YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 14 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
CFT1
  • mRNA cleavage and polyadenylation specificity factor complex
  • mitochondrion
  • mRNA cleavage factor complex
    		•
  • termination of RNA polymerase II transcription
  • mRNA polyadenylation
  • mRNA cleavage
    		•
  • RNA binding
    		•
    CFT2
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA cleavage factor complex
    		•
  • mRNA polyadenylation
  • mRNA cleavage
    		•
  • RNA binding
    		•
    FIP1
  • mRNA cleavage and polyadenylation specificity factor complex
    		•
  • mRNA polyadenylation
  • mRNA cleavage
    		•
  • RNA binding
  • protein binding
    		•
    GLC7
  • protein phosphatase type 1 complex
  • mRNA cleavage and polyadenylation specificity factor complex
  • cellular bud neck
  • spindle pole body
  • nuclear outer membrane
  • nucleolus
  • mating projection base
    		•
  • mitotic cell cycle spindle assembly checkpoint
  • cell morphogenesis during vegetative growth
  • protein amino acid dephosphorylation
  • chromosome segregation
  • cell budding
  • cellular ion homeostasis
  • meiosis
  • regulation of carbohydrate metabolic process
  • ascospore formation
  • response to heat
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • glycogen metabolic process
  • termination of RNA polymerase II transcription, poly(A)-independent
  • histone dephosphorylation
    		•
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • RNA binding
  • metal ion binding
  • hydrolase activity
    		•
    MPE1
  • mRNA cleavage and polyadenylation specificity factor complex
    		•
  • mRNA polyadenylation
  • mRNA cleavage
    		•
  • RNA binding
    		•
    PAP1
  • mRNA cleavage and polyadenylation specificity factor complex
  • nucleoplasm
    		•
  • mRNA export from nucleus
  • mRNA polyadenylation
    		•
  • polynucleotide adenylyltransferase activity
    		•
    PFS2
  • mRNA cleavage and polyadenylation specificity factor complex
    		•
  • mRNA polyadenylation
  • mRNA cleavage
    		•
  • RNA binding
    		•
    PTA1
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA cleavage factor complex
    		•
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • tRNA processing
  • termination of RNA polymerase II transcription, poly(A)-independent
  • mRNA polyadenylation
  • mRNA cleavage
    		•
  • RNA binding
    		•
    PTI1
  • nucleus
  • mRNA cleavage and polyadenylation specificity factor complex
    		•
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • termination of RNA polymerase II transcription, poly(A)-independent
  • mRNA polyadenylation
  • mRNA cleavage
  • snoRNA 3'-end processing
    		•
  • RNA binding
    		•
    REF2
  • nucleus
  • mRNA cleavage and polyadenylation specificity factor complex
    		•
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • termination of RNA polymerase II transcription, poly(A)-independent
  • telomere maintenance
  • mRNA processing
  • snoRNA 3'-end processing
    		•
  • DNA binding
  • RNA binding
    		•
    SSU72
  • nucleus
  • mRNA cleavage and polyadenylation specificity factor complex
  • nuclear outer membrane
    		•
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • termination of RNA polymerase II transcription, poly(A)-independent
  • snoRNA transcription
  • termination of RNA polymerase II transcription
  • transcription initiation from RNA polymerase II promoter
    		•
  • phosphoprotein phosphatase activity
  • RNA binding
  • protein tyrosine phosphatase activity
  • phosphoric ester hydrolase activity
    		•
    SWD2
  • Set1C/COMPASS complex
  • mRNA cleavage and polyadenylation specificity factor complex
    		•
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • termination of RNA polymerase II transcription, poly(A)-independent
  • histone methylation
  • telomere maintenance
  • mRNA 3'-end processing
  • snoRNA 3'-end processing
    		•
  • histone methyltransferase activity (H3-K4 specific)
    		•
    YSH1
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA cleavage factor complex
    		•
  • mRNA polyadenylation
  • mRNA cleavage
    		•
  • RNA binding
  • endoribonuclease activity
    		•
    YTH1
  • mRNA cleavage and polyadenylation specificity factor complex
    		•
  • mRNA polyadenylation
  • mRNA cleavage
    		•
  • RNA binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    mRNA cleavage and polyadenylation specificity factor complex 8.7045E-42 14 15 14 6292
    mRNA cleavage factor complex 2.2492E-38 14 20 14 6292
    nucleoplasm part 1.28E-20 14 245 14 6292
    nucleoplasm 3.7444E-20 14 264 14 6292
    nuclear lumen 8.3271E-17 14 453 14 6292
    organelle lumen 1.7241E-14 14 660 14 6292
    intracellular organelle lumen 1.7241E-14 14 660 14 6292
    membrane-enclosed lumen 3.9609E-14 14 700 14 6292
    nuclear part 2.4173E-11 14 1103 14 6292
    protein complex 3.7067E-11 14 1137 14 6292
    macromolecular complex 6.1412E-9 14 1635 14 6292
    nucleus 1.3856E-7 14 2041 14 6292
    intracellular organelle part 6.6422E-7 14 2282 14 6292
    organelle part 6.6422E-7 14 2282 14 6292
    membrane-bounded organelle 7.6409E-4 14 3771 14 6292
    intracellular membrane-bounded organelle 7.6409E-4 14 3771 14 6292
    intracellular organelle 2.2276E-3 14 4070 14 6292
    organelle 2.2353E-3 14 4071 14 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    RNA 3'-end processing 1.254E-25 14 42 12 6292
    mRNA 3'-end processing 2.0105E-24 14 31 11 6292
    mRNA polyadenylation 3.4572E-24 14 19 10 6292
    RNA polyadenylation 1.9798E-22 14 26 10 6292
    mRNA cleavage 9.5476E-20 14 25 9 6292
    mRNA processing 3.0805E-18 14 156 12 6292
    nucleic acid phosphodiester bond hydrolysis 5.0716E-17 14 46 9 6292
    mRNA metabolic process 1.4308E-16 14 213 12 6292
    termination of RNA polymerase II transcription 2.2139E-15 14 19 7 6292
    termination of RNA polymerase II transcription, poly(A)-independent 2.9245E-15 14 9 6 6292
    transcription termination 5.0989E-15 14 21 7 6292
    termination of RNA polymerase II transcription, poly(A)-coupled 7.3032E-15 14 10 6 6292
    RNA processing 1.6257E-13 14 380 12 6292
    protein complex disassembly 6.6269E-13 14 39 7 6292
    cellular protein complex disassembly 6.6269E-13 14 39 7 6292
    cellular macromolecular complex disassembly 8.0248E-13 14 40 7 6292
    macromolecular complex disassembly 8.0248E-13 14 40 7 6292
    cellular component disassembly 1.643E-12 14 44 7 6292
    RNA metabolic process 3.1282E-12 14 954 14 6292
    gene expression 2.03E-10 14 1283 14 6292
    nucleic acid metabolic process 8.0503E-10 14 1415 14 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.3498E-9 14 1566 14 6292
    cellular nitrogen compound metabolic process 1.8728E-8 14 1770 14 6292
    nitrogen compound metabolic process 2.2103E-8 14 1791 14 6292
    snoRNA metabolic process 4.6119E-8 14 18 4 6292
    snoRNA 3'-end processing 8.7489E-8 14 5 3 6292
    snoRNA processing 3.0541E-7 14 7 3 6292
    cellular macromolecular complex subunit organization 4.9504E-7 14 259 7 6292
    cellular macromolecule metabolic process 6.7658E-7 14 2285 14 6292
    macromolecule metabolic process 9.9712E-7 14 2349 14 6292
    ncRNA 3'-end processing 1.9071E-6 14 12 3 6292
    transcription from RNA polymerase II promoter 2.8286E-6 14 335 7 6292
    macromolecular complex subunit organization 4.3342E-6 14 357 7 6292
    primary metabolic process 1.8826E-5 14 2896 14 6292
    cellular metabolic process 3.6009E-5 14 3033 14 6292
    transcription, DNA-dependent 4.1825E-5 14 503 7 6292
    RNA biosynthetic process 4.461E-5 14 508 7 6292
    metabolic process 6.3176E-5 14 3157 14 6292
    transcription 7.6467E-5 14 552 7 6292
    ncRNA metabolic process 1.6164E-4 14 257 5 6292
    ncRNA processing 1.0131E-3 14 215 4 6292
    snoRNA transcription 2.225E-3 14 1 1 6292
    histone dephosphorylation 4.4455E-3 14 2 1 6292
    cellular process 7.2188E-3 14 4426 14 6292
    cellular macromolecule biosynthetic process 8.2989E-3 14 1187 7 6292
    macromolecule biosynthetic process 8.3784E-3 14 1189 7 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    RNA binding 1.0682E-13 14 367 12 6292
    nucleic acid binding 1.3452E-10 14 666 12 6292
    binding 3.2953E-7 14 1294 12 6292
    phosphoprotein phosphatase activity 3.941E-3 14 43 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle