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Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 7 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
GLC7
  • protein phosphatase type 1 complex
  • mRNA cleavage and polyadenylation specificity factor complex
  • cellular bud neck
  • spindle pole body
  • nuclear outer membrane
  • nucleolus
  • mating projection base
  • mitotic cell cycle spindle assembly checkpoint
  • cell morphogenesis during vegetative growth
  • protein amino acid dephosphorylation
  • chromosome segregation
  • cell budding
  • cellular ion homeostasis
  • meiosis
  • regulation of carbohydrate metabolic process
  • ascospore formation
  • response to heat
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • glycogen metabolic process
  • termination of RNA polymerase II transcription, poly(A)-independent
  • histone dephosphorylation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • RNA binding
  • metal ion binding
  • hydrolase activity
  • PTA1
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA cleavage factor complex
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • tRNA processing
  • termination of RNA polymerase II transcription, poly(A)-independent
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • PTI1
  • nucleus
  • mRNA cleavage and polyadenylation specificity factor complex
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • termination of RNA polymerase II transcription, poly(A)-independent
  • mRNA polyadenylation
  • mRNA cleavage
  • snoRNA 3'-end processing
  • RNA binding
  • REF2
  • nucleus
  • mRNA cleavage and polyadenylation specificity factor complex
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • termination of RNA polymerase II transcription, poly(A)-independent
  • telomere maintenance
  • mRNA processing
  • snoRNA 3'-end processing
  • DNA binding
  • RNA binding
  • SSU72
  • nucleus
  • mRNA cleavage and polyadenylation specificity factor complex
  • nuclear outer membrane
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • termination of RNA polymerase II transcription, poly(A)-independent
  • snoRNA transcription
  • termination of RNA polymerase II transcription
  • transcription initiation from RNA polymerase II promoter
  • phosphoprotein phosphatase activity
  • RNA binding
  • protein tyrosine phosphatase activity
  • phosphoric ester hydrolase activity
  • SWD2
  • Set1C/COMPASS complex
  • mRNA cleavage and polyadenylation specificity factor complex
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • termination of RNA polymerase II transcription, poly(A)-independent
  • histone methylation
  • telomere maintenance
  • mRNA 3'-end processing
  • snoRNA 3'-end processing
  • histone methyltransferase activity (H3-K4 specific)
  • SYC1
  • nucleus
  • mRNA cleavage and polyadenylation specificity factor complex
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • termination of RNA polymerase II transcription, poly(A)-independent
  • RNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mRNA cleavage and polyadenylation specificity factor complex 8.335E-20 7 15 7 6292
    mRNA cleavage factor complex 1.0041E-18 7 20 7 6292
    nucleoplasm part 1.2489E-10 7 245 7 6292
    nucleoplasm 2.1199E-10 7 264 7 6292
    nuclear lumen 9.6025E-9 7 453 7 6292
    organelle lumen 1.3579E-7 7 660 7 6292
    intracellular organelle lumen 1.3579E-7 7 660 7 6292
    membrane-enclosed lumen 2.0537E-7 7 700 7 6292
    nuclear part 5.0081E-6 7 1103 7 6292
    protein complex 6.1975E-6 7 1137 7 6292
    macromolecular complex 7.9244E-5 7 1635 7 6292
    nucleus 3.7528E-4 7 2041 7 6292
    intracellular organelle part 8.2061E-4 7 2282 7 6292
    organelle part 8.2061E-4 7 2282 7 6292
    nuclear outer membrane 3.7089E-3 7 86 2 6292
    nuclear membrane 4.6971E-3 7 97 2 6292
    mating projection base 7.7654E-3 7 7 1 6292
    protein phosphatase type 1 complex 7.7654E-3 7 7 1 6292
    methyltransferase complex 8.8705E-3 7 8 1 6292
    Set1C/COMPASS complex 8.8705E-3 7 8 1 6292
    histone methyltransferase complex 8.8705E-3 7 8 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    termination of RNA polymerase II transcription, poly(A)-independent 4.663E-22 7 9 7 6292
    termination of RNA polymerase II transcription, poly(A)-coupled 1.5543E-21 7 10 7 6292
    termination of RNA polymerase II transcription 6.5266E-19 7 19 7 6292
    transcription termination 1.5061E-18 7 21 7 6292
    cellular protein complex disassembly 1.9922E-16 7 39 7 6292
    protein complex disassembly 1.9922E-16 7 39 7 6292
    cellular macromolecular complex disassembly 2.4148E-16 7 40 7 6292
    macromolecular complex disassembly 2.4148E-16 7 40 7 6292
    cellular component disassembly 4.9635E-16 7 44 7 6292
    cellular macromolecular complex subunit organization 1.8515E-10 7 259 7 6292
    transcription from RNA polymerase II promoter 1.1425E-9 7 335 7 6292
    snoRNA metabolic process 1.6328E-9 7 18 4 6292
    macromolecular complex subunit organization 1.7902E-9 7 357 7 6292
    snoRNA 3'-end processing 8.4265E-9 7 5 3 6292
    transcription, DNA-dependent 2.0077E-8 7 503 7 6292
    RNA biosynthetic process 2.1525E-8 7 508 7 6292
    snoRNA processing 2.9465E-8 7 7 3 6292
    transcription 3.8629E-8 7 552 7 6292
    RNA 3'-end processing 5.918E-8 7 42 4 6292
    ncRNA 3'-end processing 1.8476E-7 7 12 3 6292
    RNA metabolic process 1.8079E-6 7 954 7 6292
    ncRNA metabolic process 2.1485E-6 7 257 5 6292
    mRNA 3'-end processing 3.7409E-6 7 31 3 6292
    cellular macromolecule biosynthetic process 8.3828E-6 7 1187 7 6292
    macromolecule biosynthetic process 8.4824E-6 7 1189 7 6292
    mRNA processing 1.2011E-5 7 156 4 6292
    gene expression 1.4468E-5 7 1283 7 6292
    nucleic acid metabolic process 2.8759E-5 7 1415 7 6292
    mRNA metabolic process 4.1254E-5 7 213 4 6292
    ncRNA processing 4.2803E-5 7 215 4 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5.8565E-5 7 1566 7 6292
    cellular biosynthetic process 5.8828E-5 7 1567 7 6292
    cellular component organization 6.2893E-5 7 1582 7 6292
    biosynthetic process 6.8686E-5 7 1602 7 6292
    cellular nitrogen compound metabolic process 1.3822E-4 7 1770 7 6292
    nitrogen compound metabolic process 1.5014E-4 7 1791 7 6292
    mRNA polyadenylation 1.7981E-4 7 19 2 6292
    mRNA cleavage 3.1446E-4 7 25 2 6292
    RNA polyadenylation 3.4048E-4 7 26 2 6292
    RNA processing 3.9614E-4 7 380 4 6292
    cellular macromolecule metabolic process 8.282E-4 7 2285 7 6292
    macromolecule metabolic process 1.0051E-3 7 2349 7 6292
    nucleic acid phosphodiester bond hydrolysis 1.0729E-3 7 46 2 6292
    snoRNA transcription 1.1125E-3 7 1 1 6292
    histone dephosphorylation 2.224E-3 7 2 1 6292
    covalent chromatin modification 3.8803E-3 7 88 2 6292
    histone modification 3.8803E-3 7 88 2 6292
    primary metabolic process 4.3588E-3 7 2896 7 6292
    cellular metabolic process 6.026E-3 7 3033 7 6292
    homeostatic process 7.7826E-3 7 408 3 6292
    metabolic process 7.9792E-3 7 3157 7 6292
    cell morphogenesis during vegetative growth 9.9746E-3 7 9 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RNA binding 2.5214E-7 7 367 6 6292
    nucleic acid binding 8.7797E-6 7 666 6 6292
    binding 4.326E-4 7 1294 6 6292
    phosphoprotein phosphatase activity 9.3752E-4 7 43 2 6292
    phosphatase activity 3.7942E-3 7 87 2 6292
    phosphoric ester hydrolase activity 5.1826E-3 7 102 2 6292
    histone methyltransferase activity (H3-K4 specific) 8.8705E-3 7 8 1 6292
    histone methyltransferase activity 9.9746E-3 7 9 1 6292
    histone-lysine N-methyltransferase activity 9.9746E-3 7 9 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle