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A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components. The formation of bone involved in the continuous turnover of bone matrix and mineral. The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling. The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis. The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: ossification involved in bone remodeling
Acc: GO:0043932
Aspect: Biological Process
Desc: The formation of bone involved in the continuous turnover of bone matrix and mineral.
Synonyms:
  • ossification involved in bone remodelling
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043932 - ossification involved in bone remodeling (interactive image map)
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