YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Glc7. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 4 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
GLC7
  • protein phosphatase type 1 complex
  • mRNA cleavage and polyadenylation specificity factor complex
  • cellular bud neck
  • spindle pole body
  • nuclear outer membrane
  • nucleolus
  • mating projection base
    		•
  • mitotic cell cycle spindle assembly checkpoint
  • cell morphogenesis during vegetative growth
  • protein amino acid dephosphorylation
  • chromosome segregation
  • cell budding
  • cellular ion homeostasis
  • meiosis
  • regulation of carbohydrate metabolic process
  • ascospore formation
  • response to heat
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • glycogen metabolic process
  • termination of RNA polymerase II transcription, poly(A)-independent
  • histone dephosphorylation
    		•
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • RNA binding
  • metal ion binding
  • hydrolase activity
    		•
    GLC8
  • nucleus
  • cytoplasm
    		•
  • glycogen biosynthetic process
  • chromosome segregation
    		•
  • enzyme activator activity
    		•
    MHP1
  • microtubule
    		•
  • cellular cell wall organization
  • negative regulation of microtubule depolymerization
    		•
  • structural constituent of cytoskeleton
    		•
    REG1
  • protein phosphatase type 1 complex
  • cytoplasm
    		•
  • negative regulation of transcription from RNA polymerase II promoter
  • regulation of carbohydrate metabolic process
  • glycogen metabolic process
  • vacuolar protein catabolic process
    		•
  • protein phosphatase type 1 regulator activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    protein phosphatase type 1 complex 6.3596E-6 4 7 2 6292
    protein serine/threonine phosphatase complex 4.1099E-5 4 17 2 6292
    microtubule cytoskeleton 1.6501E-3 4 106 2 6292
    mating projection base 4.4437E-3 4 7 1 6292
    cytoskeletal part 5.8395E-3 4 201 2 6292
    cytoskeleton 6.7241E-3 4 216 2 6292
    mRNA cleavage and polyadenylation specificity factor complex 9.5041E-3 4 15 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    glycogen metabolic process 4.7646E-7 4 32 3 6292
    energy reserve metabolic process 4.7646E-7 4 32 3 6292
    cellular glucan metabolic process 1.1839E-6 4 43 3 6292
    glucan metabolic process 1.1839E-6 4 43 3 6292
    cellular polysaccharide metabolic process 2.5132E-6 4 55 3 6292
    polysaccharide metabolic process 3.2762E-6 4 60 3 6292
    glucose metabolic process 1.9981E-5 4 109 3 6292
    hexose metabolic process 2.9463E-5 4 124 3 6292
    monosaccharide metabolic process 3.8045E-5 4 135 3 6292
    energy derivation by oxidation of organic compounds 5.1173E-5 4 149 3 6292
    generation of precursor metabolites and energy 1.1461E-4 4 195 3 6292
    negative regulation of organelle organization 1.2238E-4 4 29 2 6292
    negative regulation of cellular component organization 1.2238E-4 4 29 2 6292
    alcohol metabolic process 1.6438E-4 4 220 3 6292
    regulation of carbohydrate metabolic process 1.8962E-4 4 36 2 6292
    protein complex disassembly 2.2288E-4 4 39 2 6292
    cellular protein complex disassembly 2.2288E-4 4 39 2 6292
    cellular macromolecular complex disassembly 2.3456E-4 4 40 2 6292
    macromolecular complex disassembly 2.3456E-4 4 40 2 6292
    negative regulation of cellular process 2.4072E-4 4 250 3 6292
    negative regulation of biological process 2.4943E-4 4 253 3 6292
    cellular carbohydrate metabolic process 2.7682E-4 4 262 3 6292
    cellular component disassembly 2.8424E-4 4 44 2 6292
    carbohydrate metabolic process 3.4098E-4 4 281 3 6292
    regulation of organelle organization 3.9774E-4 4 52 2 6292
    regulation of cellular component organization 8.2831E-4 4 75 2 6292
    histone dephosphorylation 1.2712E-3 4 2 1 6292
    chromosome segregation 2.3988E-3 4 128 2 6292
    negative regulation of microtubule polymerization or depolymerization 3.1756E-3 4 5 1 6292
    regulation of microtubule depolymerization 3.1756E-3 4 5 1 6292
    negative regulation of microtubule depolymerization 3.1756E-3 4 5 1 6292
    microtubule depolymerization 3.8098E-3 4 6 1 6292
    negative regulation of protein complex disassembly 4.4437E-3 4 7 1 6292
    negative regulation of cytoskeleton organization 5.0773E-3 4 8 1 6292
    termination of RNA polymerase II transcription, poly(A)-independent 5.7106E-3 4 9 1 6292
    cell morphogenesis during vegetative growth 5.7106E-3 4 9 1 6292
    regulation of protein complex disassembly 6.3436E-3 4 10 1 6292
    termination of RNA polymerase II transcription, poly(A)-coupled 6.3436E-3 4 10 1 6292
    protein depolymerization 6.3436E-3 4 10 1 6292
    small molecule metabolic process 6.3905E-3 4 760 3 6292
    regulation of cellular process 7.309E-3 4 796 3 6292
    regulation of biological process 8.0789E-3 4 824 3 6292
    vacuolar protein catabolic process 8.8726E-3 4 14 1 6292
    glycogen biosynthetic process 9.5041E-3 4 15 1 6292
    cellular macromolecular complex subunit organization 9.5855E-3 4 259 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    enzyme regulator activity 6.1862E-3 4 207 2 6292
    protein phosphatase type 1 regulator activity 7.6087E-3 4 12 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle