YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: TGFB3_RAT

General Information:
Name(s) found: TGFB3_RAT [Swiss-Prot]
Description(s) found:
Found 20 descriptions.
SHOW ALL
  • Transforming growth factor beta-3 OS=Rattus norvegicus GN=Tgfb3 PE=2 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 412 amino acids

    Gene Ontology:
    Cellular Component: platelet alpha granule lumen [UNKNOWN]
    nucleus [IDA]
    T-tubule [IDA]
    extracellular space [IDA]
    cytoplasm [IDA]
    secretory granule [IDA]
    extracellular matrix [UNKNOWN][IEA]
    neuronal cell body [IDA]
    extracellular region [UNKNOWN][IEA]
    cell surface [IDA]
    Biological Process: embryonic development [UNKNOWN][IEA]
    frontal suture morphogenesis [IEP]
    response to estrogen stimulus [IDA]
    inner ear development [IEP]
    negative regulation of cell proliferation [UNKNOWN][IDA]
    response to progesterone stimulus [UNKNOWN][IEA]
    transforming growth factor beta receptor signaling pathway [UNKNOWN]
    positive regulation of filopodium assembly [UNKNOWN][IEA]
    menstrual cycle phase [UNKNOWN][IEA]
    positive regulation of DNA replication [UNKNOWN][IEA]
    positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA]
    regulation of endothelial cell differentiation [TAS]
    salivary gland morphogenesis [UNKNOWN][IEA]
    negative regulation of neuron apoptosis [UNKNOWN][IEA]
    positive regulation of epithelial to mesenchymal transition [UNKNOWN][IEA]
    activation of MAPK activity [IDA]
    wound healing [IEP]
    response to hypoxia [UNKNOWN][IEP]
    positive regulation of collagen biosynthetic process [UNKNOWN][IEA]
    positive regulation of gene-specific transcription [UNKNOWN]
    positive regulation of cell division [IEA]
    in utero embryonic development [UNKNOWN][IEA]
    induction of apoptosis [UNKNOWN][IEA]
    gut development [IEP]
    detection of hypoxia [UNKNOWN][IEA]
    positive regulation of protein secretion [UNKNOWN][IEA]
    regulation of epithelial cell proliferation [TAS]
    positive regulation of bone mineralization [UNKNOWN][IEA]
    lung development [NAS]
    SMAD protein nuclear translocation [IDA]
    embryonic neurocranium morphogenesis [IDA]
    female pregnancy [IEP]
    negative regulation of DNA replication [UNKNOWN][IEA]
    aging [IEP]
    ossification involved in bone remodeling [UNKNOWN][IEA]
    cell-cell junction organization [UNKNOWN][IEA]
    organ morphogenesis [UNKNOWN][IEA]
    mammary gland development [UNKNOWN][IEA]
    regulation of epithelial cell differentiation [TAS]
    response to laminar fluid shear stress [IEP]
    cellular response to growth factor stimulus [UNKNOWN]
    positive regulation of apoptosis [IDA][IMP]
    cell growth [IEA]
    negative regulation of transforming growth factor beta receptor signaling pathway [IDA]
    Molecular Function: transforming growth factor beta binding [UNKNOWN][IEA]
    growth factor activity [IEA]
    identical protein binding [UNKNOWN][IEA]
    protein binding [UNKNOWN]
    transforming growth factor beta receptor binding [TAS]
    protein heterodimerization activity [IDA]
    type II transforming growth factor beta receptor binding [UNKNOWN][IEA]
    type I transforming growth factor beta receptor binding [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKMHLQRALV VLALLNLATV SLSLSTCTTL DFGHIKKKRV EAIRGQILSK LRLTSPPEPS  60
   61 VMTHVPYQVL ALYNSTRELL EEMHGEREEG CTQETSESEY YAKEIHKFDM IQGLAEHNEL 120
  121 AVCPKGITSK VFRFNVSSVE KNGTNLFRAE FRVLRVPNPS SKRTEQRIEL FQILRPDEHI 180
  181 AKQRYIGGKN LPTRGTAEWL SFDVTDTVRE WLLRRESNLG LEISIHCPCH TFQPNGDILE 240
  241 NVHEVMEIKF KGVDNEDDHG RGDLGRLKKQ KDHHNPHLIL MMIPPHRLDS PGQGGQRKKR 300
  301 ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSSDTTHST 360
  361 VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle