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Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway. Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. Any process that stops, prevents or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands. Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway. Any process that stops, prevents or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of transforming growth factor beta receptor signaling pathway
Acc: GO:0030512
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
Synonyms:
  • down-regulation of transforming growth factor beta receptor signaling pathway
  • downregulation of transforming growth factor beta receptor signaling pathway
  • negative regulation of TGFbeta receptor signaling pathway
  • negative regulation of transforming growth factor beta receptor signalling pathway
  • inhibition of transforming growth factor beta receptor signaling pathway
  • down regulation of transforming growth factor beta receptor signaling pathway
  • negative regulation of TGF-beta receptor signaling pathway
Proteins in PDR annotated with:
   This term: 80 [Search]
   Term or descendants: 80 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle