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Protein Overview: CDK5_RAT

General Information:
Name(s) found: CDK5_RAT [Swiss-Prot]
Description(s) found:
Found 17 descriptions.
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  • Cyclin-dependent-like kinase 5 OS=Rattus norvegicus GN=Cdk5 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 292 amino acids

    Gene Ontology:
    Cellular Component: nuclear part [IDA]
    neuronal cell body [IDA]
    [NOT]nucleolus [UNKNOWN]
    growth cone [IDA]
    nucleus [UNKNOWN][IDA]
    dendrite [IDA]
    cytoskeleton [IDA]
    cytoplasm [UNKNOWN][IDA]
    membrane [IDA]
    cytosol [UNKNOWN][IEA]
    cell junction [TAS]
    filopodium [UNKNOWN][IEA]
    neuromuscular junction [IDA]
    cyclin-dependent protein kinase 5 holoenzyme complex [IDA]
    axon [UNKNOWN][IDA]
    lamellipodium [UNKNOWN][IEA]
    Biological Process: embryonic development [IDA]
    protein amino acid autophosphorylation [IDA]
    visual learning [UNKNOWN][IEA]
    central nervous system neuron development [UNKNOWN][IEA]
    intracellular protein transport [UNKNOWN][IEA]
    associative learning [UNKNOWN][IEA]
    exocytosis [IMP]
    cortical actin cytoskeleton organization [IMP]
    nucleocytoplasmic transport [IMP]
    receptor catabolic process [UNKNOWN][IEA]
    forebrain development [UNKNOWN]
    synaptic vesicle endocytosis [IMP]
    axonogenesis [UNKNOWN]
    negative regulation of synaptic plasticity [UNKNOWN][IEA]
    apoptosis [UNKNOWN]
    regulated secretory pathway [IMP]
    regulation of synaptic plasticity [IMP]
    serine phosphorylation of STAT3 protein [UNKNOWN][IEA]
    negative regulation of protein ubiquitination [UNKNOWN][IEA]
    neuron apoptosis [UNKNOWN][IMP]
    regulation of postsynaptic membrane potential [UNKNOWN]
    negative regulation of protein export from nucleus [UNKNOWN][IEA]
    regulation of excitatory postsynaptic membrane potential [UNKNOWN][IEA]
    cerebellum development [UNKNOWN]
    neuron differentiation [UNKNOWN][IDA]
    response to cocaine [UNKNOWN]
    cerebral cortex development [UNKNOWN][IEA]
    receptor clustering [UNKNOWN][IEA]
    corpus callosum development [UNKNOWN][IEA]
    central nervous system development [TAS]
    positive regulation of protein kinase activity [UNKNOWN][IEA]
    sensory perception of pain [UNKNOWN][IEA]
    peptidyl-serine phosphorylation [IDA]
    regulation of cell migration [UNKNOWN][IEA]
    layer formation in the cerebral cortex [UNKNOWN][IEA]
    motor axon guidance [UNKNOWN][IEA]
    Schwann cell development [UNKNOWN][IEA]
    telencephalon development [UNKNOWN]
    response to wounding [IMP]
    negative regulation of cell cycle [UNKNOWN][IEA]
    neuron projection morphogenesis [IMP]
    protein amino acid phosphorylation [UNKNOWN][IDA]
    cerebellar cortex development [UNKNOWN][IEA]
    positive regulation of neuron apoptosis [IDA]
    cerebellar cortex formation [UNKNOWN][IEA]
    dendrite morphogenesis [UNKNOWN][IEA]
    cell division [IEA]
    neuron migration [UNKNOWN][IEA]
    synaptic transmission, dopaminergic [UNKNOWN][IEA]
    behavioral response to cocaine [UNKNOWN][IEA]
    cell migration [UNKNOWN]
    cell-matrix adhesion [UNKNOWN][IEA]
    neuron projection development [IMP]
    hippocampus development [UNKNOWN][IEA]
    positive regulation of calcium ion-dependent exocytosis [UNKNOWN][IEA]
    axon extension [TAS]
    skeletal muscle tissue development [UNKNOWN][IEP][TAS]
    synaptic transmission, glutamatergic [UNKNOWN][IEA]
    Molecular Function: ErbB-2 class receptor binding [ISS]
    protein kinase activity [UNKNOWN][IDA]
    ErbB-3 class receptor binding [ISS]
    cyclin-dependent protein kinase activity [UNKNOWN][IDA]
    protein serine/threonine kinase activity [UNKNOWN][IDA]
    nucleotide binding [IEA]
    tau-protein kinase activity [IDA]
    ATP binding [IEA]
    p53 binding [UNKNOWN][IEA]
    acetylcholine receptor activator activity [ISS]
    protein binding [UNKNOWN][IDA][IPI]
    transferase activity [IEA]
    kinase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKYEKLEKI GEGTYGTVFK AKNRETHEIV ALKRVRLDDD DEGVPSSALR EICLLKELKH  60
   61 KNIVRLHDVL HSDKKLTLVF EFCDQDLKKY FDSCNGDLDP EIVKSLLFQL LKGLGFCHSR 120
  121 NVLHRDLKPQ NLLINRNGEL KLADFGLARA FGIPVRCYSA EVVTLWYRPP DVLFGAKLYS 180
  181 TSIDMWSAGC IFAELANAGR PLFPGNDVDD QLKRIFRLLG TPTEEQWPAM TKLPDYKPYP 240
  241 MYPATTSLVN VVPKLNATGR DLLQNLLKCN PVQRISAEEA LQHPYFSDFC PP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle