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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 16 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
    		•
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
    		•
  • molecular_function
    		•
    ENP1
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • preribosome, small subunit precursor
    		•
  • ribosome biogenesis
  • rRNA processing
    		•
  • snoRNA binding
    		•
    IMP3
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
    		•
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
    		•
  • snoRNA binding
    		•
    MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
    		•
  • maturation of SSU-rRNA
  • ribosome biogenesis
    		•
  • molecular_function
    		•
    NAN1
  • RENT complex
  • small nucleolar ribonucleoprotein complex
    		•
  • maturation of SSU-rRNA
  • ribosome biogenesis
    		•
  • snoRNA binding
    		•
    NOC4
  • nucleus
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
    		•
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
    		•
  • molecular_function
    		•
    NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
    		•
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
    		•
  • methyltransferase activity
    		•
    PNO1
  • nucleus
  • nuclear outer membrane
  • nucleolus
    		•
  • protein complex assembly
  • ribosome biogenesis
  • rRNA processing
    		•
  • unfolded protein binding
    		•
    UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
    		•
  • maturation of SSU-rRNA
  • ribosome biogenesis
    		•
  • snoRNA binding
    		•
    UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
    		•
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
    		•
  • snoRNA binding
    		•
    UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
    		•
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
    		•
  • snoRNA binding
    		•
    UTP30
  • nucleus
  • nuclear outer membrane
  • nucleolus
    		•
  • ribosome biogenesis
    		•
  • molecular_function
    		•
    UTP4
  • small nucleolar ribonucleoprotein complex
    		•
  • maturation of SSU-rRNA
  • ribosome biogenesis
    		•
  • snoRNA binding
    		•
    UTP6
  • small nucleolar ribonucleoprotein complex
    		•
  • maturation of SSU-rRNA
  • ribosome biogenesis
    		•
  • snoRNA binding
    		•
    UTP7
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
    		•
  • ribosome biogenesis
  • rRNA processing
    		•
  • snoRNA binding
    		•
    UTP8
  • small nucleolar ribonucleoprotein complex
    		•
  • maturation of SSU-rRNA
  • ribosome biogenesis
    		•
  • snoRNA binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    small nucleolar ribonucleoprotein complex 1.0066E-23 16 72 13 6292
    nuclear outer membrane 6.6557E-18 16 86 11 6292
    nuclear membrane 2.6842E-17 16 97 11 6292
    outer membrane 2.6396E-14 16 178 11 6292
    organelle outer membrane 2.6396E-14 16 178 11 6292
    ribonucleoprotein complex 5.1434E-14 16 514 14 6292
    nuclear envelope 9.1661E-14 16 199 11 6292
    nuclear membrane-endoplasmic reticulum network 5.0356E-13 16 232 11 6292
    nucleolus 9.7865E-12 16 211 10 6292
    endomembrane system 1.8595E-10 16 398 11 6292
    envelope 2.419E-9 16 505 11 6292
    organelle envelope 2.419E-9 16 505 11 6292
    nuclear lumen 1.8358E-8 16 453 10 6292
    membrane part 4.3059E-8 16 662 11 6292
    organelle membrane 6.8687E-8 16 692 11 6292
    macromolecular complex 4.2472E-7 16 1635 14 6292
    organelle lumen 6.7223E-7 16 660 10 6292
    intracellular organelle lumen 6.7223E-7 16 660 10 6292
    nuclear part 7.2588E-7 16 1103 12 6292
    membrane-enclosed lumen 1.1699E-6 16 700 10 6292
    preribosome 1.2357E-6 16 34 4 6292
    membrane 1.9435E-5 16 1198 11 6292
    non-membrane-bounded organelle 2.1518E-5 16 959 10 6292
    intracellular non-membrane-bounded organelle 2.1518E-5 16 959 10 6292
    small-subunit processome 9.041E-5 16 6 2 6292
    preribosome, small subunit precursor 9.041E-5 16 6 2 6292
    nucleus 5.8981E-4 16 2041 12 6292
    intracellular organelle part 1.8408E-3 16 2282 12 6292
    organelle part 1.8408E-3 16 2282 12 6292
    Noc4p-Nop14p complex 5.0798E-3 16 2 1 6292
    nucleolar part 5.6318E-3 16 45 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    ribosome biogenesis 5.0115E-21 16 346 16 6292
    ribonucleoprotein complex biogenesis 1.7877E-20 16 374 16 6292
    rRNA processing 2.9308E-20 16 128 13 6292
    rRNA metabolic process 7.3694E-20 16 137 13 6292
    maturation of SSU-rRNA 1.8118E-17 16 59 10 6292
    ncRNA processing 3.096E-17 16 215 13 6292
    ncRNA metabolic process 3.2853E-16 16 257 13 6292
    cellular component biogenesis 4.1092E-16 16 694 16 6292
    RNA processing 5.5421E-14 16 380 13 6292
    RNA metabolic process 7.4593E-9 16 954 13 6292
    gene expression 3.0134E-7 16 1283 13 6292
    nucleic acid metabolic process 1.0065E-6 16 1415 13 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.4714E-6 16 1566 13 6292
    cellular nitrogen compound metabolic process 1.5225E-5 16 1770 13 6292
    nitrogen compound metabolic process 1.7535E-5 16 1791 13 6292
    cellular macromolecule metabolic process 3.0772E-4 16 2285 13 6292
    macromolecule metabolic process 4.2263E-4 16 2349 13 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.6527E-4 16 13 2 6292
    rRNA modification 9.059E-4 16 18 2 6292
    ribosomal small subunit biogenesis 1.9016E-3 16 26 2 6292
    cellular process 3.565E-3 16 4426 16 6292
    primary metabolic process 4.3709E-3 16 2896 13 6292
    cellular metabolic process 7.176E-3 16 3033 13 6292
    ncRNA 5'-end processing 7.6106E-3 16 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 7.6106E-3 16 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 7.6106E-3 16 3 1 6292
    rRNA 5'-end processing 7.6106E-3 16 3 1 6292
    RNA 5'-end processing 7.6106E-3 16 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    snoRNA binding 1.3107E-20 16 31 10 6292
    RNA binding 2.3636E-9 16 367 10 6292
    nucleic acid binding 7.3215E-7 16 666 10 6292
    binding 4.183E-5 16 1294 11 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle