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Protein Overview: FBpp0303704, FBp...

General Information:
Name(s) found: FBpp0303710 [FlyBase]
FBpp0303704 [FlyBase]
FBpp0303697 [FlyBase]
Description(s) found:
Found 48 descriptions.
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  • type=protein; loc=X:complement(6978561..6978852,6979191..6979372,6979443..6979550,6979652..6980011,6981647..6981692,6985707..6985783); ID=FBpp0303710; name=Sxl-PT; parent=FBgn0264270,FBtr0331268; dbxref=REFSEQ:NP_001162690,GB_protein:ACZ95226,FlyBase_Annotation_IDs:CG43770-PT,FlyBase:FBpp0303710; MD5=e5b97aa1646c72bde4396bce68b88e9a; length=354; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:complement(6978561..6978852,6979191..6979372,6979443..6979550,6979652..6980011,6981647..6981692,6985707..6985783); ID=FBpp0303704; name=Sxl-PD; parent=FBgn0264270,FBtr0331262; dbxref=REFSEQ:NP_727162,GB_protein:AAG22410,FlyBase_Annotation_IDs:CG43770-PD,FlyBase:FBpp0303704; MD5=e5b97aa1646c72bde4396bce68b88e9a; length=354; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:complement(6978561..6978852,6979191..6979372,6979443..6979550,6979652..6980011,6981647..6981692,6985707..6985783); ID=FBpp0303697; name=Sxl-PL; parent=FBgn0264270,FBtr0331255; dbxref=REFSEQ:NP_001027065,GB_protein:AAZ52511,FlyBase_Annotation_IDs:CG43770-PL,FlyBase:FBpp0303697; MD5=e5b97aa1646c72bde4396bce68b88e9a; length=354; release=r5.56; species=Dmel; [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 354 amino acids

    Gene Ontology:
    Cellular Component: protein complex [IPI]
    Biological Process: germ cell development [TAS]
    reciprocal meiotic recombination [TAS]
    smoothened signaling pathway [IDA]
    oocyte differentiation [IDA]
    sex determination, primary response to X:A ratio [NAS][TAS]
    sex determination [NAS][TAS]
    nuclear mRNA splicing, via spliceosome [TAS]
    imaginal disc growth [IMP]
    sex differentiation [NAS][TAS]
    dosage compensation [NAS][TAS]
    oogenesis [TAS]
    negative regulation of nuclear mRNA splicing, via spliceosome [TAS]
    alternative nuclear mRNA splicing, via spliceosome [TAS]
    regulation of nuclear mRNA splicing, via spliceosome [NAS][TAS]
    female germ-line sex determination [TAS]
    female somatic sex determination [TAS]
    somatic sex determination [NAS][TAS]
    negative regulation of translation [IDA][IMP][NAS][TAS]
    female sex determination [NAS]
    Molecular Function: nucleotide binding [IEA]
    growth factor activity [IDA]
    protein binding [IPI]
    mRNA 5'-UTR binding [IDA][TAS]
    poly-pyrimidine tract binding [IDA]
    translation repressor activity, nucleic acid binding [TAS]
    mRNA binding [ISS][TAS]
    poly(U) RNA binding [IDA]
    mRNA 3'-UTR binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYGNNNPGSN NNNGGYPPYG YNNKSSGGRG FGMSHSLPSG MSRYAFSPQD TEFSFPSSSS  60
   61 RRGYNDFPGC GGSGGNGGSA NNLGGGNMCH LPPMASNNSL NNLCGLSLGS GGSDDLMNDP 120
  121 RASNTNLIVN YLPQDMTDRE LYALFRAIGP INTCRIMRDY KTGYSFGYAF VDFTSEMDSQ 180
  181 RAIKVLNGIT VRNKRLKVSY ARPGGESIKD TNLYVTNLPR TITDDQLDTI FGKYGSIVQK 240
  241 NILRDKLTGR PRGVAFVRYN KREEAQEAIS ALNNVIPEGG SQPLSVRLAE EHGKAKAAHF 300
  301 MSQMGVVPAN VPPPPPQPPA HMAAAFNMMH RGRSIKSQQR FQNSHPYFDA KKFI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..118] deduced N/A No confident structure predictions are available.
    2 View Details [119..354] PSI-BLAST 40.69897 Sex-lethal protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • RNA binding
    		•  6.73097473547076 bayes_pls_golite062009
    		• 6.62953239642182 bayes_pls_golite062009
  • mRNA binding
    		•  5.29759606920196 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.92126426323641 bayes_pls_golite062009
  • snRNA binding
    		•  4.06596327298973 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  3.11990160533699 bayes_pls_golite062009
  • U1 snRNA binding
    		•  3.02511982045347 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  2.93798024346416 bayes_pls_golite062009
  • structural molecule activity
    		•  2.78501986457503 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.18211199677674 bayes_pls_golite062009
  • DNA binding
    		•  1.8021593476478 bayes_pls_golite062009
  • U2 snRNA binding
    		•  1.34078165372485 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.06887262556449 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.970421843909091 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.87522799562879 bayes_pls_golite062009
  • transcription factor activity
    		•  0.873765500321315 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.824614388276642 bayes_pls_golite062009
  • mRNA 5'-UTR binding
    		•  0.625848256054783 bayes_pls_golite062009
  • translation regulator activity
    		•  0.583455818533482 bayes_pls_golite062009
  • translation repressor activity, nucleic acid binding
    		•  0.461000905454505 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.383589644462932 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.333822192939807 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle