E-4 16 497 7 6292
    response to oxidative stress 6.382E-4 16 69 3 6292
    response to stimulus 1.6326E-3 16 766 7 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    phosphogluconate dehydrogenase (decarboxylating) activity 5.0798E-3 16 2 1 6292
    methylated-DNA-[protein]-cysteine S-methyltransferase activity 5.0798E-3 16 2 1 6292
    chaperone activator activity 7.6106E-3 16 3 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle