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Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell. A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG). A membrane-bounded vesicle found in the cytoplasm of the cell. The volume enclosed by the membrane or protein that forms a vesicle. The volume enclosed by the membrane of the platelet alpha granule. The volume enclosed by the membrane of a cytoplasmic membrane-bounded vesicle. A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: platelet alpha granule lumen
Acc: GO:0031093
Aspect: Cellular Component
Desc: The volume enclosed by the membrane of the platelet alpha granule.
Synonyms:
  • platelet alpha-granule lumen
Proteins in PDR annotated with:
   This term: 71 [Search]
   Term or descendants: 71 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031093 - platelet alpha granule lumen (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle