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Protein Overview: SPBP22H7.05c

General Information:
Name(s) found: SPBP22H7.05c [Sanger Pombe]
Description(s) found:
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  • gi|74698051|sp|Q9C0W2.1|YHI5_SCHPO RecName: Full=Uncharacterized AAA domain-containing protein P22H7.05c [NCBI NR]
  • gi|19112394|ref|NP_595602.1| ATPase with bromodomain protein [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • gi|13810224|emb|CAC37373.1| ATPase with bromodomain protein [Schizosaccharomyces pombe] [NCBI NR]
  • ATPase with bromodomain protein [Sanger Pombe]
  • Uncharacterized AAA domain-containing protein P22H7.05c OS=Schizosaccharomyces pombe GN=SPBP22H7.05c PE=2 SV=1 [Swiss-Prot]
  • AAA FAMILY ATPASE; POSSIBLY IN ENDOPLASMIC RETICULUM: O13617;Q9C0W2; [pompepVF.fasta]
  • MEMBER OF THE AAA ATPASE FAMILY; POSSIBLY IN ENDOPLASMIC RETICULUM: O13617;Q9C0W2; [pompepV13]
  • Member of the AAA ATPase family, possibly in endoplasmic reticulum [pompep4896]
  • |||TAT-binding protein homolog [pompepnew.fasta]
  • SPBP22H7.05c protein (Pi026 protein) (Spactokyo_453.08 protein) [4896.FASTAC]
  • |||TAT-binding protein homolog|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • member of the AAA ATPase family; possibly in endoplasmic reticulum [Schizosaccharomyces pombe]gi|13810224|emb|CAC37373.1| SPBP22H7.05c [Schizosaccharomyces pombe] [nrdb_11152004_Chlamydomonas]
  • (Q9C0W2) Member of the AAA ATPase family, possibly in endoplasmic reticulum [pompep4896_normal_reversed]
  • |||ATPase with bromodomain protein|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPACTOKYO_453.08 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPBP22H7.05c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • |||ATPase with bromodomain protein |Schizosaccharomyces pombe|chr 2|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Uncharacterized AAA domain-containing protein P22H7.05c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pi026 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 1201 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear chromatin [ISSLink to PubMed article]
    Biological Process: chromatin remodeling [ISSLink to PubMed article]
    positive regulation of gene-specific transcription from RNA polymerase II promoter [ISS]
    Molecular Function: ATPase activity [ISSLink to PubMed article]
    ATP binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRRARSIRF SSDDNEDNEE DDDYYSNAHS EKSEDHSNHI KVSHFDPSSY KQKLVSVRET  60
   61 QRNRKFSSLQ KHLNTETPSF SVSIENPSKP SAAFNDASLG KKSTEHQIDG IRNGSSNLQM 120
  121 EGNDKELDTD NNEDESTTFK DEEDDLISPK SYLTSSKTFS YPKAPTESTN GDYLDEDYVD 180
  181 GQSDPESSNA SDSDFADSPD DLTKVRSPIP SRRGRRKRKM RGPILPVKKN LRVKKAMSPL 240
  241 RAERNSPDFR RKLRSRDNRP NYHLFDYYNE IASSPNPSTT KITYNPPKLP MKDFATLPIG 300
  301 YQSTCDSDET SELSSTSSEQ TSDVEGLNAY NNLGASSDIE NAPSSQLHFG HIDEKTIRST 360
  361 DPFANRENLD FNSIGGLEDI ILQLKEMVML PLLYPEVFLH LHITPPRGVL FHGPPGTGKT 420
  421 LMARVLAANC STKNQKISFF LRKGSDCLSK WVGEAERQLR LLFEEARRVQ PSIIFFDEID 480
  481 GLAPIRSSKQ EQTHSSIVST LLALMDGLDT RGQVVVIGAT NRPNDLDPAL RRPGRFDREF 540
  541 YFPLPNKQAR MKILEINSLH FSPKIPESYL LHLAESTSGY GGADLKALCT EAALNAVRRT 600
  601 FPQIYTSSDK FLIDLNEISV SICDFVVASE KIAVSTRRSD VKPNIPITDS HKILFKKSIE 660
  661 VITSKIRRLL KLDVYLPTVE SLQKLPAEEL MRQKEINSLK TTMSFRPRLL ITDIYGYGCT 720
  721 YLSKVLFSML DGIHVQSLDI SELLMDTTTS PRSLLTKIFS EARKNAPSII FINNVEKWPS 780
  781 LFSHSFLSMF LLLLDSISPL EPVMLLGFAN TNQEKLSSTV RSWFPSHRSE YHDLSFPDYS 840
  841 SRYSFFHYLL KRISFLPIHQ KSAEAASVDI LPKVLPVSKT SDLTDKVNRR QRKNDKKIKN 900
  901 KIQVKLSSIL EMLRSRYKKF KKPIIDLNDI YIDESNERVV KGKSKDNFEY FLSGNTVTRK 960
  961 KDNACFKMMN FEEIERRLWS GRYCTPKEFL RDIKMIKQDA ILSGDVNLKH KAKEMFAHAE1020
 1021 LNVDELIDAK LLYDCCQVSK REKAYKQLKQ KKLNNAKDAH EMQESKNEET FVRNDVAQED1080
 1081 NFIELSSNEV RNVSNDEHKH TLFHGQSLTH NNLIAVTPPS RTGVEHKEEN KKYDNVNIQK1140
 1141 TLAKCAEEFA EHTNFNKVEL LDFVYSKLSS TIWENREEHD LLKIVRDVRQ TFFRSLEDMG1200
 1201 V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)
    View Run dam1 No Comments Liu X, et al. (2005)
    View Run dam1 No Comments Liu X, et al. (2005)
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..185] PSI-BLAST 20.30103 ClpB
    2 View Details [186..920] PSI-BLAST 120.0 VCP/p97
    3 View Details [921..1201] PSI-BLAST 107.0 EDTA treated

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleoside-triphosphatase activity
    		•  3.35731768967288 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  3.27731862965146 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  3.25621165738898 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  3.25495234707235 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • motor activity
    		•  2.60481158518321 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  2.58390156971125 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.04687224697398 bayes_pls_golite062009
  • ATPase activity
    		•  2.04651885449197 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.99615042505049 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.87142752786895 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.8338258963054 bayes_pls_golite062009
  • microtubule motor activity
    		•  1.77441050776692 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  1.72558760441869 bayes_pls_golite062009
  • DNA helicase activity
    		•  1.72320119360938 bayes_pls_golite062009
  • hydrolase activity
    		•  1.6901766958628 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.54743962081773 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  1.52935820732225 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.50574672650697 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  1.44952193735984 bayes_pls_golite062009
  • helicase activity
    		•  1.33212695797068 bayes_pls_golite062009
  • microfilament motor activity
    		•  1.28029120876672 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  1.18729287682305 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.937312964541395 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.89390151223569 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.89390151223569 bayes_pls_golite062009
  • actin binding
    		•  0.875514430441177 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.777787753097919 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  0.707571682109441 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.579644950922817 bayes_pls_golite062009
  • DNA binding
    		•  0.479412476059825 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.464456497491373 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.434775387083003 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • transporter activity
    		•  0.39890191703346 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • potassium channel activity
    		•  0.312408775819051 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.312171320541728 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.307808489214465 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.294474570607914 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.282352478532746 bayes_pls_golite062009
  • tubulin binding
    		•  0.264882086048416 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.244430557819844 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.241122503584588 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  0.229994987891881 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.22939561735194 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.219533217661421 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.2192434828134 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.219157471322311 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • microtubule binding
    		•  0.156470772916507 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  0.148669680164146 bayes_pls_golite062009
  • GTPase activity
    		•  0.105546189348878 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  0.078513977233484 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  0.078513977233484 bayes_pls_golite062009
  • protein transporter activity
    		•  0.0071389922757723 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle