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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.084] [SVM Score: 0.503307841628]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

cytoplasmic microtubule 4.5979E-6 2 14 2 6292
microtubule 2.3495E-5 2 31 2 6292
microtubule cytoskeleton 2.8118E-4 2 106 2 6292
cytoskeletal part 1.0156E-3 2 201 2 6292
cytoskeleton 1.1732E-3 2 216 2 6292
kinesin complex 2.224E-3 2 7 1 6292
microtubule associated complex 5.7138E-3 2 18 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

negative regulation of microtubule polymerization or depolymerization 5.0527E-7 2 5 2 6292
regulation of microtubule depolymerization 5.0527E-7 2 5 2 6292
negative regulation of microtubule depolymerization 5.0527E-7 2 5 2 6292
microtubule depolymerization 7.579E-7 2 6 2 6292
negative regulation of protein complex disassembly 1.0611E-6 2 7 2 6292
negative regulation of cytoskeleton organization 1.4147E-6 2 8 2 6292
protein depolymerization 2.2737E-6 2 10 2 6292
regulation of protein complex disassembly 2.2737E-6 2 10 2 6292
microtubule-based movement 6.0632E-6 2 16 2 6292
microtubule-based transport 6.0632E-6 2 16 2 6292
nuclear migration along microtubule 6.0632E-6 2 16 2 6292
regulation of microtubule polymerization or depolymerization 6.8716E-6 2 17 2 6292
regulation of microtubule-based process 6.8716E-6 2 17 2 6292
regulation of microtubule cytoskeleton organization 6.8716E-6 2 17 2 6292
cytoskeleton-dependent intracellular transport 7.7306E-6 2 18 2 6292
microtubule polymerization or depolymerization 7.7306E-6 2 18 2 6292
nuclear migration 9.6001E-6 2 20 2 6292
nucleus localization 9.6001E-6 2 20 2 6292
regulation of cytoskeleton organization 9.6001E-6 2 20 2 6292
establishment of nucleus localization 9.6001E-6 2 20 2 6292
negative regulation of cellular component organization 2.0514E-5 2 29 2 6292
negative regulation of organelle organization 2.0514E-5 2 29 2 6292
cellular protein complex disassembly 3.744E-5 2 39 2 6292
protein complex disassembly 3.744E-5 2 39 2 6292
cellular macromolecular complex disassembly 3.9411E-5 2 40 2 6292
macromolecular complex disassembly 3.9411E-5 2 40 2 6292
cellular component disassembly 4.7798E-5 2 44 2 6292
regulation of organelle organization 6.6999E-5 2 52 2 6292
establishment of organelle localization 7.5032E-5 2 55 2 6292
regulation of cellular component organization 1.4021E-4 2 75 2 6292
organelle localization 1.8038E-4 2 85 2 6292
microtubule cytoskeleton organization 2.3525E-4 2 97 2 6292
mitosis 2.7062E-4 2 104 2 6292
nuclear division 2.8118E-4 2 106 2 6292
microtubule-based process 3.0847E-4 2 111 2 6292
organelle fission 3.1973E-4 2 113 2 6292
M phase of mitotic cell cycle 4.1068E-4 2 128 2 6292
cytoskeleton organization 1.3422E-3 2 231 2 6292
negative regulation of cellular process 1.5726E-3 2 250 2 6292
negative regulation of biological process 1.6107E-3 2 253 2 6292
mitotic cell cycle 1.6363E-3 2 255 2 6292
cellular macromolecular complex subunit organization 1.6882E-3 2 259 2 6292
mitotic anaphase B 1.9064E-3 2 6 1 6292
M phase 2.1762E-3 2 294 2 6292
anaphase 2.224E-3 2 7 1 6292
mitotic anaphase 2.224E-3 2 7 1 6292
macromolecular complex subunit organization 3.2108E-3 2 357 2 6292
cell cycle phase 3.5621E-3 2 376 2 6292
cell cycle process 6.0534E-3 2 490 2 6292
mitotic cell cycle spindle assembly checkpoint 6.6645E-3 2 21 1 6292
negative regulation of mitotic metaphase/anaphase transition 6.6645E-3 2 21 1 6292
spindle assembly checkpoint 6.6645E-3 2 21 1 6292
negative regulation of nuclear division 6.6645E-3 2 21 1 6292
negative regulation of mitosis 6.6645E-3 2 21 1 6292
cell cycle 6.95E-3 2 525 2 6292
negative regulation of cell cycle 6.9813E-3 2 22 1 6292
microtubule nucleation 7.2981E-3 2 23 1 6292
mitotic sister chromatid cohesion 7.2981E-3 2 23 1 6292
intracellular transport 7.7118E-3 2 553 2 6292
regulation of mitotic metaphase/anaphase transition 7.9314E-3 2 25 1 6292
mitotic cell cycle spindle checkpoint 7.9314E-3 2 25 1 6292
spindle checkpoint 7.9314E-3 2 25 1 6292
mitotic cell cycle checkpoint 8.8811E-3 2 28 1 6292
establishment of localization in cell 9.0494E-3 2 599 2 6292
regulation of nuclear division 9.1975E-3 2 29 1 6292
regulation of mitosis 9.1975E-3 2 29 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

microtubule motor activity 3.1764E-3 2 10 1 6292
motor activity 5.7138E-3 2 18 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle