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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 5 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication factor C complex 5.6308E-15 5 11 5 6292
replication fork 1.0368E-11 5 42 5 6292
chromosomal part 7.2786E-8 5 237 5 6292
chromosome 1.512E-7 5 274 5 6292
intracellular non-membrane-bounded organelle 8.1528E-5 5 959 5 6292
non-membrane-bounded organelle 8.1528E-5 5 959 5 6292
protein complex 1.913E-4 5 1137 5 6292
macromolecular complex 1.1794E-3 5 1635 5 6292
organelle part 6.2578E-3 5 2282 5 6292
intracellular organelle part 6.2578E-3 5 2282 5 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

leading strand elongation 1.0446E-10 5 15 4 6292
mismatch repair 1.3411E-9 5 27 4 6292
DNA strand elongation 2.4031E-9 5 31 4 6292
DNA strand elongation involved in DNA replication 2.4031E-9 5 31 4 6292
DNA replication 2.6335E-9 5 123 5 6292
DNA repair 2.5145E-8 5 192 5 6292
response to DNA damage stimulus 7.125E-8 5 236 5 6292
DNA-dependent DNA replication 1.3271E-7 5 82 4 6292
cellular response to stress 2.0123E-7 5 290 5 6292
cellular response to stimulus 7.7346E-7 5 379 5 6292
sister chromatid cohesion 1.187E-6 5 32 3 6292
response to stress 3.0183E-6 5 497 5 6292
DNA metabolic process 6.8404E-6 5 585 5 6292
response to stimulus 2.6437E-5 5 766 5 6292
chromosome segregation 7.9834E-5 5 128 3 6292
cellular macromolecule biosynthetic process 2.3732E-4 5 1187 5 6292
macromolecule biosynthetic process 2.3933E-4 5 1189 5 6292
chromosome organization 2.787E-4 5 555 4 6292
nucleic acid metabolic process 5.7208E-4 5 1415 5 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 9.5045E-4 5 1566 5 6292
cellular biosynthetic process 9.5349E-4 5 1567 5 6292
biosynthetic process 1.065E-3 5 1602 5 6292
cellular nitrogen compound metabolic process 1.7545E-3 5 1770 5 6292
nitrogen compound metabolic process 1.8612E-3 5 1791 5 6292
cell cycle process 4.1678E-3 5 490 3 6292
organelle organization 4.3919E-3 5 1127 4 6292
cell cycle 5.0831E-3 5 525 3 6292
cellular macromolecule metabolic process 6.2991E-3 5 2285 5 6292
regulation of transposition, DNA-mediated 6.3431E-3 5 8 1 6292
negative regulation of transposition, DNA-mediated 6.3431E-3 5 8 1 6292
transposition, DNA-mediated 6.3431E-3 5 8 1 6292
negative regulation of transposition 7.1338E-3 5 9 1 6292
regulation of transposition 7.1338E-3 5 9 1 6292
macromolecule metabolic process 7.2329E-3 5 2349 5 6292
negative regulation of DNA recombination 9.5026E-3 5 12 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

protein-DNA loading ATPase activity 2.6813E-12 5 7 4 6292
DNA clamp loader activity 2.6813E-12 5 7 4 6292
DNA-dependent ATPase activity 2.5968E-8 5 55 4 6292
ATPase activity, coupled 1.4834E-6 5 149 4 6292
ATPase activity 5.9889E-6 5 211 4 6292
DNA binding 1.2966E-5 5 256 4 6292
nucleoside-triphosphatase activity 3.5215E-5 5 329 4 6292
hydrolase activity, acting on acid anhydrides 4.658E-5 5 353 4 6292
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4.658E-5 5 353 4 6292
pyrophosphatase activity 4.658E-5 5 353 4 6292
nucleic acid binding 5.7016E-4 5 666 4 6292
hydrolase activity 1.9328E-3 5 911 4 6292
binding 7.4489E-3 5 1294 4 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle