YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth. The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand. The process by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes. Any process by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of cytokines to their cognate receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes. The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand. A series of reactions that occur within the cell, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: JAK-STAT cascade involved in growth hormone signaling pathway
Acc: GO:0060397
Aspect: Biological Process
Desc: The process by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
Synonyms:
  • JAK-STAT cascade involved in growth hormone signalling pathway
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060397 - JAK-STAT cascade involved in growth hormone signaling pathway (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle