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The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell. Complex formation involves dimerization of a receptor protein tyrosine kinase followed by the association of several different intracellular signaling molecules with the cytoplasmic tails of the receptors. The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway. Grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response. The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand. The accumulation of acetylcholine receptors (AChRs) in a narrow, central region of muscle fibers, in apposition to nerve terminals. The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: receptor clustering
Acc: GO:0043113
Aspect: Biological Process
Desc: Grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
Proteins in PDR annotated with:
   This term: 38 [Search]
   Term or descendants: 38 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043113 - receptor clustering (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle