Protein Overview: FBpp0292319, ttk...

General Information:
Name(s) found:	FBpp0292319 [FlyBase] ttk-PA / FBpp0085190 [FlyBase] ttk-PB / FBpp0085188 [FlyBase] ttk-PE / FBpp0085186 [FlyBase]
Description(s) found: Found 55 descriptions. SHOW ALL	type=protein; loc=3R:join(27553013..27553156,27553344..27553976,27554114..27554201,27558642..27560218); ID=FBpp0292319; name=ttk-PG; parent=FBgn0003870,FBtr0303227; dbxref=FlyBase:FBpp0292319,FlyBase_Annotation_IDs:CG1856-PG,REFSEQ:NP_001189329,GB_protein:ADV37419; MD5=6d0c8c062eaa9ffa3dc54ae46ec6c960; length=813; release=r5.56; species=Dmel; [FlyBase] The gene tramtrack is referred to in FlyBase by the symbol Dmel\ttk (CG1856, FBgn0003870). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27539606..27561114. It has the cytological map location 100D1. There is experimental evidence that it has the molecular function</span>: protein binding; specific transcriptional repressor activity; chromatin binding; protein homodimerization activity. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior; startle response; brain morphogenesis; dendrite morphogenesis; neuron development; ovarian follicle cell development; negative regulation of transcription, DNA-dependent; dorsal appendage formation; locomotion involved in locomotory behavior. 152 alleles are reported. The phenotypes of these alleles are annotated with 70 unique terms, many of which group under: peripheral nervous system; nervous system; external compound sense organ; adult segment; embryonic nervous system; multi-cell-component structure; adult mesothoracic segment; embryonic glial cell; imaginal precursor; larval abdominal segment 5. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] The gene tramtrack is referred to in FlyBase by the symbol Dmel\ttk (CG1856, FBgn0003870). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27539606..27561114. It has the cytological map location 100D1. There is experimental evidence that it has the molecular function</span>: protein binding; specific transcriptional repressor activity; chromatin binding; protein homodimerization activity. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior; startle response; brain morphogenesis; dendrite morphogenesis; neuron development; ovarian follicle cell development; negative regulation of transcription, DNA-dependent; dorsal appendage formation; locomotion involved in locomotory behavior. 152 alleles are reported. The phenotypes of these alleles are annotated with 70 unique terms, many of which group under: peripheral nervous system; nervous system; external compound sense organ; adult segment; embryonic nervous system; multi-cell-component structure; adult mesothoracic segment; embryonic glial cell; imaginal precursor; larval abdominal segment 5. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] The gene tramtrack is referred to in FlyBase by the symbol Dmel\ttk (CG1856, FBgn0003870). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27539606..27561114. It has the cytological map location 100D1. There is experimental evidence that it has the molecular function</span>: protein binding; specific transcriptional repressor activity; chromatin binding; protein homodimerization activity. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior; startle response; brain morphogenesis; dendrite morphogenesis; neuron development; ovarian follicle cell development; negative regulation of transcription, DNA-dependent; dorsal appendage formation; locomotion involved in locomotory behavior. 152 alleles are reported. The phenotypes of these alleles are annotated with 70 unique terms, many of which group under: peripheral nervous system; nervous system; external compound sense organ; adult segment; embryonic nervous system; multi-cell-component structure; adult mesothoracic segment; embryonic glial cell; imaginal precursor; larval abdominal segment 5. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	813 amino acids
Gene Ontology:
Cellular Component:	nucleus [NAS] polytene chromosome [IDA]
Biological Process:	regulation of cell shape [IMP] R7 cell development [TAS] peripheral nervous system development [TAS] dorsal appendage formation [IMP] brain morphogenesis [IMP] neuron development [IMP] inter-male aggressive behavior [IMP] regulation of transcription from RNA polymerase II promoter [NAS] dendrite morphogenesis [IMP] negative regulation of transcription from RNA polymerase II promoter [NAS] locomotion involved in locomotory behavior [IMP] negative regulation of transcription, DNA-dependent [IDA] startle response [IMP] ovarian follicle cell development [IMP] cell fate determination [TAS]
Molecular Function:	DNA binding [IEA] zinc ion binding [IEA] protein homodimerization activity [IPI] protein binding [IPI] specific RNA polymerase II transcription factor activity [NAS] chromatin binding [IDA] transcription repressor activity [NAS] specific transcriptional repressor activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKMASQRFCL RWNNHQSNLL SVFDQLLHAE TFTDVTLAVE GQHLKAHKMV LSACSPYFNT  60
   61 LFVSHPEKHP IVILKDVPYS DMKSLLDFMY RGEVSVDQER LTAFLRVAES LRIKGLTEVN 120
  121 DDKPSPAAAA AGAGATGSES TATTPQLQRI QPYLVPQRNR SQAGGLLASA ANAGNTPTLP 180
  181 VQPSLLSSAL MPKRKRGRPR KLSGSSNGTG NDYDDFDREN MMNDSSDLGN GKMCNESYSG 240
  241 NDDGSDDNQP NAGHTDDLNE SRDSLPSKRS KNSKDHRVVS HHEDNSTSVT PTKATPELSQ 300
  301 RLFGSSSTTI SATAPGGSST GPSETISLLE ISDERESAPV HLPTILGLKI RAINTTTPAQ 360
  361 QGSPQTPTKS KPKIRQATGS NNSNSLLKQQ LRGGAKDPEV PPATRITGAV TPNAALNAEE 420
  421 QSKEMPKKNQ DEVNACIGLH SLANAAEQQA AQVASTGNLH HQLLLHMAAN NSMLNTTDYY 480
  481 QQQQQESPSS AGQFMDDDLE LLSLNDQQDK SDEPDHEMVT LADENAGLPG YQGNEAEATP 540
  541 AQEDSPAAET ATAPPPAPRS GKKGAKRPIQ RRRVRRKAQS TLDDQAEHLT EMSVRGLDLF 600
  601 RYASVVEGVY RCTECAKENM QKTFKNKYSF QRHAFLYHEG KHRKVFPCPV CSKEFSRPDK 660
  661 MKNHLKMTHE NFTPPKDIGA FSPLKYLISA AAAGDMHATI YQQQQDHYHR QLAEQLEQQN 720
  721 ASFDSRDSSL ILPDVKMEHA EDQDAEQEAE LSDGGYDASN PAAAAAAMLS LQQDVIIKDE 780
  781 IQISPSPSPT PPASCAVAEG KSLALASTAQ TAT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..133]	PSI-BLAST	23.0	Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB domain to 2.2 Angstrom
2	View Details	[134..298]	deduced	N/A	No confident structure predictions are available.
3	View Details	[299..392]	deduced	N/A	No confident structure predictions are available.
4	View Details	[393..607]	PSI-BLAST	37.0	No description for 2i13A was found.
5	View Details	[608..813]	PSI-BLAST	10.69897	Five-finger GLI1

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Protein Overview: FBpp0292319, ttk...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: