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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 8 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
FUN12
  • mitochondrion
  • translational initiation
  • translation initiation factor activity
  • GTPase activity
  • MAK5
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • ribosomal large subunit assembly
  • ATP-dependent RNA helicase activity
  • PRP43
  • mitochondrion
  • spliceosomal complex
  • nuclear outer membrane
  • maturation of SSU-rRNA
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • rRNA processing
  • processing of 27S pre-rRNA
  • ATP-dependent RNA helicase activity
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS7A
  • small nucleolar ribonucleoprotein complex
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribonucleoprotein complex 7.018E-6 8 514 6 6292
    90S preribosome 1.9058E-4 8 17 2 6292
    cytosolic ribosome 2.1208E-4 8 101 3 6292
    cytosolic part 3.71E-4 8 122 3 6292
    preribosome 7.7767E-4 8 34 2 6292
    cytosolic small ribosomal subunit 9.7204E-4 8 38 2 6292
    ribosomal subunit 1.2169E-3 8 183 3 6292
    non-membrane-bounded organelle 3.0487E-3 8 959 5 6292
    intracellular non-membrane-bounded organelle 3.0487E-3 8 959 5 6292
    small nucleolar ribonucleoprotein complex 3.4584E-3 8 72 2 6292
    small ribosomal subunit 3.5536E-3 8 73 2 6292
    cytosol 4.3023E-3 8 284 3 6292
    ribosome 4.565E-3 8 290 3 6292
    nuclear outer membrane 4.9014E-3 8 86 2 6292
    macromolecular complex 5.1894E-3 8 1635 6 6292
    nuclear membrane 6.2001E-3 8 97 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    gene expression 2.9372E-6 8 1283 8 6292
    rRNA processing 1.0741E-5 8 128 4 6292
    rRNA metabolic process 1.4075E-5 8 137 4 6292
    translation 3.5782E-5 8 376 5 6292
    maturation of SSU-rRNA 4.2427E-5 8 59 3 6292
    ncRNA processing 8.3316E-5 8 215 4 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.0958E-4 8 13 2 6292
    ncRNA metabolic process 1.6718E-4 8 257 4 6292
    cellular macromolecule metabolic process 3.0018E-4 8 2285 8 6292
    macromolecule metabolic process 3.7455E-4 8 2349 8 6292
    ribosome biogenesis 5.2727E-4 8 346 4 6292
    ribonucleoprotein complex biogenesis 7.1014E-4 8 374 4 6292
    RNA processing 7.546E-4 8 380 4 6292
    primary metabolic process 2.0036E-3 8 2896 8 6292
    regulation of translation 2.1802E-3 8 57 2 6292
    posttranscriptional regulation of gene expression 2.4935E-3 8 61 2 6292
    ribosomal large subunit biogenesis 2.8269E-3 8 65 2 6292
    cellular metabolic process 2.9013E-3 8 3033 8 6292
    regulation of cellular protein metabolic process 3.0901E-3 8 68 2 6292
    regulation of protein metabolic process 3.6499E-3 8 74 2 6292
    metabolic process 3.9991E-3 8 3157 8 6292
    cellular protein metabolic process 5.103E-3 8 1074 5 6292
    protein metabolic process 6.5695E-3 8 1136 5 6292
    cellular component biogenesis 7.1352E-3 8 694 4 6292
    cellular macromolecule biosynthetic process 7.9943E-3 8 1187 5 6292
    macromolecule biosynthetic process 8.0545E-3 8 1189 5 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 7.8854E-5 8 212 4 6292
    structural molecule activity 4.8751E-4 8 339 4 6292
    ATP-dependent RNA helicase activity 5.26E-4 8 28 2 6292
    RNA-dependent ATPase activity 5.646E-4 8 29 2 6292
    RNA helicase activity 1.1875E-3 8 42 2 6292
    ATP-dependent helicase activity 1.5498E-3 8 48 2 6292
    purine NTP-dependent helicase activity 1.5498E-3 8 48 2 6292
    helicase activity 4.5722E-3 8 83 2 6292
    nucleic acid binding 6.1432E-3 8 666 4 6292
    nucleoside-triphosphatase activity 6.5162E-3 8 329 3 6292
    hydrolase activity, acting on acid anhydrides 7.936E-3 8 353 3 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 7.936E-3 8 353 3 6292
    pyrophosphatase activity 7.936E-3 8 353 3 6292
    RNA binding 8.8446E-3 8 367 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle