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Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together. A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal. A protein complex required for mRNA cleavage but not for poly(A) addition. That part of the nuclear content other than the chromosomes or the nucleolus. Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules. Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: mRNA cleavage factor complex
Acc: GO:0005849
Aspect: Cellular Component
Desc: Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules.
Proteins in PDR annotated with:
   This term: 30 [Search]
   Term or descendants: 92 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005849 - mRNA cleavage factor complex (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle