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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 4 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

transcription factor TFIID complex 3.1744E-5 4 15 2 6292
DNA-directed RNA polymerase II, holoenzyme 4.6154E-4 4 56 2 6292
transcription factor complex 7.4238E-4 4 71 2 6292
nucleoplasm part 8.6014E-3 4 245 2 6292
nucleoplasm 9.9491E-3 4 264 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

transcription, DNA-dependent 4.0396E-5 4 503 4 6292
RNA biosynthetic process 4.2031E-5 4 508 4 6292
transcription 5.8652E-5 4 552 4 6292
RNA metabolic process 5.2568E-4 4 954 4 6292
transcription from RNA polymerase II promoter 5.749E-4 4 335 3 6292
regulation of transcription, DNA-dependent 7.0003E-4 4 358 3 6292
regulation of RNA metabolic process 7.294E-4 4 363 3 6292
regulation of transcription 8.6159E-4 4 384 3 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.084E-3 4 415 3 6292
regulation of nitrogen compound metabolic process 1.0917E-3 4 416 3 6292
cellular macromolecule biosynthetic process 1.2614E-3 4 1187 4 6292
macromolecule biosynthetic process 1.27E-3 4 1189 4 6292
regulation of gene expression 1.3321E-3 4 445 3 6292
regulation of macromolecule biosynthetic process 1.4316E-3 4 456 3 6292
regulation of cellular biosynthetic process 1.5848E-3 4 472 3 6292
regulation of biosynthetic process 1.5947E-3 4 473 3 6292
gene expression 1.7224E-3 4 1283 4 6292
regulation of macromolecule metabolic process 1.7483E-3 4 488 3 6292
regulation of primary metabolic process 2.0368E-3 4 514 3 6292
regulation of cellular metabolic process 2.3038E-3 4 536 3 6292
regulation of metabolic process 2.4454E-3 4 547 3 6292
nucleic acid metabolic process 2.5494E-3 4 1415 4 6292
negative regulation of transcription, DNA-dependent 3.5916E-3 4 157 2 6292
negative regulation of RNA metabolic process 3.6369E-3 4 158 2 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.8261E-3 4 1566 4 6292
cellular biosynthetic process 3.8359E-3 4 1567 4 6292
negative regulation of gene expression 3.9142E-3 4 164 2 6292
negative regulation of transcription 3.9142E-3 4 164 2 6292
biosynthetic process 4.1907E-3 4 1602 4 6292
negative regulation of macromolecule biosynthetic process 4.4481E-3 4 175 2 6292
negative regulation of nitrogen compound metabolic process 4.7016E-3 4 180 2 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.7016E-3 4 180 2 6292
negative regulation of biosynthetic process 5.1748E-3 4 189 2 6292
negative regulation of cellular biosynthetic process 5.1748E-3 4 189 2 6292
negative regulation of macromolecule metabolic process 5.3374E-3 4 192 2 6292
cellular nitrogen compound metabolic process 6.2471E-3 4 1770 4 6292
negative regulation of cellular metabolic process 6.3039E-3 4 209 2 6292
negative regulation of metabolic process 6.3631E-3 4 210 2 6292
nitrogen compound metabolic process 6.5492E-3 4 1791 4 6292
regulation of cellular process 7.309E-3 4 796 3 6292
regulation of transcription from RNA polymerase II promoter 7.4744E-3 4 228 2 6292
regulation of biological process 8.0789E-3 4 824 3 6292
regulation of transcription involved in G1 phase of mitotic cell cycle 8.8726E-3 4 14 1 6292
negative regulation of cellular process 8.9471E-3 4 250 2 6292
negative regulation of biological process 9.1576E-3 4 253 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

transcription regulator activity 5.9551E-4 4 339 3 6292
RNA polymerase II transcription factor activity 2.4736E-3 4 130 2 6292
DNA bending activity 8.2408E-3 4 13 1 6292
specific transcriptional repressor activity 9.5041E-3 4 15 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle