YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism. Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism. Any process that stops, prevents or reduces the frequency, rate or extent of RNA splicing. The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA. Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide. Any process that stops, prevents or reduces the frequency, rate or extent of mRNA processing. Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of nuclear mRNA splicing, via spliceosome
Acc: GO:0048025
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.
Synonyms:
  • down-regulation of nuclear mRNA splicing via U2-type spliceosome
  • GO:0035056
  • down regulation of nuclear mRNA splicing via U2-type spliceosome
  • negative regulation of pre-mRNA splicing
  • negative regulation of nuclear mRNA splicing via U2-type spliceosome
  • down-regulation of nuclear mRNA splicing, via spliceosome
  • down regulation of nuclear mRNA splicing, via spliceosome
  • inhibition of nuclear mRNA splicing, via spliceosome
  • inhibition of nuclear mRNA splicing via U2-type spliceosome
  • downregulation of nuclear mRNA splicing, via spliceosome
  • downregulation of nuclear mRNA splicing via U2-type spliceosome
Proteins in PDR annotated with:
   This term: 12 [Search]
   Term or descendants: 12 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048025 - negative regulation of nuclear mRNA splicing, via spliceosome (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle