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Protein Overview: LONM4_ARATH

General Information:
Name(s) found: LONM4_ARATH [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Lon protease homolog 4, chloroplastic/mitochondrial OS=Arabidopsis thaliana GN=LON4 PE=3 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 942 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IDA]
    mitochondrion [IDA]
    Biological Process: proteolysis [IEA]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA][ISS]
    serine-type endopeptidase activity [IEA]
    serine-type peptidase activity [ISS]
    nucleoside-triphosphatase activity [IEA]
    ATP-dependent peptidase activity [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKFLTPTAY ASHHVTPATR FRSTPVKNLL FKQLTLLTGW NRSSYELGRR SFSSDLDSDT  60
   61 KSSTTTVSAK PHLDDCLTVI ALPLPHKPLI PGFYMPIYVK DPKVLAALQE SRRQQAPYAG 120
  121 AFLLKDDASS DSSSSSETEN ILEKLKGKEL INRIHEVGTL AQISSIQGEQ VILIGHRQLR 180
  181 ITEMVSESED PLTVKVDHLK DKPYDKDDDV IKATYFQVMS TLRDVLKTTS LWRDHVRTYT 240
  241 QACSLHIWHC LRHIGEFNYP KLADFGAGIS GANKHQNQGV LEELDVHKRL ELTLELVKKE 300
  301 VEINKIQESI AKAVEEKFSG DRRRIILKEQ INAIKKELGG ETDSKSALSE KFRGRIDPIK 360
  361 DKIPGHVLKV IEEELKKLQL LETSSSEFDV TCNYLDWLTV LPWGNFSDEN FNVLRAEKIL 420
  421 DEDHYGLSDV KERILEFIAV GGLRGTSQGK IICLSGPTGV GKTSIGRSIA RALDRKFFRF 480
  481 SVGGLSDVAE IKGHRRTYIG AMPGKMVQCL KNVGTENPLV LIDEIDKLGV RGHHGDPASA 540
  541 MLELLDPEQN ANFLDHYLDV PIDLSKVLFV CTANVTDTIP GPLLDRMEVI TLSGYITDEK 600
  601 MHIARDYLEK TARRDCGIKP EQVDVSDAAF LSLIEHYCRE AGVRNLQKQI EKIFRKIALK 660
  661 LVRKAASTEV PRISDDVTTD TEETKSLAKT DLESPETSAE GSTVLTDELA TGDPTESTTE 720
  721 QSGEVAETVE KYMIDESNLS DYVGKPVFQE EKIYEQTPVG VVMGLAWTSM GGSTLYIETT 780
  781 FVEEGEGKGG LHITGRLGDV MKESAEIAHT VARRIMLEKE PENKLFANSK LHLHVPAGAT 840
  841 PKDGPSAGCT MITSLLSLAL KKPVRKDLAM TGEVTLTGRI LAIGGVKEKT IAARRSQVKV 900
  901 IIFPEANRRD FDELARNVKE GLEVHFVDEY EQIFELAFGY DH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..691] PSI-BLAST 110.0 Crystal Structure Analysis of ClpB
    2 View Details [692..746] PSI-BLAST 14.045757 ADP Bound E. coli Clamp Loader Complex
    3 View Details [747..942] PSI-BLAST 32.09691 Catalytic domain of E.coli Lon protease

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrogen ion transmembrane transporter activity
    		•  3.92757313803074 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  3.76622182173583 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  3.49412822840068 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.46458392648207 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.411171656739 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.09072076169796 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  2.99135301692379 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.92624263342912 bayes_pls_golite062009
  • hydrolase activity
    		•  2.18454736627863 bayes_pls_golite062009
  • binding
    		•  2.0681607836408 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.84050240798436 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.81138802583782 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.78927528875848 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.78903889318615 bayes_pls_golite062009
  • helicase activity
    		•  1.40781177352978 bayes_pls_golite062009
  • ATPase activity
    		•  1.18431260772292 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.09000822067541 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.86836375892673 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.569910969126728 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.568840867400671 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.568779924702229 bayes_pls_golite062009
  • nucleotide binding
    		•  0.564275755355315 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.5607032154839 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.5607032154839 bayes_pls_golite062009
  • motor activity
    		•  0.50661339105747 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.503971340374059 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.384988511775694 bayes_pls_golite062009
  • protein binding
    		•  0.193768631623192 bayes_pls_golite062009
  • ATP binding
    		•  0.1860481660648 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  0.175442402308287 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.152859582615242 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.138615225841109 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.133736530545575 bayes_pls_golite062009
  • DNA binding
    		•  0.111331583742205 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0700789521444061 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • mitochondrial heavy strand promoter sense binding
    		•  7.07169438832198 bayes_pls_golite062009
  • DNA polymerase binding
    		•  7.07169438832198 bayes_pls_golite062009
  • mitochondrial light strand promoter anti-sense binding
    		•  7.07169438832198 bayes_pls_golite062009
  • mitochondrial heavy strand promoter anti-sense binding
    		•  7.07169438832198 bayes_pls_golite062009
  • mitochondrial light strand promoter sense binding
    		•  7.07169438832198 bayes_pls_golite062009
  • ribonuclease activity
    		•  2.03745175432755 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.38482286547386 bayes_pls_golite062009
  • hydrolase activity
    		•  1.18773479836745 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  1.16726450662143 bayes_pls_golite062009
  • exoribonuclease activity
    		•  1.1604717842042 bayes_pls_golite062009
  • structural molecule activity
    		•  1.14918348313691 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.13566902804592 bayes_pls_golite062009
  • ATP-dependent peptidase activity
    		•  0.99253423929971 bayes_pls_golite062009
  • binding
    		•  0.923114523007774 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • peptidase activity
    		•  0.46678532223973 bayes_pls_golite062009
  • nuclease activity
    		•  0.315907493060144 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.227419965943609 bayes_pls_golite062009
  • protein binding
    		•  0.214066724623027 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.161393552073973 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.145830549540622 bayes_pls_golite062009
  • exonuclease activity
    		•  0.118186133308559 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.114504249104206 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.0709817198603016 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  6.9430052008157E-5 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle