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Protein Overview: C83B1_ARATH

General Information:
Name(s) found: C83B1_ARATH [Swiss-Prot]
Description(s) found:
Found 18 descriptions.
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  • Cytochrome P450 83B1 OS=Arabidopsis thaliana GN=CYP83B1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 499 amino acids

    Gene Ontology:
    Cellular Component: membrane [IDA]
    mitochondrion [IDA]
    endoplasmic reticulum [IDA]
    plasma membrane [IDA]
    Biological Process: callose deposition in cell wall during defense response [IMP]
    indole glucosinolate biosynthetic process [IDA]
    indoleacetic acid biosynthetic process [IMP]
    tryptophan biosynthetic process [IMP]
    adventitious root development [TAS]
    induced systemic resistance [IEP]
    shade avoidance [IMP]
    defense response to bacterium [IMP]
    response to red light [IMP]
    Molecular Function: oxygen binding [ISS]
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLLLIIAGL VAAAAFFFLR STTKKSLRLP PGPKGLPIIG NLHQMEKFNP QHFLFRLSKL  60
   61 YGPIFTMKIG GRRLAVISSA ELAKELLKTQ DLNFTARPLL KGQQTMSYQG RELGFGQYTA 120
  121 YYREMRKMCM VNLFSPNRVA SFRPVREEEC QRMMDKIYKA ADQSGTVDLS ELLLSFTNCV 180
  181 VCRQAFGKRY NEYGTEMKRF IDILYETQAL LGTLFFSDLF PYFGFLDNLT GLSARLKKAF 240
  241 KELDTYLQEL LDETLDPNRP KQETESFIDL LMQIYKDQPF SIKFTHENVK AMILDIVVPG 300
  301 TDTAAAVVVW AMTYLIKYPE AMKKAQDEVR SVIGDKGYVS EEDIPNLPYL KAVIKESLRL 360
  361 EPVIPILLHR ETIADAKIGG YDIPAKTIIQ VNAWAVSRDT AAWGDNPNEF IPERFMNEHK 420
  421 GVDFKGQDFE LLPFGSGRRM CPAMHLGIAM VEIPFANLLY KFDWSLPKGI KPEDIKMDVM 480
  481 TGLAMHKKEH LVLAPTKHI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..499] PSI-BLAST 111.0 Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arachidonic acid monooxygenase activity
    		•  6.76823710927794 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
    		•  6.3313834755701 bayes_pls_golite062009
  • monooxygenase activity
    		•  5.57229509004705 bayes_pls_golite062009
  • steroid hydroxylase activity
    		•  5.04794778387361 bayes_pls_golite062009
  • oxysterol 7-alpha-hydroxylase activity
    		•  5.03099580095037 bayes_pls_golite062009
  • arachidonic acid epoxygenase activity
    		•  4.80764258881036 bayes_pls_golite062009
  • electron carrier activity
    		•  4.64931978461551 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
    		•  4.64322346579269 bayes_pls_golite062009
  • steroid 17-alpha-monooxygenase activity
    		•  3.79253506790596 bayes_pls_golite062009
  • retinoic acid 4-hydroxylase activity
    		•  3.76307535769621 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.68151610133025 bayes_pls_golite062009
  • demethylase activity
    		•  3.40807632433846 bayes_pls_golite062009
  • oxygen binding
    		•  3.29945075872446 bayes_pls_golite062009
  • flavonoid 3'-monooxygenase activity
    		•  3.16634614522939 bayes_pls_golite062009
  • sterol 14-demethylase activity
    		•  2.94610675710811 bayes_pls_golite062009
  • retinoic acid binding
    		•  2.70323898361882 bayes_pls_golite062009
  • retinoid binding
    		•  2.60220937953757 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    		•  2.56821164444595 bayes_pls_golite062009
  • isoprenoid binding
    		•  2.47826119804163 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.35847923992364 bayes_pls_golite062009
  • steroid 7-alpha-hydroxylase activity
    		•  2.29989218606587 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
    		•  2.15105968497418 bayes_pls_golite062009
  • ecdysteroid 25-hydroxylase activity
    		•  2.0071742914584 bayes_pls_golite062009
  • vitamin D 24-hydroxylase activity
    		•  1.81919676974797 bayes_pls_golite062009
  • vitamin D3 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • vitamin D 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • corticosterone 18-monooxygenase activity
    		•  1.64204907906991 bayes_pls_golite062009
  • steroid 11-beta-monooxygenase activity
    		•  1.64204907906991 bayes_pls_golite062009
  • ecdysteroid 22-hydroxylase activity
    		•  1.58167166311061 bayes_pls_golite062009
  • arachidonic acid 11,12-epoxygenase activity
    		•  1.48500938886158 bayes_pls_golite062009
  • testosterone 6-beta-hydroxylase activity
    		•  1.4661447981611 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  1.42927429551354 bayes_pls_golite062009
  • binding
    		•  1.2866152532988 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors
    		•  1.19694314158072 bayes_pls_golite062009
  • 25-hydroxycholecalciferol-24-hydroxylase activity
    		•  1.06487564122685 bayes_pls_golite062009
  • protein binding
    		•  0.836411857417911 bayes_pls_golite062009
  • catalytic activity
    		•  0.608111453189583 bayes_pls_golite062009
  • cholesterol monooxygenase (side-chain-cleaving) activity
    		•  0.276594551871869 bayes_pls_golite062009
  • 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
    		•  0.203772707673481 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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