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Protein Overview: STA5B_RAT

General Information:
Name(s) found: STA5B_RAT [Swiss-Prot]
Description(s) found:
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  • gi|1711557|sp|P52632.1|STA5B_RAT RecName: Full=Signal transducer and activator of transcription 5B [NCBI NR]
  • gi|1143542|emb|CAA63042.1| stat5b [Rattus norvegicus] [NCBI NR]
  • Signal transducer and activator of transcription 5B OS=Rattus norvegicus GN=Stat5b PE=1 SV=1 [Swiss-Prot]
  • (P52632) Signal transducer and activator of transcription 5B [Swiss-Prot]
  • Ensembl_locations(Chr-bp):10-87958956 Signal transducer and activator of transcription 5B [hmr_yeast5_DM3-1_pombe.fasta]
  • stat5b [Rattus norvegicus]gi|1711557|sp|P52632|ST5B_RAT Signal transducer and activator of transcription 5B [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Signal transducer and activator of transcription 5B [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • Signal transducer and activator of transcription 5B [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • stat5b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 5B [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Stat5b Signal transducer and activator of transcription 5B [rat-ipi-250309-contam.fasta]
  • Signal transducer and activator of transcription 5B OS=Rattus norvegicus GN=Stat5b [011711_HMR.fasta]
  • Signal transducer and activator of transcription 5B OS=Rattus norvegicus GN=Stat5b PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
    • Organism: Rattus norvegicus
    Length: 786 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IDA]
    cytoplasm [UNKNOWN][IEA]
    cytosol [IDA]
    Biological Process: lipid storage [UNKNOWN][IEA]
    positive regulation of survival gene product expression [UNKNOWN][IEA]
    transcription from RNA polymerase II promoter [IDA]
    creatine metabolic process [IEA]
    negative regulation of erythrocyte differentiation [UNKNOWN][IEA]
    allantoin metabolic process [IEA]
    JAK-STAT cascade [UNKNOWN][IDA]
    T cell homeostasis [UNKNOWN][IEA]
    response to hypoxia [IEP]
    JAK-STAT cascade involved in growth hormone signaling pathway [UNKNOWN][IEA]
    positive regulation of inflammatory response [UNKNOWN][IEA]
    development of secondary female sexual characteristics [UNKNOWN][IEA]
    valine metabolic process [IEA]
    development of secondary male sexual characteristics [UNKNOWN][IEA]
    positive regulation of activated T cell proliferation [UNKNOWN][IEA]
    response to peptide hormone stimulus [IDA][IEP]
    positive regulation of B cell differentiation [UNKNOWN][IEA]
    positive regulation of mitotic cell cycle [UNKNOWN][IEA]
    luteinization [UNKNOWN][IDA]
    regulation of epithelial cell differentiation [UNKNOWN][IEA]
    response to interleukin-15 [UNKNOWN][IEA]
    response to interleukin-4 [UNKNOWN][IEA]
    response to estradiol stimulus [UNKNOWN][IEA]
    cellular response to hormone stimulus [UNKNOWN][IEA]
    positive regulation of cell proliferation [UNKNOWN]
    citrate metabolic process [IEA]
    positive regulation of gamma-delta T cell differentiation [UNKNOWN][IEA]
    positive regulation of lymphocyte differentiation [UNKNOWN]
    positive regulation of cellular component movement [IMP]
    lactation [UNKNOWN][IEA]
    succinate metabolic process [IEA]
    positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA]
    2-oxoglutarate metabolic process [IEA]
    positive regulation of multicellular organism growth [UNKNOWN][IEA]
    positive regulation of natural killer cell differentiation [UNKNOWN][IEA]
    positive regulation of smooth muscle cell proliferation [IMP]
    response to ethanol [IEP]
    sex differentiation [UNKNOWN][IEA]
    liver development [IDA]
    cytokine-mediated signaling pathway [UNKNOWN][IEA]
    Peyer's patch development [UNKNOWN][IEA]
    response to interleukin-2 [UNKNOWN][IEA]
    progesterone metabolic process [UNKNOWN][IEA]
    signal transduction [IEA]
    T cell differentiation in the thymus [UNKNOWN][IEA]
    regulation of transcription, DNA-dependent [IDA]
    female pregnancy [UNKNOWN][IEA]
    acute-phase response [IDA]
    fatty acid metabolic process [IEA]
    regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    positive regulation of natural killer cell mediated cytotoxicity [UNKNOWN][IEA]
    creatinine metabolic process [IEA]
    isoleucine metabolic process [IEA]
    positive regulation of interleukin-2 biosynthetic process [UNKNOWN][IEA]
    oxaloacetate metabolic process [IEA]
    positive regulation of natural killer cell proliferation [UNKNOWN][IEA]
    natural killer cell differentiation [UNKNOWN]
    negative regulation of apoptosis [UNKNOWN][IEA]
    taurine metabolic process [IEA]
    response to lipopolysaccharide [IDA]
    regulation of cell adhesion [UNKNOWN][IEA]
    regulation of steroid metabolic process [UNKNOWN][IEA]
    Molecular Function: DNA binding [UNKNOWN][IDA]
    transcription factor activity [IDA]
    protein binding [UNKNOWN][IEA]
    calcium ion binding [IEA]
    double-stranded DNA binding [IDA]
    sequence-specific DNA binding [IDA]
    signal transducer activity [UNKNOWN][IEA]
    glucocorticoid receptor binding [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMWIQAQQL QGDALHQMQA LYGQHFPIEV RHYLSQWIES QAWDSIDLDN PQENIKATQL  60
   61 LEGLVQELQK KAEHQVGEDG FLLKIKLGHY ATQLQNTYDR CPMELVRCIR HILYNEQRLV 120
  121 REANNGSSPA GSLADAMSQK HLQINQTFEE LRLITQDTES ELKKLQQTQE YFIIQYQESL 180
  181 RIQAQFAQLA QLNPQERMSR ETALQQKQVS LETWLQREAQ TLQQYRVELA EKHQKTLQLL 240
  241 RKQQTIILDD ELIQWKRRQQ LAGNGGPPEG SLDVLQSWCE KLAEIIWQNR QQIRRLEHLC 300
  301 QQLPIPGPVE EMLAEVNATI TDIISALSTS TFIIEKQPPQ VLKTQTKFAA TVRLLVGGKL 360
  361 NVHMNPPQVK ATIISEQQAK SLLKNENTRN DYSGEILNNC CVMEYHQATG TLSAHFRNMS 420
  421 LKRIKRSDRR GAESVTEEKF TILFDSQFSV GGNELVFQVK TLSLPVVVIV HGSQDNNATA 480
  481 TVLWDNAFRE PGRVPFAVPD KVLWPQLCEA LNMKFKAEVQ SNRGLTKENL VFLAQKLFNS 540
  541 SSNHLEDYNS MSVSWSQFNR ENLPGRNYTF WQWFDGVMEV LKKHLKPHWN DGAILGFVNK 600
  601 QQAHDLLINK PDGTFLLRFS DSEIGGITIA WKFDSQERMF WNLMPFTTRD FSIRSLADRL 660
  661 GDLNYLIYVF PDRPKDEVYS KYYTPVPCER ATAKAADGYV KPQIKQVVPE FVNASTDAGS 720
  721 GATYMDQAPS PVVCPQAHYN MYPQNPDSVL DTDGDFDLED TMDVARRVEE LLGRPMDSQW 780
  781 IPHAQS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle