YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: hppy-PA

General Information:
Name(s) found: hppy-PA / FBpp0085692 [FlyBase]
Description(s) found:
SHOW ONLY BEST
  • gi|7302511|gb|AAF57595.1| CG7097, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|24655504|ref|NP_725863.1| CG7097, isoform A [Drosophila melanogaster] [NCBI NR]
  • The gene happyhour is referred to in FlyBase by the symbol Dmel\hppy (CG7097, FBgn0034421). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15066259..15114705. It has the cytological map location 56C1-56C4. There is experimental evidence that it has the molecular function</span>: protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of TOR signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; protein amino acid phosphorylation; behavioral response to ethanol. 17 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG7097-PA translation from_gene[CG7097 CG7097 FBgn0034421] seq_release:3 mol_weight=132397 cds_boundaries:(2R:14,243,453..14,289,856[+]) aa_length:1218 transcript_info:[CG7097-RA seq_release:3] gene_info:[gene symbol:CG7097 FBgn0034421 gene_boundaries [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V8R6) CG7097 protein [DrosMelano7227.FASTAC.txt]
  • (AE003796) CG7097 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG7097-PA, isoform A [Drosophila melanogaster]gi|24655504|ref|NP_725863.1| CG7097-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(15067238..15067363,15099361..15099781,15103926..15104024,15104248..15104546,15105262..15105349,15105636..15105699,15108249..15108287,15110745..15111891,15111955..15112081,15112146..15112499,15112565..15113008,15113070..15113291,1 [fly-100309-contam.fasta]
  • CG7097-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(15067238..15067363,15099361..15099781,15103926..15104024,15104248..15104546,15105262..15105349,15105636..15105699,15108249..15108287,15110745..15111891,15111955..15112081,15112146..15112499,15112565..15113008,15113070..15113291,15113352..15113478,15113545..15113644); ID=FBpp0085692; name=CG7097-PA; parent=FBgn0034421,FBtr0086504; dbxref=FlyBase:FBpp0085692,FlyBase_Annotation_IDs:CG7097-PA,GB_protein:AAF57595.1,REFSEQ:NP_725863,GB_protein:AAF57595; MD5=8fee56e25c8d9b56f77672788da67029; length=1218; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(15067238..15067363,15099361..15099781,15103926..15104024,15104248..15104546,15105262..15105349,15105636..15105699,15108249..15108287,15110745..15111891,15111955..15112081,15112146..15112499,15112565..15113008,15113070..15113291,15113352..15113478,15113545..15113644); ID=FBpp0085692; name=hppy-PA; parent=FBgn0034421,FBtr0086504; dbxref=FlyBase:FBpp0085692,FlyBase_Annotation_IDs:CG7097-PA,GB_protein:AAF57595.1,REFSEQ:NP_725863,GB_protein:AAF57595; MD5=8fee56e25c8d9b56f77672788da67029; length=1218; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Happyhour, isoform A OS=Drosophila melanogaster GN=hppy PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:join(15067238..15067363,15099361..15099781,15103926..15104024,15104248..15104546,15105262..15105349,15105636..15105699,15108249..15108287,15110745..15111891,15111955..15112081,15112146..15112499,15112565..15113008,15113070..15113291,15113352..15113478,15113545..15113644); ID=FBpp0085692; name=hppy-PA; parent=FBgn0263395,FBtr0086504; dbxref=FlyBase:FBpp0085692,FlyBase_Annotation_IDs:CG7097-PA,GB_protein:AAF57595.1,REFSEQ:NP_725863,GB_protein:AAF57595,FlyMine:FBpp0085692,modMine:FBpp0085692; MD5=8fee56e25c8d9b56f77672788da67029; length=1218; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • Happyhour, isoform A OS=Drosophila melanogaster GN=hppy PE=4 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=2R:join(19179733..19179858,19211856..19212276,19216421..19216519,19216743..19217041,19217757..19217844,19218131..19218194,19220744..19220782,19223240..19224386,19224450..19224576,19224641..19224994,19225060..19225503,19225565..19225786,19225847..19225973,19226040..19226139); ID=FBpp0085692; name=hppy-PA; parent=FBgn0263395,FBtr0086504; dbxref=FlyBase:FBpp0085692,FlyBase_Annotation_IDs:CG7097-PA,GB_protein:AAF57595.1,REFSEQ:NP_725863,GB_protein:AAF57595,FlyMine:FBpp0085692,modMine:FBpp0085692; MD5=8fee56e25c8d9b56f77672788da67029; length=1218; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(19179733..19179858,19211856..19212276,19216421..19216519,19216743..19217041,19217757..19217844,19218131..19218194,19220744..19220782,19223240..19224386,19224450..19224576,19224641..19224994,19225060..19225503,19225565..19225786,19225847..19225973,19226040..19226139); ID=FBpp0085692; name=hppy-PA; parent=FBgn0263395,FBtr0086504; dbxref=FlyBase:FBpp0085692,FlyBase_Annotation_IDs:CG7097-PA,GB_protein:AAF57595.1,REFSEQ:NP_725863,GB_protein:AAF57595,FlyMine:FBpp0085692,modMine:FBpp0085692; MD5=8fee56e25c8d9b56f77672788da67029; length=1218; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0085692 type=protein; loc=2R:join(19179733..19179858,19211856..19212276,19216421..19216519,19216743..19217041,19217757..19217844,19218131..19218194,19220744..19220782,19223240..19224386,19224450..19224576,19224641..19224994,19225060..19225503,19225565..19225786,19225847..19225973,19226040..19226139); ID=FBpp0085692; name=hppy-PA; parent=FBgn0263395,FBtr0086504; dbxref=FlyBase:FBpp0085692,FlyBase_Annotation_IDs:CG7097-PA,GB_protein:AAF57595.1,REFSEQ:NP_725863,GB_protein:AAF57595,FlyMine:FBpp0085692,modMine:FBpp0085692; MD5=8fee56e25c8d9b56f77672788da67029; length=1218; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(19179733..19179858,19211856..19212276,19216421..19216519,19216743..19217041,19217757..19217844,19218131..19218194,19220744..19220782,19223240..19224386,19224450..19224576,19224641..19224994,19225060..19225503,19225565..19225786,19225847..19225973,19226040..19226139); ID=FBpp0085692; name=hppy-PA; parent=FBgn0263395,FBtr0086504; dbxref=FlyBase:FBpp0085692,FlyBase_Annotation_IDs:CG7097-PA,GB_protein:AAF57595.1,REFSEQ:NP_725863,GB_protein:AAF57595,UniProt/TrEMBL:A1ZBH7,FlyMine:FBpp0085692,modMine:FBpp0085692; MD5=8fee56e25c8d9b56f77672788da67029; length=1218; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1218 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: behavioral response to ethanol [IMP]
    protein amino acid phosphorylation [IGI][NAS]
    negative regulation of epidermal growth factor receptor signaling pathway [IGI]
    positive regulation of TOR signaling pathway [IGI]
    Molecular Function: ATP binding [IEA]
    receptor signaling protein serine/threonine kinase activity [NAS]
    small GTPase regulator activity [IEA]
    protein kinase activity [IGI]
    protein serine/threonine kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAHSHHNA NMLSSDISRR NPQDEYELIQ KIGSGTYGDV YKAKRIQSNE LAAIKVIKLE  60
   61 PSDDIQIIQQ EIIMMRDCRH PNIIAYYGSY LRRDKLWICM EFCGGGSLQD IYQVTGPLTE 120
  121 VQIAYMCRET LKGLEYLHSM GKMHRDIKGA NILLTEYGDV KLADFGVSAQ ITATINKRKS 180
  181 FIGTPYWMAP EVAAVERKGG YNQLCDIWAC GITAIELAEL QPPMFDLHPM RALFLMSKSG 240
  241 FKPPTLNNKD KWSPTFHNFI KTALTKNPKK RPTAERLLQH PFVQCEMSLR VAKELLQKYQ 300
  301 SPNPQFYYYL DGDEESVAGV PQRIASKMTS RTNGVPAQNH TLKTGMTTNS TWNERSSSPE 360
  361 TLPSDMSLLQ YIDEELKLRA TLPLNNDTKD PLGAECSCSS HNGGAAGGGG GGGVGVGAGG 420
  421 AAANGSSSSS GGATVGTTHH QHQQHHQHHH HPNHLHQHQS HQLPQQQQQQ SHQAAQQEHH 480
  481 HHHPMTSSIS SGLVTANANN ISSSASLASM PGLSAYLGMR SHVVGHMGMG FGMGLGMSNL 540
  541 RTTSIDADDD ELVAADVAMN NAAAAVPGNG SGAGNGSGSG CSASAAHYLR YSSNYRSAAA 600
  601 AQASQAAHPH VNSNSNSNNG HGHAPITSSI SSSASSASFY NRLLLLDNSS GDAVVGGNGG 660
  661 GSSNISSSGG ASSGTNGLLD KHELDALPQA ATKSAGDGFS HSNSPTANSG AGATGSRDND 720
  721 GPSSSNSSHL YQNLLRSSSG ETPAGSSSAG NNCDYRHENN QNGLEDSPRR HSSMDQLIGL 780
  781 LENMGKSPRT RSLSDGGTQD DDEAEKEAQP DLLNNTPPVP PKRSHKRRHT PPRPISNGLP 840
  841 PTPKVHMGAC FSKIFNGCPL RVHCTASWIH PETRDQHLLI GAEEGIYNLN MNELHDAAID 900
  901 QLFPRRTTWL YVIKDVLMSL SGKSCQLYRH DLVALHSKQT VRFSLHMNKI PERLVPRKFA 960
  961 LTTKVPDTKC CTQCCVTRNP YNGYKYLCGA TPSGIFLMQW YDPLNKFMLL KQCEWPAISI1020
 1021 QGGGHGCVQN GHTPVFEMII TPELEYPIVC TGVRKAMNGC LKLELINMNS ASWFHSEDLE1080
 1081 YDAMATMVPR RDLLKVVRVH QVEKDAILVC YGNLIQVVTL QGNPKQHKKM VSQLNFDFNV1140
 1141 DSIVCLPDSV LAFHKHGMQG KSLRNGEVTQ EIKDMSRTYR LLGSDKVVAL ESQLLRTGSL1200
 1201 GSEEGHDLYI LAGHEASY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..302] PSI-BLAST 62.522879 No description for 2j51A was found.
    2 View Details [303..403] deduced N/A No confident structure predictions are available.
    3 View Details [404..607] deduced N/A No confident structure predictions are available.
    4 View Details [608..730] deduced N/A No confident structure predictions are available.
    5 View Details [731..857] deduced N/A No confident structure predictions are available.
    6 View Details [858..1084] deduced N/A No confident structure predictions are available.
    7 View Details [1085..1218] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • acetylcholine receptor activator activity
    		•  5.9159846946654 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.49988294224815 bayes_pls_golite062009
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • kinase activity
    		•  5.3287080791198 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.96052051118534 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • transferase activity
    		•  3.97138602499442 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  3.41480681854114 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  3.40140621607334 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  2.8153155526437 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  2.59526003830791 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • signal transducer activity
    		•  2.40586892801446 bayes_pls_golite062009
  • receptor activity
    		•  2.39311927684508 bayes_pls_golite062009
  • protein binding
    		•  2.276111749106 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.12615078788254 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  2.10379226653669 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.94085498993561 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • actin binding
    		•  1.87817875565699 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.81249386965144 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.74206248731815 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • growth factor binding
    		•  1.53863828216563 bayes_pls_golite062009
  • ErbB-3 class receptor binding
    		•  1.34841233233438 bayes_pls_golite062009
  • ErbB-2 class receptor binding
    		•  1.33825339298024 bayes_pls_golite062009
  • kinase binding
    		•  1.26086833316556 bayes_pls_golite062009
  • phosphoinositide 3-kinase binding
    		•  1.25285260301349 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  1.2266791546014 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • transporter activity
    		•  1.11833481501707 bayes_pls_golite062009
  • non-membrane spanning protein tyrosine kinase activity
    		•  1.11664317075762 bayes_pls_golite062009
  • transforming growth factor beta receptor activity
    		•  1.10045286406485 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase activity
    		•  1.10045286406485 bayes_pls_golite062009
  • protein kinase binding
    		•  1.06030596516506 bayes_pls_golite062009
  • insulin receptor substrate binding
    		•  0.98689034826741 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.97575992765505 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.959360414036299 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.81943579965027 bayes_pls_golite062009
  • actin filament binding
    		•  0.794152600084 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.794058505655489 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.775404673285876 bayes_pls_golite062009
  • fibroblast growth factor receptor activity
    		•  0.75189004129952 bayes_pls_golite062009
  • DNA binding
    		•  0.714163549867672 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.705905455086486 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.612883428421652 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.568332175782799 bayes_pls_golite062009
  • transcription factor activity
    		•  0.563262875317016 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.51726292539973 bayes_pls_golite062009
  • activin binding
    		•  0.510364757301021 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
    		•  0.48345772948903 bayes_pls_golite062009
  • enzyme binding
    		•  0.46284745266176 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.450699332958421 bayes_pls_golite062009
  • structural constituent of muscle
    		•  0.399773397398032 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • tubulin binding
    		•  0.385009627613955 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
    		•  0.37115026509016 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  0.35402045013148 bayes_pls_golite062009
  • protein complex binding
    		•  0.239339759110451 bayes_pls_golite062009
  • insulin receptor activity
    		•  0.188254408239569 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.148194101970458 bayes_pls_golite062009
  • transforming growth factor beta receptor activity, type I
    		•  0.0506751594607393 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0040394359628233 bayes_pls_golite062009
  • brain-derived neurotrophic factor binding
    		•  0.00315481858218991 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle