Protein Overview: cyp-13B1

General Information:
Name(s) found:	cyp-13B1 / CE09177 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00008519 locus:cyp-13B1 Putative cytochrome P450 cyp-13B1 status:Partially_confirmed UniProt:O17624 protein_id:CAA91023.1 [WormBase] pir\|\|T19575 hypothetical protein F02C12.5a - Caenorhabditis elegans [NCBI NR] gi\|62901495\|sp\|O17624.2\|C13B1_CAEEL RecName: Full=Putative cytochrome P450 cyp-13B1 [NCBI NR] gi\|3875529\|emb\|CAA91023.1\| C. elegans protein F02C12.5a, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|3874596\|emb\|CAB07330.1\| C. elegans protein F02C12.5a, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|17551420\|ref\|NP_510232.1\| CYtochrome P450 family member (cyp-13B1) [Caenorhabditis elegans] [NCBI NR] Putative cytochrome P450 cyp-13B1 OS=Caenorhabditis elegans GN=cyp-13B1 PE=3 SV=2 [Swiss-Prot] [wormpep67.fasta] CE09177 WBGene00008519 locus:cyp-13B1 cytochrome P450 status:Partially_confirmed SW:O17624 protein_id:CAA91023.1 [wormpep150.fasta] 09177 WBGene00008519 cytochrome P450 status:Partially_confirmed TR:O17624 protein_id:CAA91023.1 [wormpep130-phg-ecoli-orf-rand.fasta] cytochrome P450 family member (XO26) [Caenorhabditis elegans]gi\|3874596\|emb\|CAB07330.1\| Hypothetical protein F02C12.5a [Caenorhabditis elegans]gi\|3875529\|emb\|CAA91023.1\| Hypothetical protein F02C12.5a [Caenorhabditis elegans]gi\|7498460\|pir\|\|T19575 hypo [nrdb_11152004_Chlamydomonas] CE09177 WBGene00008519 cytochrome P450 status:Partially_confirmed TR:O17624 protein_id:CAA91023.1 [wormpep132.fasta] 09177 WBGene00008519 locus:cyp-13B1 cytochrome P450 status:Partially_confirmed SW:O17624 protein_id:CAA91023.1 [wormpep150-phg-orf-ecoli-rand.fasta] CE09177 WBGene00008519 locus:cyp-13B1 cytochrome P450 status:Partially_confirmed TR:O17624 protein_id:CAA91023.1 [WormBase_C-elegans_na_01-20-2005_combined_reversed.fasta] cytochrome P450 status:Partially_confirmed TR:O17624 protein_id:CAA91023.1 [wormpep115.fasta.reversed] CE09177 cytochrome P450 status:Partially_confirmed TR:O17624 protein_id:CAA91023.1 [wormpep80.hongbin] CE09177 WBGene00008519 locus:cyp-13B1 cytochrome P450 status:Partially_confirmed UniProt:O17624 protein_id:CAB07330.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE09177 WBGene00008519 locus:cyp-13B1 cytochrome P450 status:Partially_confirmed UniProt:O17624 protein_id:CAB07330.1\| [wormORF-contam.fasta] Hypothetical protein F02C12.5a [Caenorhabditis elegans] [nr-271106-contam.fasta] CYtochrome P450 family member (cyp-13B1) [Caenorhabditis elegans] [nr-271106-contam.fasta] Putative cytochrome P450 cyp-13B1 [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE09177 WBGene00008519 locus:cyp-13B1 cytochrome P450 status:Partially_confirmed UniProt:O17624 protein_id:CAA91023.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE09177 WBGene00008519 locus:cyp-13B1 status:Partially_confirmed UniProt:O17624 protein_id:CAA91023.1 Putative cytochrome P450 cyp-13B1 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	527 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [IEA]
Biological Process:	electron transport [IEA]
Molecular Function:	iron ion binding [IEA] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [IEA] monooxygenase activity [IEA] heme binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGAIIVLVVL FATIAGYFKW IHTYWRRRGI SGPEGLPFIG NYYDLADVNK PRGYLIHKWT  60
   61 QKFGKVFGYY EGAVPVLVVS DMDMLQELFL KKFDNFYARK STNHIHGNLE CSKSEPRINL 120
  121 FTSRGARWKR LRALASPGFS VKALKQVHDV MEDSAINMVD LMAKHEDGKP FNIHAYFQEF 180
  181 TYDVISRLAM GQPNSELFNN SGVEIVKSIF MRTHRVLPWY FTVLFPQFEH LVKRMFYNHA 240
  241 AVQGGDIEKL LLICKKTVES RIQEREENAK LGFENAENDF IDMFLNYYSE QVEDIEFGST 300
  301 VEKKVTAEDV IGACFVFLLA GFDTTANSLA YASYLLAKHP EKMKLAQEEV DTVVGSENVS 360
  361 YDDMTKLKYL DAVVRESLRL YPVAWFACSR ECVKPTTLGD IYIDKGVKIE ADVMSLHRSK 420
  421 EIWGENADDF VPERWLEPSS RHTMSWIPFG AGPRQCVGMR LGLSEAKTAL AHLLRRYDLV 480
  481 AGVETEVRLT LRFFFIFKSS QIQKELNILG CTTTSPEAVT LYLKPRI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

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Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
arachidonic acid monooxygenase activity	6.76823710927794	bayes_pls_golite062009
fatty acid (omega-1)-hydroxylase activity	6.3313834755701	bayes_pls_golite062009
monooxygenase activity	5.57229509004705	bayes_pls_golite062009
steroid hydroxylase activity	5.04794778387361	bayes_pls_golite062009
arachidonic acid epoxygenase activity	4.80764258881036	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	4.64322346579269	bayes_pls_golite062009
steroid 17-alpha-monooxygenase activity	3.99744233006162	bayes_pls_golite062009
oxygen binding	3.7203678182299	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	3.68151610133025	bayes_pls_golite062009
demethylase activity	2.80780658333504	bayes_pls_golite062009
retinoic acid 4-hydroxylase activity	2.60901411823382	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2.56821164444595	bayes_pls_golite062009
thromboxane-A synthase activity	2.45281910634006	bayes_pls_golite062009
oxysterol 7-alpha-hydroxylase activity	2.36480328243514	bayes_pls_golite062009
oxidoreductase activity	2.35847923992364	bayes_pls_golite062009
sterol 14-demethylase activity	2.33937429425924	bayes_pls_golite062009
1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity	2.30416050662077	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen	2.15105968497418	bayes_pls_golite062009
ecdysteroid 25-hydroxylase activity	2.0071742914584	bayes_pls_golite062009
retinoid binding	1.91237853759594	bayes_pls_golite062009
vitamin D 24-hydroxylase activity	1.81919676974797	bayes_pls_golite062009
isoprenoid binding	1.78853880472253	bayes_pls_golite062009
flavonoid 3'-monooxygenase activity	1.71233606135238	bayes_pls_golite062009
retinoic acid binding	1.69236715381231	bayes_pls_golite062009
vitamin D3 25-hydroxylase activity	1.65825585934141	bayes_pls_golite062009
vitamin D 25-hydroxylase activity	1.65825585934141	bayes_pls_golite062009
corticosterone 18-monooxygenase activity	1.64204907906991	bayes_pls_golite062009
steroid 11-beta-monooxygenase activity	1.64204907906991	bayes_pls_golite062009
electron carrier activity	1.48516712188486	bayes_pls_golite062009
arachidonic acid 11,12-epoxygenase activity	1.48500938886158	bayes_pls_golite062009
testosterone 6-beta-hydroxylase activity	1.4661447981611	bayes_pls_golite062009
binding	1.2866152532988	bayes_pls_golite062009
25-hydroxycholecalciferol-24-hydroxylase activity	1.06487564122685	bayes_pls_golite062009
ecdysteroid 22-hydroxylase activity	0.7601272997427	bayes_pls_golite062009
catalytic activity	0.608111453189583	bayes_pls_golite062009
iron ion binding	0.529598228513719	bayes_pls_golite062009
cation binding	0.510556740388808	bayes_pls_golite062009
metal ion binding	0.510556740388808	bayes_pls_golite062009
ion binding	0.503326724714616	bayes_pls_golite062009
transition metal ion binding	0.450436868179747	bayes_pls_golite062009
cholesterol monooxygenase (side-chain-cleaving) activity	0.276594551871869	bayes_pls_golite062009

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..527]	PSI-BLAST	93.0	Crystal Structure of Human Microsomal P450 3A4

Protein Overview: cyp-13B1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: