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View Structure Prediction Details

Protein: SPBP22H7.05c
Organism: Schizosaccharomyces pombe
Length: 1201 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBP22H7.05c.

Description E-value Query
Range		 Subject
Range
gi|2257509 - gi|2257509|dbj|BAA21405.1| TAT-BINDING HOMOLOG 7. [Schizosaccharomyces pombe]
 548.0 [0..1] [1201..41]
gi|18159541, gi|... - gi|18312110|ref|NP_558777.1| AAA family ATPase, CDC48 subfamily protein [Pyrobaculum aerophilum str....
 448.0 [0..365] [945..172]
gi|145010540, gi... - gi|39940094|ref|XP_359584.1| cell division control protein Cdc48 [Magnaporthe grisea 70-15], gb|EAA5...
 444.0 [0..187] [953..37]
CD48D_ARATH - Cell division control protein 48 homolog D OS=Arabidopsis thaliana GN=CDC48D PE=1 SV=1
 443.0 [0..166] [929..3]
CDC48_SOYBN - Cell division cycle protein 48 homolog OS=Glycine max GN=CDC48 PE=2 SV=1
 443.0 [0..186] [963..23]
YB56_METJA, Y115... - (Q58556) Cell division cycle protein 48 homolog MJ1156, Cell division cycle protein 48 homolog MJ115...
Y1156_METJA - Cell division cycle protein 48 homolog MJ1156 OS=Methanocaldococcus jannaschii (strain ATCC 43067 / ...
 443.0 [0..365] [1057..172]
gi|85082883 - gi|85082883|ref|XP_957005.1| hypothetical protein [Neurospora crassa OR74A]
gi|28918088, gi|... - gi|32402982|ref|XP_322104.1| hypothetical protein [Neurospora crassa], gi|28918088|gb|EAA27769.1| hy...
 443.0 [0..187] [953..39]
gi|119524342, gi... - gi|119719222|ref|YP_919717.1| AAA family ATPase, CDC48 subfamily protein [Thermofilum pendens Hrk 5]...
 442.0 [0..279] [937..91]
gi|98962497 - gi|98962497|gb|ABF59516.1| putative spindle disassembly related protein CDC48 [Nicotiana tabacum]
 440.0 [0..176] [963..13]
gi|73971214 - gi|73971214|ref|XP_866075.1| PREDICTED: similar to Transitional endoplasmic reticulum ATPase (TER AT...
 440.0 [0..193] [925..25]

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Predicted Domain #1
Region A:
Residues: [1-185] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRRARSIRF SSDDNEDNEE DDDYYSNAHS EKSEDHSNHI KVSHFDPSSY KQKLVSVRET  60
   61 QRNRKFSSLQ KHLNTETPSF SVSIENPSKP SAAFNDASLG KKSTEHQIDG IRNGSSNLQM 120
  121 EGNDKELDTD NNEDESTTFK DEEDDLISPK SYLTSSKTFS YPKAPTESTN GDYLDEDYVD 180
  181 GQSDP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.30103
Match: 1jbkA
Description: ClpB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleoside-triphosphatase activity 3.35731768967288 bayes_pls_golite062009
pyrophosphatase activity 3.27731862965146 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 3.25621165738898 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 3.25495234707235 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
motor activity 2.60481158518321 bayes_pls_golite062009
DNA-dependent ATPase activity 2.58390156971125 bayes_pls_golite062009
metal ion transmembrane transporter activity 2.04687224697398 bayes_pls_golite062009
ATPase activity 2.04651885449197 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.99615042505049 bayes_pls_golite062009
ATPase activity, coupled 1.87142752786895 bayes_pls_golite062009
ion transmembrane transporter activity 1.8338258963054 bayes_pls_golite062009
microtubule motor activity 1.77441050776692 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 1.72558760441869 bayes_pls_golite062009
DNA helicase activity 1.72320119360938 bayes_pls_golite062009
hydrolase activity 1.6901766958628 bayes_pls_golite062009
cation transmembrane transporter activity 1.54743962081773 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.52935820732225 bayes_pls_golite062009
cytoskeletal protein binding 1.50574672650697 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 1.44952193735984 bayes_pls_golite062009
helicase activity 1.33212695797068 bayes_pls_golite062009
microfilament motor activity 1.28029120876672 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 1.18729287682305 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.937312964541395 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.89390151223569 bayes_pls_golite062009
ATP-dependent helicase activity 0.89390151223569 bayes_pls_golite062009
actin binding 0.875514430441177 bayes_pls_golite062009
nucleic acid binding 0.777787753097919 bayes_pls_golite062009
protein-DNA loading ATPase activity 0.707571682109441 bayes_pls_golite062009
structure-specific DNA binding 0.579644950922817 bayes_pls_golite062009
DNA binding 0.479412476059825 bayes_pls_golite062009
substrate-specific transporter activity 0.464456497491373 bayes_pls_golite062009
active transmembrane transporter activity 0.434775387083003 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
transporter activity 0.39890191703346 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
potassium channel activity 0.312408775819051 bayes_pls_golite062009
transcription regulator activity 0.312171320541728 bayes_pls_golite062009
voltage-gated cation channel activity 0.307808489214465 bayes_pls_golite062009
primary active transmembrane transporter activity 0.294474570607914 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.282352478532746 bayes_pls_golite062009
tubulin binding 0.264882086048416 bayes_pls_golite062009
voltage-gated ion channel activity 0.244430557819844 bayes_pls_golite062009
voltage-gated channel activity 0.241122503584588 bayes_pls_golite062009
DNA clamp loader activity 0.229994987891881 bayes_pls_golite062009
transmembrane transporter activity 0.22939561735194 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.220608508617331 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.219533217661421 bayes_pls_golite062009
double-stranded DNA binding 0.2192434828134 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.219157471322311 bayes_pls_golite062009
protein binding 0.170837278876362 bayes_pls_golite062009
microtubule binding 0.156470772916507 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 0.148669680164146 bayes_pls_golite062009
GTPase activity 0.105546189348878 bayes_pls_golite062009
histone acetyltransferase activity 0.078513977233484 bayes_pls_golite062009
lysine N-acetyltransferase activity 0.078513977233484 bayes_pls_golite062009
protein transporter activity 0.0071389922757723 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [186-920] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESSNASDSDF ADSPDDLTKV RSPIPSRRGR RKRKMRGPIL PVKKNLRVKK AMSPLRAERN  60
   61 SPDFRRKLRS RDNRPNYHLF DYYNEIASSP NPSTTKITYN PPKLPMKDFA TLPIGYQSTC 120
  121 DSDETSELSS TSSEQTSDVE GLNAYNNLGA SSDIENAPSS QLHFGHIDEK TIRSTDPFAN 180
  181 RENLDFNSIG GLEDIILQLK EMVMLPLLYP EVFLHLHITP PRGVLFHGPP GTGKTLMARV 240
  241 LAANCSTKNQ KISFFLRKGS DCLSKWVGEA ERQLRLLFEE ARRVQPSIIF FDEIDGLAPI 300
  301 RSSKQEQTHS SIVSTLLALM DGLDTRGQVV VIGATNRPND LDPALRRPGR FDREFYFPLP 360
  361 NKQARMKILE INSLHFSPKI PESYLLHLAE STSGYGGADL KALCTEAALN AVRRTFPQIY 420
  421 TSSDKFLIDL NEISVSICDF VVASEKIAVS TRRSDVKPNI PITDSHKILF KKSIEVITSK 480
  481 IRRLLKLDVY LPTVESLQKL PAEELMRQKE INSLKTTMSF RPRLLITDIY GYGCTYLSKV 540
  541 LFSMLDGIHV QSLDISELLM DTTTSPRSLL TKIFSEARKN APSIIFINNV EKWPSLFSHS 600
  601 FLSMFLLLLD SISPLEPVML LGFANTNQEK LSSTVRSWFP SHRSEYHDLS FPDYSSRYSF 660
  661 FHYLLKRISF LPIHQKSAEA ASVDILPKVL PVSKTSDLTD KVNRRQRKND KKIKNKIQVK 720
  721 LSSILEMLRS RYKKF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 120.0
Match: 1oz4A
Description: VCP/p97
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [921-1201] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKPIIDLNDI YIDESNERVV KGKSKDNFEY FLSGNTVTRK KDNACFKMMN FEEIERRLWS  60
   61 GRYCTPKEFL RDIKMIKQDA ILSGDVNLKH KAKEMFAHAE LNVDELIDAK LLYDCCQVSK 120
  121 REKAYKQLKQ KKLNNAKDAH EMQESKNEET FVRNDVAQED NFIELSSNEV RNVSNDEHKH 180
  181 TLFHGQSLTH NNLIAVTPPS RTGVEHKEEN KKYDNVNIQK TLAKCAEEFA EHTNFNKVEL 240
  241 LDFVYSKLSS TIWENREEHD LLKIVRDVRQ TFFRSLEDMG V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 107.0
Match: 2ce7A
Description: EDTA treated
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle