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View Protein Complex Details

Complex Overview

From Publication: Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes: MIPS hand-curated complex set. MIPS complex ID: 445.10
Complex Size: 5 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CDC34
  • nucleus
  • cytoplasm
  • SCF ubiquitin ligase complex
  • G2/M transition of mitotic cell cycle
  • protein polyubiquitination
  • G1/S transition of mitotic cell cycle
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • protein ubiquitination during ubiquitin-dependent protein catabolic process
  • protein autoubiquitination
  • ubiquitin-protein ligase activity
  • CDC4
  • nucleus
  • nuclear matrix
  • SCF ubiquitin ligase complex
  • nuclear SCF ubiquitin ligase complex
  • G2/M transition of mitotic cell cycle
  • G1/S transition of mitotic cell cycle
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • meiosis
  • protein ubiquitination during ubiquitin-dependent protein catabolic process
  • ubiquitin-protein ligase activity
  • CDC53
  • SCF ubiquitin ligase complex
  • G2/M transition of mitotic cell cycle
  • G1/S transition of mitotic cell cycle
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • protein ubiquitination during ubiquitin-dependent protein catabolic process
  • DNA replication origin binding
  • ubiquitin-protein ligase activity
  • protein binding, bridging
  • SGT1
  • ubiquitin ligase complex
  • protein complex assembly
  • kinetochore assembly
  • cAMP-mediated signaling
  • protein ubiquitination
  • chaperone binding
  • SKP1
  • RAVE complex
  • nucleus
  • cytoplasm
  • CBF3 complex
  • SCF ubiquitin ligase complex
  • kinetochore
  • G2/M transition of mitotic cell cycle
  • protein complex assembly
  • regulation of exit from mitosis
  • G1/S transition of mitotic cell cycle
  • cytokinesis
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • regulation of protein complex assembly
  • protein neddylation
  • kinetochore assembly
  • vacuolar acidification
  • protein ubiquitination during ubiquitin-dependent protein catabolic process
  • DNA replication origin binding
  • ubiquitin-protein ligase activity
  • protein binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ubiquitin ligase complex 1.1732E-11 5 43 5 6292
    SCF ubiquitin ligase complex 2.5268E-11 5 11 4 6292
    cullin-RING ubiquitin ligase complex 7.6616E-11 5 14 4 6292
    protein complex 1.913E-4 5 1137 5 6292
    macromolecular complex 1.1794E-3 5 1635 5 6292
    nuclear SCF ubiquitin ligase complex 1.5888E-3 5 2 1 6292
    nuclear matrix 1.5888E-3 5 2 1 6292
    nuclear periphery 1.5888E-3 5 2 1 6292
    RAVE complex 2.3825E-3 5 3 1 6292
    CBF3 complex 3.1756E-3 5 4 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 2.6813E-12 5 7 4 6292
    protein ubiquitination during ubiquitin-dependent protein catabolic process 2.5268E-11 5 11 4 6292
    protein ubiquitination 1.0067E-10 5 65 5 6292
    protein modification by small protein conjugation 4.2446E-10 5 86 5 6292
    protein modification by small protein conjugation or removal 1.7892E-9 5 114 5 6292
    G2/M transition of mitotic cell cycle 1.8144E-9 5 29 4 6292
    G1/S transition of mitotic cell cycle 1.7546E-8 5 50 4 6292
    proteasomal protein catabolic process 6.5705E-8 5 69 4 6292
    proteasomal ubiquitin-dependent protein catabolic process 6.5705E-8 5 69 4 6292
    interphase of mitotic cell cycle 2.6239E-7 5 97 4 6292
    interphase 2.6239E-7 5 97 4 6292
    post-translational protein modification 5.7263E-7 5 357 5 6292
    centromere complex assembly 1.5153E-6 5 3 2 6292
    kinetochore assembly 1.5153E-6 5 3 2 6292
    kinetochore organization 1.5153E-6 5 3 2 6292
    modification-dependent protein catabolic process 1.7841E-6 5 156 4 6292
    ubiquitin-dependent protein catabolic process 1.7841E-6 5 156 4 6292
    proteolysis involved in cellular protein catabolic process 1.926E-6 5 159 4 6292
    modification-dependent macromolecule catabolic process 2.1811E-6 5 164 4 6292
    cellular protein catabolic process 2.5795E-6 5 171 4 6292
    protein modification process 3.0798E-6 5 499 5 6292
    proteolysis 3.7725E-6 5 188 4 6292
    protein catabolic process 3.8535E-6 5 189 4 6292
    macromolecule modification 5.9519E-6 5 569 5 6292
    mitotic cell cycle 1.2765E-5 5 255 4 6292
    cellular macromolecule catabolic process 1.4882E-5 5 265 4 6292
    macromolecule catabolic process 2.2511E-5 5 294 4 6292
    cell cycle phase 5.9837E-5 5 376 4 6292
    cellular catabolic process 8.8471E-5 5 415 4 6292
    cellular protein metabolic process 1.4379E-4 5 1074 5 6292
    cell cycle process 1.7059E-4 5 490 4 6292
    catabolic process 1.7899E-4 5 496 4 6292
    protein metabolic process 1.9046E-4 5 1136 5 6292
    cell cycle 2.2393E-4 5 525 4 6292
    protein-DNA complex assembly 3.7002E-4 5 39 2 6292
    cellular protein complex assembly 7.1116E-4 5 54 2 6292
    protein autoubiquitination 7.9466E-4 5 1 1 6292
    organelle assembly 1.1603E-3 5 69 2 6292
    cyclic-nucleotide-mediated signaling 5.552E-3 5 7 1 6292
    protein neddylation 5.552E-3 5 7 1 6292
    cAMP-mediated signaling 5.552E-3 5 7 1 6292
    protein complex biogenesis 5.7423E-3 5 155 2 6292
    protein complex assembly 5.7423E-3 5 155 2 6292
    cellular macromolecule metabolic process 6.2991E-3 5 2285 5 6292
    macromolecule metabolic process 7.2329E-3 5 2349 5 6292
    cellular macromolecular complex assembly 7.856E-3 5 182 2 6292
    regulation of protein complex assembly 8.7135E-3 5 11 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ubiquitin-protein ligase activity 3.0068E-8 5 57 4 6292
    small conjugating protein ligase activity 4.2436E-8 5 62 4 6292
    acid-amino acid ligase activity 7.3829E-8 5 71 4 6292
    ligase activity, forming carbon-nitrogen bonds 2.3103E-7 5 94 4 6292
    ligase activity 1.5239E-6 5 150 4 6292
    DNA replication origin binding 3.9273E-5 5 13 2 6292
    sequence-specific DNA binding 6.0956E-4 5 50 2 6292
    protein binding 7.8822E-3 5 612 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle